PL428748A1 - 5'-O-β-D-(4"-O-Methylglucopyranosyl)-2'-methoxyflavone and method of preparing 5'-O-β-D-(4"-O-methylglucopyranosyl)-2'-methoxyflavon - Google Patents

5'-O-β-D-(4"-O-Methylglucopyranosyl)-2'-methoxyflavone and method of preparing 5'-O-β-D-(4"-O-methylglucopyranosyl)-2'-methoxyflavon

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Publication number
PL428748A1
PL428748A1 PL428748A PL42874819A PL428748A1 PL 428748 A1 PL428748 A1 PL 428748A1 PL 428748 A PL428748 A PL 428748A PL 42874819 A PL42874819 A PL 42874819A PL 428748 A1 PL428748 A1 PL 428748A1
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PL
Poland
Prior art keywords
methylglucopyranosyl
methoxyflavone
methoxyflavon
preparing
methylglycosylation
Prior art date
Application number
PL428748A
Other languages
Polish (pl)
Other versions
PL241001B1 (en
Inventor
Mateusz Łużny
Ewa Kozłowska
Tomasz Tronina
Edyta Kostrzewa-Susłow
Tomasz Janeczko
Original Assignee
Uniwersytet Przyrodniczy we Wrocławiu
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Publication date
Application filed by Uniwersytet Przyrodniczy we Wrocławiu filed Critical Uniwersytet Przyrodniczy we Wrocławiu
Priority to PL428748A priority Critical patent/PL241001B1/en
Publication of PL428748A1 publication Critical patent/PL428748A1/en
Publication of PL241001B1 publication Critical patent/PL241001B1/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Wynalazek dotyczy 5'-O-ß-D-(4"-O-metyloglukopiranozylo)-2'-metoksyflawonu i sposobu wytwarzania 5'-O-ß-D-(4"-O-metyloglukopiranozylo)-2'-metoksyflawonu o wzorze 2. W wyniku działania układu enzymatycznego zawartego w komórkach szczepu Isaria farinosa KCh KW1.1, następuje O-demetylacja i 4"-O-metyloglikozylacja. Uzyskany w ten sposób produkt wydziela się z wodnej kultury mikroorganizmu, znanym sposobem, przez ekstrakcję rozpuszczalnikiem organicznym niemieszającym się z wodą (octan etylu).The invention relates to 5'-O-ß-D- (4 "-O-methylglucopyranosyl) -2'-methoxyflavone and a process for the preparation of 5'-O-ß-D- (4" -O-methylglucopyranosyl) -2'-methoxyflavone with As a result of the enzyme system contained in the cells of the strain Isaria farinosa KCh KW1.1, O-demethylation and 4 "-O-methylglycosylation take place. The product obtained in this way is separated from the water culture of the microorganism by a known method, by extraction with an organic solvent water-immiscible (ethyl acetate).

PL428748A 2019-01-31 2019-01-31 5'-O-β-D-(4"-O-Methylglucopyranosyl)-2'-methoxyflavone and method of preparing 5'-O-β-D-(4"-O-methylglucopyranosyl)-2'-methoxyflavon PL241001B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL428748A PL241001B1 (en) 2019-01-31 2019-01-31 5'-O-β-D-(4"-O-Methylglucopyranosyl)-2'-methoxyflavone and method of preparing 5'-O-β-D-(4"-O-methylglucopyranosyl)-2'-methoxyflavon

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL428748A PL241001B1 (en) 2019-01-31 2019-01-31 5'-O-β-D-(4"-O-Methylglucopyranosyl)-2'-methoxyflavone and method of preparing 5'-O-β-D-(4"-O-methylglucopyranosyl)-2'-methoxyflavon

Publications (2)

Publication Number Publication Date
PL428748A1 true PL428748A1 (en) 2020-08-10
PL241001B1 PL241001B1 (en) 2022-07-11

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Family Applications (1)

Application Number Title Priority Date Filing Date
PL428748A PL241001B1 (en) 2019-01-31 2019-01-31 5'-O-β-D-(4"-O-Methylglucopyranosyl)-2'-methoxyflavone and method of preparing 5'-O-β-D-(4"-O-methylglucopyranosyl)-2'-methoxyflavon

Country Status (1)

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PL (1) PL241001B1 (en)

Also Published As

Publication number Publication date
PL241001B1 (en) 2022-07-11

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