PL427993A1 - New sulfonamide derivatives of 5-phenyl-7-methyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine, method of their preparation, their uses and a pharmaceutical composition containing them - Google Patents

New sulfonamide derivatives of 5-phenyl-7-methyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine, method of their preparation, their uses and a pharmaceutical composition containing them

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Publication number
PL427993A1
PL427993A1 PL427993A PL42799318A PL427993A1 PL 427993 A1 PL427993 A1 PL 427993A1 PL 427993 A PL427993 A PL 427993A PL 42799318 A PL42799318 A PL 42799318A PL 427993 A1 PL427993 A1 PL 427993A1
Authority
PL
Poland
Prior art keywords
tetrazolo
pyrazolo
triazine
phenyl
methyl
Prior art date
Application number
PL427993A
Other languages
Polish (pl)
Other versions
PL237894B1 (en
Inventor
Anna Bielawska
Krzysztof Bielawski
Wojciech Szymanowski
Mariusz Mojzych
Katarzyna Kotwica-Mojzych
Original Assignee
Uniwersytet Medyczny W Białymstoku
Uniwersytet Przyrodniczo-Humanistyczny W Siedlcach
Uniwersytet Medyczny W Lublinie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Uniwersytet Medyczny W Białymstoku, Uniwersytet Przyrodniczo-Humanistyczny W Siedlcach, Uniwersytet Medyczny W Lublinie filed Critical Uniwersytet Medyczny W Białymstoku
Priority to PL427993A priority Critical patent/PL237894B1/en
Publication of PL427993A1 publication Critical patent/PL427993A1/en
Publication of PL237894B1 publication Critical patent/PL237894B1/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Przedmiotem zgłoszenia są achiralne pochodne sulfonamidowe 5-fenylo-7-metylo-pirazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazyny. Związki te wykazują aktywność przeciwnowotworową, cytostatyczną, cytotoksyczną i antyproliferacyjną. Przedmiotem zgłoszenia jest także sposób wytwarzania pochodnych sulfonamidowych 5-fenylo-7-metylo-pirazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazyny oraz zastosowania takich związków i kompozycja farmaceutyczna je zawierająca.The subject of the application are 5-phenyl-7-methyl-pyrazolo [4,3-e] tetrazolo [4,5-b] [1,2,4] triazine achiral sulfonamide derivatives. These compounds exhibit antitumor, cytostatic, cytotoxic and antiproliferative activity. The subject of the application is also a process for the preparation of 5-phenyl-7-methyl-pyrazolo [4,3-e] tetrazolo [4,5-b] [1,2,4] triazine sulfonamide derivatives and the use of such compounds and a pharmaceutical composition containing them.

PL427993A 2018-11-30 2018-11-30 New sulfonamide derivatives of 5-phenyl-7-methyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine, method of their preparation, their uses and a pharmaceutical composition containing them PL237894B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL427993A PL237894B1 (en) 2018-11-30 2018-11-30 New sulfonamide derivatives of 5-phenyl-7-methyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine, method of their preparation, their uses and a pharmaceutical composition containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL427993A PL237894B1 (en) 2018-11-30 2018-11-30 New sulfonamide derivatives of 5-phenyl-7-methyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine, method of their preparation, their uses and a pharmaceutical composition containing them

Publications (2)

Publication Number Publication Date
PL427993A1 true PL427993A1 (en) 2020-06-01
PL237894B1 PL237894B1 (en) 2021-06-14

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Family Applications (1)

Application Number Title Priority Date Filing Date
PL427993A PL237894B1 (en) 2018-11-30 2018-11-30 New sulfonamide derivatives of 5-phenyl-7-methyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine, method of their preparation, their uses and a pharmaceutical composition containing them

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PL (1) PL237894B1 (en)

Also Published As

Publication number Publication date
PL237894B1 (en) 2021-06-14

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