PL4119153T3 - Terapie ukierunkowane na cd47 w leczeniu choroby zakaźnej - Google Patents

Terapie ukierunkowane na cd47 w leczeniu choroby zakaźnej

Info

Publication number
PL4119153T3
PL4119153T3 PL22185801.2T PL22185801T PL4119153T3 PL 4119153 T3 PL4119153 T3 PL 4119153T3 PL 22185801 T PL22185801 T PL 22185801T PL 4119153 T3 PL4119153 T3 PL 4119153T3
Authority
PL
Poland
Prior art keywords
treatment
infectious disease
targeted therapies
therapies
targeted
Prior art date
Application number
PL22185801.2T
Other languages
English (en)
Inventor
Kipp WEISKOPF
Kim J. HASENKRUG
Cheryl A. Stoddart
Joseph M. Mccune
Irving L. Weissman
Original Assignee
The Board Of Trustees Of The Leland Stanford Junior University
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services
The Regents Of The University Of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Board Of Trustees Of The Leland Stanford Junior University, The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, The Regents Of The University Of California filed Critical The Board Of Trustees Of The Leland Stanford Junior University
Publication of PL4119153T3 publication Critical patent/PL4119153T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Radiation-Therapy Devices (AREA)
PL22185801.2T 2013-02-05 2014-02-05 Terapie ukierunkowane na cd47 w leczeniu choroby zakaźnej PL4119153T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361761133P 2013-02-05 2013-02-05

Publications (1)

Publication Number Publication Date
PL4119153T3 true PL4119153T3 (pl) 2024-09-02

Family

ID=51300110

Family Applications (2)

Application Number Title Priority Date Filing Date
PL22185801.2T PL4119153T3 (pl) 2013-02-05 2014-02-05 Terapie ukierunkowane na cd47 w leczeniu choroby zakaźnej
PL20163565.3T PL3721888T3 (pl) 2013-02-05 2014-02-05 Terapie ukierunkowane na cd47 w leczeniu choroby zakaźnej

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL20163565.3T PL3721888T3 (pl) 2013-02-05 2014-02-05 Terapie ukierunkowane na cd47 w leczeniu choroby zakaźnej

Country Status (10)

Country Link
US (6) US9771428B2 (pl)
EP (4) EP3311824B1 (pl)
CA (1) CA2900256C (pl)
DK (1) DK3311824T3 (pl)
ES (4) ES2794700T3 (pl)
HR (1) HRP20200565T1 (pl)
PL (2) PL4119153T3 (pl)
PT (1) PT3721888T (pl)
SI (1) SI3721888T1 (pl)
WO (1) WO2014124028A1 (pl)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3311824B1 (en) 2013-02-05 2020-03-25 The Board of Trustees of the Leland Stanford Junior University Cd47 targeted therapies for the treatment of infectious disease
ES2765483T3 (es) 2013-09-18 2020-06-09 Univ Leland Stanford Junior Modulación de las vías de eferocitosis para el tratamiento de una enfermedad aterosclerótica
ES2838925T3 (es) * 2015-02-27 2021-07-02 Univ Leland Stanford Junior Terapia de combinación para el tratamiento de la ateroesclerosis
DK3298043T3 (da) * 2015-05-18 2021-02-15 Ab Initio Biotherapeutics Inc SIRP-polypeptidsammensætninger og fremgangsmåder til anvendelse
RU2740672C2 (ru) 2015-08-07 2021-01-19 ЭйЭлЭкс Онколоджи Инк. Конструкции, имеющие sirp-альфа домен или его вариант
US12344669B2 (en) 2016-06-17 2025-07-01 Changchun Genescience Pharmaceutical Co., Ltd. Anti-CD47 monoclonal antibody and use thereof
CN106084052B (zh) * 2016-06-17 2019-12-27 长春金赛药业股份有限公司 抗cd47单克隆抗体及其应用
JOP20190009A1 (ar) 2016-09-21 2019-01-27 Alx Oncology Inc أجسام مضادة ضد بروتين ألفا منظم للإشارات وطرق استخدامها
EP3532497B1 (en) 2016-10-26 2024-07-24 The Board of Trustees of the Leland Stanford Junior University Modified immunoglobulin hinge regions to reduce hemagglutination
CN110325549B (zh) 2016-12-09 2024-03-08 艾利妥 抗SIRPα抗体及其使用方法
US11319360B2 (en) 2016-12-29 2022-05-03 Korea Institute Of Science And Technology Exosome-based anticancer agent
WO2019022600A1 (en) 2017-07-24 2019-01-31 Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis TREATMENT OF PATHOLOGICAL CONDITIONS BY DIRECT AND INDIRECT TARGETING OF SIRPA INTERACTION - CD47
EP3658589B1 (en) 2017-07-26 2023-09-27 Forty Seven, Inc. Anti-sirp-alpha antibodies and related methods
MX2020001309A (es) 2017-08-02 2020-08-20 Phanes Therapeutics Inc Anticuerpos anti-cd47 y sus usos.
AR113862A1 (es) 2017-12-01 2020-06-17 Seattle Genetics Inc Anticuerpos anti-cd47 y sus usos para tratar cáncer
WO2019183266A1 (en) 2018-03-21 2019-09-26 ALX Oncology Inc. Antibodies against signal-regulatory protein alpha and methods of use
GB201807945D0 (en) 2018-05-16 2018-06-27 Ospedale San Raffaele Srl Vector production
CR20200566A (es) 2018-05-25 2021-02-19 Alector Llc Anticuerpos anti-sirpa y metodos de utilización de los mismos
SG11202102851XA (en) 2018-09-27 2021-04-29 Celgene Corp SIRPa BINDING PROTEINS AND METHODS OF USE THEREOF
US12331320B2 (en) 2018-10-10 2025-06-17 The Research Foundation For The State University Of New York Genome edited cancer cell vaccines
GB2593632B8 (en) * 2018-10-29 2026-07-08 Umc Utrecht Holding Bv IGA mediated killing of aberrant cells by CD47-Sirpalpha checkpoint inhibition of neutrophils
CA3141130A1 (en) 2019-05-31 2020-12-03 ALX Oncology Inc. Methods of treating cancer with sirp alpha fc fusion in combination with an immune checkpoint inhibitor
EP3756688A1 (en) 2019-06-25 2020-12-30 Université de Nantes Inhibitor of surface protein (sp-d) / sirpa / shp2 pathway for use in the prevention and/or treatment of secondary infection
WO2021108693A1 (en) 2019-11-27 2021-06-03 ALX Oncology Inc. Combination therapies for treating cancer
JP2024520902A (ja) 2021-05-13 2024-05-27 エーエルエックス オンコロジー インコーポレイテッド がんを治療するための併用療法
KR102690136B1 (ko) * 2021-06-30 2024-07-31 연세대학교 산학협력단 바이러스 및 박테리아의 중복 감염 치료용 조성물
WO2025264856A1 (en) * 2024-06-19 2025-12-26 Whitehead Institute For Biomedical Research Antibody combinations for macrophage stimulation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8076494A (en) 1993-10-15 1995-05-04 Cytrx Corporation Therapeutic delivery compositions and methods of use thereof
US8377448B2 (en) 2006-05-15 2013-02-19 The Board Of Trustees Of The Leland Standford Junior University CD47 related compositions and methods for treating immunological diseases and disorders
EP2111869A1 (en) * 2008-04-23 2009-10-28 Stichting Sanquin Bloedvoorziening Compositions and methods to enhance the immune system
DK2429574T3 (da) * 2009-05-15 2015-06-22 Univ Health Network Sammensætninger og fremgangsmåder til behandling af hæmatologiske cancere der targeterer sirp-cd47-interaktionen
AU2011252851B2 (en) 2010-05-14 2016-10-06 The Board Of Trustees Of The Leland Stanford Junior University Humanized and chimeric monoclonal antibodies to CD47
EP3311824B1 (en) * 2013-02-05 2020-03-25 The Board of Trustees of the Leland Stanford Junior University Cd47 targeted therapies for the treatment of infectious disease

Also Published As

Publication number Publication date
ES2649165T3 (es) 2018-01-10
EP4119153C0 (en) 2024-04-24
WO2014124028A1 (en) 2014-08-14
US20230406952A1 (en) 2023-12-21
DK3311824T3 (da) 2020-04-14
SI3721888T1 (sl) 2023-04-28
US12410259B2 (en) 2025-09-09
PT3721888T (pt) 2022-11-02
US20220098322A1 (en) 2022-03-31
EP2953633A4 (en) 2016-09-14
US10723803B2 (en) 2020-07-28
EP2953633A1 (en) 2015-12-16
US20190092873A1 (en) 2019-03-28
HRP20200565T1 (hr) 2020-08-07
ES2983571T3 (es) 2024-10-23
ES2794700T3 (es) 2020-11-18
CA2900256A1 (en) 2014-08-14
US20200354469A1 (en) 2020-11-12
EP4119153A1 (en) 2023-01-18
EP3311824A1 (en) 2018-04-25
EP2953633B1 (en) 2017-10-04
US11230607B2 (en) 2022-01-25
PL3721888T3 (pl) 2023-04-11
US10184004B2 (en) 2019-01-22
EP3721888B1 (en) 2022-07-20
US20170362332A1 (en) 2017-12-21
EP3721888A1 (en) 2020-10-14
EP4119153B1 (en) 2024-04-24
US11780931B2 (en) 2023-10-10
US9771428B2 (en) 2017-09-26
CA2900256C (en) 2023-03-21
EP3311824B1 (en) 2020-03-25
US20150376288A1 (en) 2015-12-31
ES2928001T3 (es) 2022-11-14

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