PL4178579T3 - 5-amino-2,3-dihydro-1,4-fthalazynodion jako środek oszczędzający glikokortykoidy - Google Patents
5-amino-2,3-dihydro-1,4-fthalazynodion jako środek oszczędzający glikokortykoidyInfo
- Publication number
- PL4178579T3 PL4178579T3 PL21755360.1T PL21755360T PL4178579T3 PL 4178579 T3 PL4178579 T3 PL 4178579T3 PL 21755360 T PL21755360 T PL 21755360T PL 4178579 T3 PL4178579 T3 PL 4178579T3
- Authority
- PL
- Poland
- Prior art keywords
- phthalazinedione
- glucocorticoid
- dihydro
- amino
- sparing agent
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/502—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20000248 | 2020-07-09 | ||
| PCT/EP2021/000078 WO2022008093A1 (en) | 2020-07-09 | 2021-07-08 | Glucocorticoid-sparing agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL4178579T3 true PL4178579T3 (pl) | 2025-08-11 |
Family
ID=71574915
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL21755360.1T PL4178579T3 (pl) | 2020-07-09 | 2021-07-08 | 5-amino-2,3-dihydro-1,4-fthalazynodion jako środek oszczędzający glikokortykoidy |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20230241060A1 (pl) |
| EP (1) | EP4178579B1 (pl) |
| JP (1) | JP2023532972A (pl) |
| KR (1) | KR20230038228A (pl) |
| CN (1) | CN115916258A (pl) |
| AU (1) | AU2021304254B9 (pl) |
| BR (1) | BR112023000287A2 (pl) |
| CA (1) | CA3183225A1 (pl) |
| ES (1) | ES3029560T3 (pl) |
| HU (1) | HUE071698T2 (pl) |
| IL (1) | IL299528A (pl) |
| MX (1) | MX2023000351A (pl) |
| NZ (1) | NZ796371A (pl) |
| PH (1) | PH12022553236A1 (pl) |
| PL (1) | PL4178579T3 (pl) |
| WO (1) | WO2022008093A1 (pl) |
| ZA (1) | ZA202300309B (pl) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11918570B2 (en) | 2020-04-13 | 2024-03-05 | The Research Foundation For The State University Of New York | Method of treatment for prevention of glucocorticoid toxicity and/or enhancement of muscle regeneration via neutrophil elastase inhibition |
| AU2023204891A1 (en) * | 2022-01-07 | 2024-08-08 | Metriopharm Ag | Use of 5-amino-2,3-dihydro-1,4-phthalazinedione in the treatment of congenital muscular dystrophies |
| WO2024117793A1 (ko) | 2022-12-02 | 2024-06-06 | 주식회사 엘지에너지솔루션 | 배터리 팩 및 그의 제조 방법 |
| EP4483879A1 (en) | 2023-06-29 | 2025-01-01 | MetrioPharm AG | 5-amino-2,3-dihydro-1,4-phthalazinedione for the prophylaxis and treatment of thrombotic disorders |
| WO2025029582A2 (en) * | 2023-08-01 | 2025-02-06 | Rubicon Scientific, Llc | Maintaining diethylcarbamazine in an extruded daily ration animal feed product |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2132188C1 (ru) * | 1998-11-03 | 1999-06-27 | Закрытое акционерное общество "Абидофф-Фарма" | Способ лечения гипофункции щитовидной железы |
| US7326690B2 (en) | 2002-10-30 | 2008-02-05 | Bach Pharma, Inc. | Modulation of cell fates and activities by phthalazinediones |
| US6953799B1 (en) | 2002-10-30 | 2005-10-11 | Bach Pharma, Inc. | Modulation of cell fates and activities by diketo phthalazines |
| PL231885B1 (pl) | 2009-01-16 | 2019-04-30 | Abidopharma Spolka Z Ograniczona Odpowiedzialnoscia | Sposób wytwarzania soli 5-amino-2,3-dihydroftalazyno-1,4-di onu z metalami alkalicznymi, ich kompozycje farmaceutyczne i ich zastosowanie |
| HRP20140752T1 (hr) * | 2010-03-01 | 2014-10-24 | Metriopharm Ag | Kristalni oblici 5-amino-2,3-dihidroftalazin-1,4-dion natrijeve soli, farmaceutski pripravci koji ih sadrže i postupak za njihovu proizvodnju |
| US9464079B2 (en) | 2011-03-23 | 2016-10-11 | Semorex Technologies Ltd. | Treatment of proliferative disorders with a chemiluminescent agent |
| WO2016096143A1 (de) | 2014-12-18 | 2016-06-23 | Metriopharm Ag | Kristalline form von 5-amino-2,3-dihydrophthalazin-1,4-dion natriumsalz, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung |
| EP3248602A1 (en) * | 2016-05-26 | 2017-11-29 | MetrioPharm AG | Use of 5-amino-2,3-dihydro-1,4-phthalazinedione in the treatment of inflammatory and/or degenerative disorders of the tendons, ligaments of the joints, articular capsules and bursae |
| US11007192B2 (en) * | 2016-11-07 | 2021-05-18 | Metriopharm Ag | Use of 5-amino-2,3-dihydro-1,4-phthalazinedione in the treatment of chronic progressive multiple sclerosis |
-
2021
- 2021-07-08 US US18/004,806 patent/US20230241060A1/en active Pending
- 2021-07-08 JP JP2023500092A patent/JP2023532972A/ja active Pending
- 2021-07-08 MX MX2023000351A patent/MX2023000351A/es unknown
- 2021-07-08 PH PH1/2022/553236A patent/PH12022553236A1/en unknown
- 2021-07-08 IL IL299528A patent/IL299528A/en unknown
- 2021-07-08 CN CN202180049059.8A patent/CN115916258A/zh active Pending
- 2021-07-08 WO PCT/EP2021/000078 patent/WO2022008093A1/en not_active Ceased
- 2021-07-08 AU AU2021304254A patent/AU2021304254B9/en active Active
- 2021-07-08 ES ES21755360T patent/ES3029560T3/es active Active
- 2021-07-08 CA CA3183225A patent/CA3183225A1/en active Pending
- 2021-07-08 HU HUE21755360A patent/HUE071698T2/hu unknown
- 2021-07-08 NZ NZ796371A patent/NZ796371A/en unknown
- 2021-07-08 PL PL21755360.1T patent/PL4178579T3/pl unknown
- 2021-07-08 BR BR112023000287A patent/BR112023000287A2/pt unknown
- 2021-07-08 KR KR1020237004403A patent/KR20230038228A/ko active Pending
- 2021-07-08 EP EP21755360.1A patent/EP4178579B1/en active Active
-
2023
- 2023-01-06 ZA ZA2023/00309A patent/ZA202300309B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2023532972A (ja) | 2023-08-01 |
| HUE071698T2 (hu) | 2025-09-28 |
| AU2021304254B2 (en) | 2025-06-26 |
| CA3183225A1 (en) | 2022-01-13 |
| NZ796371A (en) | 2026-01-30 |
| PH12022553236A1 (en) | 2024-02-12 |
| ZA202300309B (en) | 2024-05-30 |
| EP4178579B1 (en) | 2025-02-12 |
| US20230241060A1 (en) | 2023-08-03 |
| BR112023000287A2 (pt) | 2023-01-31 |
| EP4178579C0 (en) | 2025-02-12 |
| MX2023000351A (es) | 2023-05-19 |
| EP4178579A1 (en) | 2023-05-17 |
| ES3029560T3 (en) | 2025-06-24 |
| AU2021304254B9 (en) | 2025-07-10 |
| IL299528A (en) | 2023-02-01 |
| AU2021304254A1 (en) | 2023-02-16 |
| KR20230038228A (ko) | 2023-03-17 |
| CN115916258A (zh) | 2023-04-04 |
| WO2022008093A1 (en) | 2022-01-13 |
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