PL429929A1 - Sposób wytwarzania 1-(N-imido)alkilofosfonianów, 1-(N-imido)alkilofosfinianów i tlenków 1-(N-imido)alkilofosfin - Google Patents
Sposób wytwarzania 1-(N-imido)alkilofosfonianów, 1-(N-imido)alkilofosfinianów i tlenków 1-(N-imido)alkilofosfinInfo
- Publication number
- PL429929A1 PL429929A1 PL429929A PL42992919A PL429929A1 PL 429929 A1 PL429929 A1 PL 429929A1 PL 429929 A PL429929 A PL 429929A PL 42992919 A PL42992919 A PL 42992919A PL 429929 A1 PL429929 A1 PL 429929A1
- Authority
- PL
- Poland
- Prior art keywords
- imido
- alkylphosphonates
- alkylphosphinates
- producing
- ome
- Prior art date
Links
- 125000005600 alkyl phosphonate group Chemical group 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 abstract 6
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 abstract 6
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 abstract 6
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 abstract 4
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 2
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 abstract 2
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 abstract 2
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 abstract 1
- 238000004440 column chromatography Methods 0.000 abstract 1
- 239000012043 crude product Substances 0.000 abstract 1
- 238000002425 crystallisation Methods 0.000 abstract 1
- 230000008025 crystallization Effects 0.000 abstract 1
- 239000003480 eluent Substances 0.000 abstract 1
- 239000012038 nucleophile Substances 0.000 abstract 1
- 229910052698 phosphorus Inorganic materials 0.000 abstract 1
- 239000011574 phosphorus Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- IZYFBZDLXRHRLF-UHFFFAOYSA-N tritylphosphane;hydroiodide Chemical compound [I-].C=1C=CC=CC=1C(C=1C=CC=CC=1)([PH3+])C1=CC=CC=C1 IZYFBZDLXRHRLF-UHFFFAOYSA-N 0.000 abstract 1
Abstract
Przedmiotem zgłoszenia jest sposób wytwarzania 1-(N-imido)alkilofosfonianów, 1-(N-imido)alkilofosfinianów i tlenków 1-(N-imido)alkilofosfin o wzorze ogólnym 1, w którym A (CH2)2, o-C6H4; R1 = H, Me,i-Bu, Ph; R2 = R3 = OMe, OEt, Ph, lub R2 = OMe, R3 = Ph, który polega na tym, że sole 1-(N-imido)alkilofosfoniowe o wzorze ogólnym 2, w którym A = (CH2)2, o-C6H4; R1 = H, Me, i-Bu, Ph; R = Ph, m-C6H4Cl, p-C6H4CF3 ogrzewa się w temperaturze 80°-170°C z nukleofilami fosforowymi w stosunku molowym od 1:1,5 do 1:10, korzystnie 1:10, w CHCl3, CH2Cl2 lub CH3CN, korzystnie z dodatkiem jodku trifenylometylofosfoniowego, w czasie 30-120 min, po czym surowy produkt oczyszcza się metodą chromatografii kolumnowej za pomocą eluenta w postaci octanu etylu, acetonitrylu lub układu octan etyl/heksan, następnie oczyszcza poprzez krystalizację z toluenu lub układu toluen/heksan.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL429929A PL239833B1 (pl) | 2019-05-15 | 2019-05-15 | Sposób wytwarzania 1-(N-imido)alkilofosfonianów, 1-(N-imido) alkilofosfinianów i tlenków 1-(N-imido)alkilofosfin |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL429929A PL239833B1 (pl) | 2019-05-15 | 2019-05-15 | Sposób wytwarzania 1-(N-imido)alkilofosfonianów, 1-(N-imido) alkilofosfinianów i tlenków 1-(N-imido)alkilofosfin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL429929A1 true PL429929A1 (pl) | 2020-11-16 |
| PL239833B1 PL239833B1 (pl) | 2022-01-17 |
Family
ID=73196987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL429929A PL239833B1 (pl) | 2019-05-15 | 2019-05-15 | Sposób wytwarzania 1-(N-imido)alkilofosfonianów, 1-(N-imido) alkilofosfinianów i tlenków 1-(N-imido)alkilofosfin |
Country Status (1)
| Country | Link |
|---|---|
| PL (1) | PL239833B1 (pl) |
-
2019
- 2019-05-15 PL PL429929A patent/PL239833B1/pl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL239833B1 (pl) | 2022-01-17 |
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