PL427994A1 - Chiral sulfonamide derivatives of 5-phenyl-7-methyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine, method of their preparation, their uses and a pharmaceutical composition containing a chiral sulfonamide derivative of 5-phenyl-7-methyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine - Google Patents
Chiral sulfonamide derivatives of 5-phenyl-7-methyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine, method of their preparation, their uses and a pharmaceutical composition containing a chiral sulfonamide derivative of 5-phenyl-7-methyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazineInfo
- Publication number
- PL427994A1 PL427994A1 PL427994A PL42799418A PL427994A1 PL 427994 A1 PL427994 A1 PL 427994A1 PL 427994 A PL427994 A PL 427994A PL 42799418 A PL42799418 A PL 42799418A PL 427994 A1 PL427994 A1 PL 427994A1
- Authority
- PL
- Poland
- Prior art keywords
- tetrazolo
- pyrazolo
- phenyl
- methyl
- triazine
- Prior art date
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Przedmiotem wynalazku są chiralne pochodne sulfonamidowe 5-fenylo-7-metylo-pirazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazyny przedstawione ogólnym wzorem 1. Związki które wykazują aktywność przeciwnowotworową, cytostatyczną, cytotoksyczną i antyproliferacyjną. Przedmiotem wynalazku jest także sposób wytwarzania chiralnych sulfonamidowych pochodnych 5-fenylo-7-metylo-pirazolo[4,3-e]tetrazolo[4,5-b][1,2,4] triazyny o ogólnym wzorze 1, a także zastosowania takich związków i kompozycja farmaceutyczna je zawierająca.The subject of the invention are chiral sulfonamide derivatives 5-phenyl-7-methyl-pyrazolo [4,3-e] tetrazolo [4,5-b] [1,2,4] triazines represented by the general formula 1. Compounds that show antitumor, cytostatic activity , cytotoxic and antiproliferative. The invention also relates to a process for the preparation of chiral sulfonamide derivatives of 5-phenyl-7-methyl-pyrazolo [4,3-e] tetrazolo [4,5-b] [1,2,4] triazine of the general formula I, as well as the use of such the compounds and a pharmaceutical composition containing them.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL427994A PL237895B1 (en) | 2018-11-30 | 2018-11-30 | Chiral sulfonamide derivatives of 5-phenyl-7-methyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine, method of their preparation, their uses and a pharmaceutical composition containing a chiral sulfonamide derivative of 5-phenyl-7-methyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL427994A PL237895B1 (en) | 2018-11-30 | 2018-11-30 | Chiral sulfonamide derivatives of 5-phenyl-7-methyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine, method of their preparation, their uses and a pharmaceutical composition containing a chiral sulfonamide derivative of 5-phenyl-7-methyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine |
Publications (2)
Publication Number | Publication Date |
---|---|
PL427994A1 true PL427994A1 (en) | 2020-06-01 |
PL237895B1 PL237895B1 (en) | 2021-06-14 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL427994A PL237895B1 (en) | 2018-11-30 | 2018-11-30 | Chiral sulfonamide derivatives of 5-phenyl-7-methyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine, method of their preparation, their uses and a pharmaceutical composition containing a chiral sulfonamide derivative of 5-phenyl-7-methyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine |
Country Status (1)
Country | Link |
---|---|
PL (1) | PL237895B1 (en) |
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2018
- 2018-11-30 PL PL427994A patent/PL237895B1/en unknown
Also Published As
Publication number | Publication date |
---|---|
PL237895B1 (en) | 2021-06-14 |
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PL427994A1 (en) | Chiral sulfonamide derivatives of 5-phenyl-7-methyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine, method of their preparation, their uses and a pharmaceutical composition containing a chiral sulfonamide derivative of 5-phenyl-7-methyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine |