PL417694A1 - α-aminophosphonic acids originating from acetylpyridine and method for producing it - Google Patents
α-aminophosphonic acids originating from acetylpyridine and method for producing itInfo
- Publication number
- PL417694A1 PL417694A1 PL417694A PL41769416A PL417694A1 PL 417694 A1 PL417694 A1 PL 417694A1 PL 417694 A PL417694 A PL 417694A PL 41769416 A PL41769416 A PL 41769416A PL 417694 A1 PL417694 A1 PL 417694A1
- Authority
- PL
- Poland
- Prior art keywords
- acetylpyridine
- aminophosphonic acids
- producing
- bromotrimethylsilane
- reacted
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 3
- 150000007513 acids Chemical class 0.000 title abstract 3
- AJKVQEKCUACUMD-UHFFFAOYSA-N 2-Acetylpyridine Chemical compound CC(=O)C1=CC=CC=N1 AJKVQEKCUACUMD-UHFFFAOYSA-N 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical group C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- IYYIVELXUANFED-UHFFFAOYSA-N bromo(trimethyl)silane Chemical compound C[Si](C)(C)Br IYYIVELXUANFED-UHFFFAOYSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- CYTQBVOFDCPGCX-UHFFFAOYSA-N trimethyl phosphite Chemical compound COP(OC)OC CYTQBVOFDCPGCX-UHFFFAOYSA-N 0.000 abstract 2
- 238000011065 in-situ storage Methods 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- -1 pyridine ketimines Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- VMZOBROUFBEGAR-UHFFFAOYSA-N tris(trimethylsilyl) phosphite Chemical compound C[Si](C)(C)OP(O[Si](C)(C)C)O[Si](C)(C)C VMZOBROUFBEGAR-UHFFFAOYSA-N 0.000 abstract 1
Abstract
Przedmiotem zgłoszenia są kwasy ?-aminofosfonowe pochodne acetylopirydyny o wzorze ogólnym 1, w którym Het oznacza pierścień pirydynowy podstawiony w pozycji 2, 3 lub 4 oraz sposób ich wytwarzania. Sposób charakteryzuje się tym, że w pierwszym etapie bromotrimetylosilan poddaje się reakcji z fosforynem trimetylowym przy stosunku molowym bromotrimetylosilanu do fosforynu trimetylowego równym 4 do 1, a wytworzony in situ fosforyn tris(trimetylosilylowy) poddaje się następnie reakcji addycji z ketiminami pirydynowymi, a potem odparowuje się rozpuszczalnik i pozostałość rozpuszcza się w alkoholu metylowym, z którego wydziela się pożądane kwasy ?-aminofosfonowe.The subject of the application are α-aminophosphonic acids of acetylpyridine of general formula 1, in which Het is a pyridine ring substituted in the 2, 3 or 4 position and the method of their preparation. The method is characterized in that in the first stage bromotrimethylsilane is reacted with trimethyl phosphite at a molar ratio of bromotrimethylsilane to trimethyl phosphite equal to 4 to 1, and the in situ formed tris (trimethylsilyl) phosphite is then reacted with pyridine ketimines and then evaporated the solvent and residue are dissolved in methyl alcohol, from which the desired α-aminophosphonic acids are separated.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL417694A PL231475B1 (en) | 2016-06-23 | 2016-06-23 | α-aminophosphonic acids originating from acetylpyridine and method for producing it |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL417694A PL231475B1 (en) | 2016-06-23 | 2016-06-23 | α-aminophosphonic acids originating from acetylpyridine and method for producing it |
Publications (2)
Publication Number | Publication Date |
---|---|
PL417694A1 true PL417694A1 (en) | 2017-02-27 |
PL231475B1 PL231475B1 (en) | 2019-02-28 |
Family
ID=58092013
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL417694A PL231475B1 (en) | 2016-06-23 | 2016-06-23 | α-aminophosphonic acids originating from acetylpyridine and method for producing it |
Country Status (1)
Country | Link |
---|---|
PL (1) | PL231475B1 (en) |
-
2016
- 2016-06-23 PL PL417694A patent/PL231475B1/en unknown
Also Published As
Publication number | Publication date |
---|---|
PL231475B1 (en) | 2019-02-28 |
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