PL427993A1 - New sulfonamide derivatives of 5-phenyl-7-methyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine, method of their preparation, their uses and a pharmaceutical composition containing them
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New sulfonamide derivatives of 5-phenyl-7-methyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine, method of their preparation, their uses and a pharmaceutical composition containing them
Uniwersytet Przyrodniczo-Humanistyczny W Siedlcach
Uniwersytet Medyczny W Lublinie
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Application filed by Uniwersytet Medyczny W Białymstoku, Uniwersytet Przyrodniczo-Humanistyczny W Siedlcach, Uniwersytet Medyczny W LubliniefiledCriticalUniwersytet Medyczny W Białymstoku
Priority to PL427993ApriorityCriticalpatent/PL237894B1/en
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Publication of PL237894B1publicationCriticalpatent/PL237894B1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Nitrogen Condensed Heterocyclic Rings
(AREA)
Abstract
Przedmiotem zgłoszenia są achiralne pochodne sulfonamidowe 5-fenylo-7-metylo-pirazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazyny. Związki te wykazują aktywność przeciwnowotworową, cytostatyczną, cytotoksyczną i antyproliferacyjną. Przedmiotem zgłoszenia jest także sposób wytwarzania pochodnych sulfonamidowych 5-fenylo-7-metylo-pirazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazyny oraz zastosowania takich związków i kompozycja farmaceutyczna je zawierająca.The subject of the application are 5-phenyl-7-methyl-pyrazolo [4,3-e] tetrazolo [4,5-b] [1,2,4] triazine achiral sulfonamide derivatives. These compounds exhibit antitumor, cytostatic, cytotoxic and antiproliferative activity. The subject of the application is also a process for the preparation of 5-phenyl-7-methyl-pyrazolo [4,3-e] tetrazolo [4,5-b] [1,2,4] triazine sulfonamide derivatives and the use of such compounds and a pharmaceutical composition containing them.
PL427993A2018-11-302018-11-30New sulfonamide derivatives of 5-phenyl-7-methyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine, method of their preparation, their uses and a pharmaceutical composition containing them
PL237894B1
(en)
New sulfonamide derivatives of 5-phenyl-7-methyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine, method of their preparation, their uses and a pharmaceutical composition containing them
New sulfonamide derivatives of 5-phenyl-7-methyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine, method of their preparation, their uses and a pharmaceutical composition containing them
New sulfonamide derivatives of 5-phenyl-7-methyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine, method of their preparation, their uses and a pharmaceutical composition containing them
Compounds derived from pyrimidin pyrido with modulating activity of smn2 genetic splicing; Pharmaceutical composition and use in the treatment of spinal muscular atrophy (ame).
2,4,6,7-tetrahydro-pyrazolo[4,3-d]pyrimidin-5-one derivatives and related compounds as c5a receptor modulators for treating vasculitis and inflammatory diseases
New sulfonamide derivatives of 5-phenyl-7-methyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine, method of their preparation, their uses and a pharmaceutical composition containing them
Chiral sulfonamide derivatives of 5-phenyl-7-methyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine, method of their preparation, their uses and a pharmaceutical composition containing a chiral sulfonamide derivative of 5-phenyl-7-methyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine