PL428750A1 - 2'-O-β-D-(4"-O-Methylglucopyranosyl)-5'-methoxyflavone and method of preparing 2'-O-β-D-(4"-O-methylglucopyranosyl)-5'-methoxyflavone - Google Patents

2'-O-β-D-(4"-O-Methylglucopyranosyl)-5'-methoxyflavone and method of preparing 2'-O-β-D-(4"-O-methylglucopyranosyl)-5'-methoxyflavone

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Publication number
PL428750A1
PL428750A1 PL428750A PL42875019A PL428750A1 PL 428750 A1 PL428750 A1 PL 428750A1 PL 428750 A PL428750 A PL 428750A PL 42875019 A PL42875019 A PL 42875019A PL 428750 A1 PL428750 A1 PL 428750A1
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PL
Poland
Prior art keywords
methylglucopyranosyl
methoxyflavone
preparing
methylglycosylation
kch
Prior art date
Application number
PL428750A
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Polish (pl)
Other versions
PL243365B1 (en
Inventor
Mateusz Łużny
Ewa Kozłowska
Tomasz Tronina
Edyta Kostrzewa-Susłow
Tomasz Janeczko
Original Assignee
Uniwersytet Przyrodniczy we Wrocławiu
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Publication date
Application filed by Uniwersytet Przyrodniczy we Wrocławiu filed Critical Uniwersytet Przyrodniczy we Wrocławiu
Priority to PL428750A priority Critical patent/PL243365B1/en
Publication of PL428750A1 publication Critical patent/PL428750A1/en
Publication of PL243365B1 publication Critical patent/PL243365B1/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Wynalazek dotyczy 2'-O-ß-D-(4"-O-metyloglukopiranozylo)-5'-metoksyflawonu i sposobu wytwarzania 2'-O-ß-D-(4"-O-metyloglukopiranozylo)-5'-metoksyflawonu o wzorze 2. W wyniku działania układu enzymatycznego zawartego w komórkach szczepu Isaria farinosa KCh KW1.1, następuje O-demetylacja i 4"-O-metyloglikozylacja. Uzyskany w ten sposób produkt wydziela się z wodnej kultury mikroorganizmu, znanym sposobem, przez ekstrakcję rozpuszczalnikiem organicznym niemieszającym się z wodą (octan etylu).The invention relates to 2'-O-ß-D- (4 "-O-methylglucopyranosyl) -5'-methoxyflavone and a process for the preparation of 2'-O-ß-D- (4" -O-methylglucopyranosyl) -5'-methoxyflavone As a result of the enzyme system contained in the cells of the strain Isaria farinosa KCh KW1.1, O-demethylation and 4 "-O-methylglycosylation take place. The product obtained in this way is separated from the water culture of the microorganism by a known method, by extraction with an organic solvent water-immiscible (ethyl acetate).

PL428750A 2019-01-31 2019-01-31 2'-O-β-D-(4"-O-Methylglucopyranosyl)-5'-methoxyflavone and method of preparing 2'-O-β-D-(4"-O-methylglucopyranosyl)-5'-methoxyflavone PL243365B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL428750A PL243365B1 (en) 2019-01-31 2019-01-31 2'-O-β-D-(4"-O-Methylglucopyranosyl)-5'-methoxyflavone and method of preparing 2'-O-β-D-(4"-O-methylglucopyranosyl)-5'-methoxyflavone

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL428750A PL243365B1 (en) 2019-01-31 2019-01-31 2'-O-β-D-(4"-O-Methylglucopyranosyl)-5'-methoxyflavone and method of preparing 2'-O-β-D-(4"-O-methylglucopyranosyl)-5'-methoxyflavone

Publications (2)

Publication Number Publication Date
PL428750A1 true PL428750A1 (en) 2020-08-10
PL243365B1 PL243365B1 (en) 2023-08-14

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Family Applications (1)

Application Number Title Priority Date Filing Date
PL428750A PL243365B1 (en) 2019-01-31 2019-01-31 2'-O-β-D-(4"-O-Methylglucopyranosyl)-5'-methoxyflavone and method of preparing 2'-O-β-D-(4"-O-methylglucopyranosyl)-5'-methoxyflavone

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PL (1) PL243365B1 (en)

Also Published As

Publication number Publication date
PL243365B1 (en) 2023-08-14

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