PL421041A1 - 7,4'-dipentoxy-naringenin-oxime and method for obtaining 7,4'-dipentoxy-naringenin-oxime - Google Patents
7,4'-dipentoxy-naringenin-oxime and method for obtaining 7,4'-dipentoxy-naringenin-oximeInfo
- Publication number
- PL421041A1 PL421041A1 PL421041A PL42104117A PL421041A1 PL 421041 A1 PL421041 A1 PL 421041A1 PL 421041 A PL421041 A PL 421041A PL 42104117 A PL42104117 A PL 42104117A PL 421041 A1 PL421041 A1 PL 421041A1
- Authority
- PL
- Poland
- Prior art keywords
- oxime
- dipentoxy
- naringenin
- obtaining
- formula
- Prior art date
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- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Przedmiotem zgłoszenia jest oksym 7,4'-dipentoksynaringeniny o wzorze 2 oraz sposób otrzymywania tego związku. Sposób ten polega na tym, że do substratu, którym jest 7,4'-dipentoksynaringenina o wzorze 1 dodaje się chlorowodorek hydroksyloaminy oraz bezwodny octan sodu w stosunku molowym co najmniej 1:1,5:1,5 oraz minimalną ilość alkoholu, co stanowi mieszaninę reakcyjną, którą zabezpiecza się przed dostępem światła i pozostawia w temperaturze od 45°C do 55°C na okres od 48 do 72 godzin przy ciągłym mieszaniu, po czym mieszaninę wylewa się do wody z lodem, wytrącony osad sączy się pod zmniejszonym ciśnieniem, a następnie otrzymany surowy produkt oczyszcza się.The subject of the application is 7,4'-dipentoxynaringenin oxime of formula 2 and the method of obtaining this compound. This method consists in adding hydroxylamine hydrochloride and anhydrous sodium acetate in a molar ratio of at least 1: 1.5: 1.5 and a minimum amount of alcohol to the substrate, which is 7,4'-dipentoxynaringenine of formula 1 the reaction mixture, which is protected from light and left at a temperature of 45 ° C to 55 ° C for 48 to 72 hours with continuous stirring, after which the mixture is poured into ice-water, the precipitate is filtered under reduced pressure, and then the obtained crude product is purified.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL421041A PL236843B1 (en) | 2017-03-29 | 2017-03-29 | 7,4'-dipentoxy-naringenin-oxime and method for obtaining 7,4'-dipentoxy-naringenin-oxime |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL421041A PL236843B1 (en) | 2017-03-29 | 2017-03-29 | 7,4'-dipentoxy-naringenin-oxime and method for obtaining 7,4'-dipentoxy-naringenin-oxime |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL421041A1 true PL421041A1 (en) | 2018-10-08 |
| PL236843B1 PL236843B1 (en) | 2021-02-22 |
Family
ID=63688113
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL421041A PL236843B1 (en) | 2017-03-29 | 2017-03-29 | 7,4'-dipentoxy-naringenin-oxime and method for obtaining 7,4'-dipentoxy-naringenin-oxime |
Country Status (1)
| Country | Link |
|---|---|
| PL (1) | PL236843B1 (en) |
-
2017
- 2017-03-29 PL PL421041A patent/PL236843B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL236843B1 (en) | 2021-02-22 |
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