GB201009173D0 - Treatment of pain - Google Patents
Treatment of painInfo
- Publication number
- GB201009173D0 GB201009173D0 GBGB1009173.4A GB201009173A GB201009173D0 GB 201009173 D0 GB201009173 D0 GB 201009173D0 GB 201009173 A GB201009173 A GB 201009173A GB 201009173 D0 GB201009173 D0 GB 201009173D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- vegfr2
- vegfxxx
- isoforms
- agonist
- pain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1858—Platelet-derived growth factor [PDGF]
- A61K38/1866—Vascular endothelial growth factor [VEGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Abstract
The invention provides an active agent comprising one or more VEGFR2 agonist for use in treating or preventing VEGFR2-mediated non-inflammatory pain. The VEGFR2 agonist may be selected from the VEGFxxxb family of proteins, particularly VEGF165b, soluble VEGF receptors having activity as inhibitors of VEGFR2 antagonists and VEGFxxx isoforms that have the C-terminal hexapeptide corresponding to expression immediately after exon 7, or VEGFxxx isoforms that lack neuropilin binding mediating portions of the amino acid sequence.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1009173.4A GB201009173D0 (en) | 2010-05-28 | 2010-05-28 | Treatment of pain |
PCT/GB2011/051018 WO2011148200A1 (en) | 2010-05-28 | 2011-05-27 | Treatment of pain |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1009173.4A GB201009173D0 (en) | 2010-05-28 | 2010-05-28 | Treatment of pain |
Publications (1)
Publication Number | Publication Date |
---|---|
GB201009173D0 true GB201009173D0 (en) | 2010-07-14 |
Family
ID=42371319
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GBGB1009173.4A Ceased GB201009173D0 (en) | 2010-05-28 | 2010-05-28 | Treatment of pain |
Country Status (2)
Country | Link |
---|---|
GB (1) | GB201009173D0 (en) |
WO (1) | WO2011148200A1 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IN2015DN03969A (en) | 2012-10-17 | 2015-10-02 | Univ Bristol | |
GB201406956D0 (en) | 2014-04-17 | 2014-06-04 | Univ Nottingham | Compounds |
GB201518365D0 (en) | 2015-10-16 | 2015-12-02 | Exonate Ltd | Compounds |
JP7261793B2 (en) | 2017-09-27 | 2023-04-20 | エクソネイト リミテッド | SRPK1 inhibitor |
GB202010829D0 (en) | 2020-07-14 | 2020-08-26 | Exonate Ltd | Compounds for treatment of neovascular diseases |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030236214A1 (en) * | 1999-06-09 | 2003-12-25 | Wolff Jon A. | Charge reversal of polyion complexes and treatment of peripheral occlusive disease |
WO2003012105A2 (en) | 2001-08-01 | 2003-02-13 | University Of Bristol | Vegf isoform |
GB0704678D0 (en) | 2007-03-09 | 2007-04-18 | Univ Bristol | Pro- and anti-angiogenic treatments |
GB0803912D0 (en) | 2008-02-29 | 2008-05-07 | Univ Bristol | Novel Uses of VEGFxxxb |
-
2010
- 2010-05-28 GB GBGB1009173.4A patent/GB201009173D0/en not_active Ceased
-
2011
- 2011-05-27 WO PCT/GB2011/051018 patent/WO2011148200A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2011148200A1 (en) | 2011-12-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AT | Applications terminated before publication under section 16(1) |