PL4182311T3 - Pochodne 1-metylo-1h-pirazol-3-ilu do zastosowania w leczeniu chorób neowaskularnych - Google Patents

Pochodne 1-metylo-1h-pirazol-3-ilu do zastosowania w leczeniu chorób neowaskularnych

Info

Publication number
PL4182311T3
PL4182311T3 PL21748927.7T PL21748927T PL4182311T3 PL 4182311 T3 PL4182311 T3 PL 4182311T3 PL 21748927 T PL21748927 T PL 21748927T PL 4182311 T3 PL4182311 T3 PL 4182311T3
Authority
PL
Poland
Prior art keywords
pyrazol
derivatives
methyl
treatment
neovascular diseases
Prior art date
Application number
PL21748927.7T
Other languages
English (en)
Inventor
Andrew Douglas Baxter
Jonathan Morris
Original Assignee
Exonate Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exonate Limited filed Critical Exonate Limited
Publication of PL4182311T3 publication Critical patent/PL4182311T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/396Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having three-membered rings, e.g. aziridine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL21748927.7T 2020-07-14 2021-07-14 Pochodne 1-metylo-1h-pirazol-3-ilu do zastosowania w leczeniu chorób neowaskularnych PL4182311T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB2010829.6A GB202010829D0 (en) 2020-07-14 2020-07-14 Compounds for treatment of neovascular diseases
PCT/GB2021/051810 WO2022013555A1 (en) 2020-07-14 2021-07-14 1-methyl-1h-pyrazol-3-yl derivatives for use in the treatment of neovascular diseases

Publications (1)

Publication Number Publication Date
PL4182311T3 true PL4182311T3 (pl) 2025-11-12

Family

ID=72139988

Family Applications (1)

Application Number Title Priority Date Filing Date
PL21748927.7T PL4182311T3 (pl) 2020-07-14 2021-07-14 Pochodne 1-metylo-1h-pirazol-3-ilu do zastosowania w leczeniu chorób neowaskularnych

Country Status (23)

Country Link
US (2) US12024504B2 (pl)
EP (1) EP4182311B1 (pl)
JP (1) JP2023535157A (pl)
KR (1) KR20230052890A (pl)
CN (1) CN116075506B (pl)
AU (1) AU2021309894A1 (pl)
BR (1) BR112023000571A2 (pl)
CA (1) CA3183466A1 (pl)
DK (1) DK4182311T3 (pl)
ES (1) ES3039003T3 (pl)
FI (1) FI4182311T3 (pl)
GB (1) GB202010829D0 (pl)
HR (1) HRP20250955T1 (pl)
HU (1) HUE072558T2 (pl)
LT (1) LT4182311T (pl)
MX (1) MX2023000570A (pl)
PL (1) PL4182311T3 (pl)
PT (1) PT4182311T (pl)
RS (1) RS67158B1 (pl)
SI (1) SI4182311T1 (pl)
SM (1) SMT202500307T1 (pl)
WO (1) WO2022013555A1 (pl)
ZA (1) ZA202301105B (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202010829D0 (en) * 2020-07-14 2020-08-26 Exonate Ltd Compounds for treatment of neovascular diseases
WO2024155864A1 (en) * 2023-01-20 2024-07-25 Allianthera (Suzhou) Biopharmaceutical Co., Ltd. Sprk1 inhibitors and methods of use

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE462006T1 (de) 2001-08-01 2010-04-15 Univ Bristol Isoform des vegfs
EP1712242B1 (en) 2003-12-26 2018-05-30 Masatoshi Hagiwara Method of regulating phosphorylation of sr protein and antiviral agents comprising sr protein activity regulator as the active ingredient
CA2649043C (en) * 2006-04-19 2013-09-17 Astellas Pharma Inc. Azolecarboxamide derivative
GB0704678D0 (en) 2007-03-09 2007-04-18 Univ Bristol Pro- and anti-angiogenic treatments
GB0803912D0 (en) 2008-02-29 2008-05-07 Univ Bristol Novel Uses of VEGFxxxb
EP2358382A2 (en) 2008-11-22 2011-08-24 The University of Bristol NOVEL USES OF VEGFxxxB
GB201009173D0 (en) 2010-05-28 2010-07-14 Univ Bristol Treatment of pain
JP2016504270A (ja) * 2012-10-17 2016-02-12 ザ ユニバーシティ オブ ブリストル 眼血管形成(ocularneovasculan)を治療するのに有用な化合物
GB201406956D0 (en) 2014-04-17 2014-06-04 Univ Nottingham Compounds
GB201518365D0 (en) * 2015-10-16 2015-12-02 Exonate Ltd Compounds
JOP20170147B1 (ar) * 2016-07-07 2021-08-17 Salvat Lab Sa تركيبة عينية تشتمل على زيت الخروع ودهون ثلاثية متوسطة السلسلة
JP7261793B2 (ja) 2017-09-27 2023-04-20 エクソネイト リミテッド Srpk1阻害剤
CN110710099B (zh) 2017-09-29 2024-02-02 株式会社日立产机系统 数据获取方法、逆变器和旋转电机
GB202010829D0 (en) * 2020-07-14 2020-08-26 Exonate Ltd Compounds for treatment of neovascular diseases

Also Published As

Publication number Publication date
US20240300929A1 (en) 2024-09-12
MX2023000570A (es) 2023-04-19
ES3039003T3 (en) 2025-10-16
HRP20250955T1 (hr) 2025-10-10
CN116075506A (zh) 2023-05-05
LT4182311T (lt) 2025-09-25
PT4182311T (pt) 2025-08-27
US20220411412A1 (en) 2022-12-29
GB202010829D0 (en) 2020-08-26
WO2022013555A1 (en) 2022-01-20
SI4182311T1 (sl) 2025-11-28
KR20230052890A (ko) 2023-04-20
RS67158B1 (sr) 2025-09-30
EP4182311A1 (en) 2023-05-24
ZA202301105B (en) 2025-07-30
DK4182311T3 (da) 2025-08-25
US12024504B2 (en) 2024-07-02
JP2023535157A (ja) 2023-08-16
SMT202500307T1 (it) 2025-11-10
CN116075506B (zh) 2025-10-10
FI4182311T3 (fi) 2025-08-22
EP4182311B1 (en) 2025-06-04
CA3183466A1 (en) 2022-01-20
HUE072558T2 (hu) 2025-11-28
AU2021309894A1 (en) 2023-03-09
BR112023000571A2 (pt) 2023-01-31

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