PL4119153T3 - Terapie ukierunkowane na cd47 w leczeniu choroby zakaźnej - Google Patents

Terapie ukierunkowane na cd47 w leczeniu choroby zakaźnej

Info

Publication number
PL4119153T3
PL4119153T3 PL22185801.2T PL22185801T PL4119153T3 PL 4119153 T3 PL4119153 T3 PL 4119153T3 PL 22185801 T PL22185801 T PL 22185801T PL 4119153 T3 PL4119153 T3 PL 4119153T3
Authority
PL
Poland
Prior art keywords
treatment
infectious disease
targeted therapies
therapies
targeted
Prior art date
Application number
PL22185801.2T
Other languages
English (en)
Inventor
Kipp WEISKOPF
Kim J. HASENKRUG
Cheryl A. Stoddart
Joseph M. Mccune
Irving L. Weissman
Original Assignee
The Board Of Trustees Of The Leland Stanford Junior University
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services
The Regents Of The University Of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Board Of Trustees Of The Leland Stanford Junior University, The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, The Regents Of The University Of California filed Critical The Board Of Trustees Of The Leland Stanford Junior University
Publication of PL4119153T3 publication Critical patent/PL4119153T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Radiation-Therapy Devices (AREA)
PL22185801.2T 2013-02-05 2014-02-05 Terapie ukierunkowane na cd47 w leczeniu choroby zakaźnej PL4119153T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361761133P 2013-02-05 2013-02-05

Publications (1)

Publication Number Publication Date
PL4119153T3 true PL4119153T3 (pl) 2024-09-02

Family

ID=51300110

Family Applications (2)

Application Number Title Priority Date Filing Date
PL20163565.3T PL3721888T3 (pl) 2013-02-05 2014-02-05 Terapie ukierunkowane na cd47 w leczeniu choroby zakaźnej
PL22185801.2T PL4119153T3 (pl) 2013-02-05 2014-02-05 Terapie ukierunkowane na cd47 w leczeniu choroby zakaźnej

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL20163565.3T PL3721888T3 (pl) 2013-02-05 2014-02-05 Terapie ukierunkowane na cd47 w leczeniu choroby zakaźnej

Country Status (10)

Country Link
US (6) US9771428B2 (pl)
EP (4) EP3721888B1 (pl)
CA (1) CA2900256C (pl)
DK (1) DK3311824T3 (pl)
ES (4) ES2983571T3 (pl)
HR (1) HRP20200565T1 (pl)
PL (2) PL3721888T3 (pl)
PT (1) PT3721888T (pl)
SI (1) SI3721888T1 (pl)
WO (1) WO2014124028A1 (pl)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9771428B2 (en) * 2013-02-05 2017-09-26 The Board Of Trustees Of The Leland Stanford Junior University CD47 targeted therapies for the treatment of infectious disease
ES2765483T3 (es) 2013-09-18 2020-06-09 Univ Leland Stanford Junior Modulación de las vías de eferocitosis para el tratamiento de una enfermedad aterosclerótica
ES2941387T3 (es) * 2015-02-27 2023-05-22 Univ Leland Stanford Junior Terapia de combinación para el tratamiento de la ateroesclerosis
DK3298043T3 (da) * 2015-05-18 2021-02-15 Ab Initio Biotherapeutics Inc SIRP-polypeptidsammensætninger og fremgangsmåder til anvendelse
US10259859B2 (en) 2015-08-07 2019-04-16 ALX Oncology Inc. Constructs having a SIRP-α domain or variant thereof
CN106084052B (zh) * 2016-06-17 2019-12-27 长春金赛药业股份有限公司 抗cd47单克隆抗体及其应用
US12344669B2 (en) 2016-06-17 2025-07-01 Changchun Genescience Pharmaceutical Co., Ltd. Anti-CD47 monoclonal antibody and use thereof
JOP20190009A1 (ar) 2016-09-21 2019-01-27 Alx Oncology Inc أجسام مضادة ضد بروتين ألفا منظم للإشارات وطرق استخدامها
WO2018081448A1 (en) 2016-10-26 2018-05-03 The Board Of Trustees Of The Leland Stanford Junior University Modified immunoglobulin hinge regions to reduce hemagglutination
US11779642B2 (en) 2016-12-09 2023-10-10 Alector Llc Anti-SIRP-alpha antibodies and methods of use thereof
WO2018124835A1 (ko) 2016-12-29 2018-07-05 한국과학기술연구원 신규 엑소좀 계열 항암제
WO2019022600A1 (en) * 2017-07-24 2019-01-31 Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis TREATMENT OF PATHOLOGICAL CONDITIONS BY DIRECT AND INDIRECT TARGETING OF SIRPA INTERACTION - CD47
AU2018308364C1 (en) 2017-07-26 2023-02-16 Forty Seven, LLC Anti-SIRP-alpha antibodies and related methods
EP3661965A4 (en) 2017-08-02 2022-07-13 Phanes Therapeutics, Inc. ANTI-CD47 ANTIBODIES AND USES THEREOF
US11180552B2 (en) 2017-12-01 2021-11-23 Seagen Inc. CD47 antibodies and uses thereof for treating cancer
US11292850B2 (en) 2018-03-21 2022-04-05 ALX Oncology Inc. Antibodies against signal-regulatory protein α and methods of use
GB201807945D0 (en) 2018-05-16 2018-06-27 Ospedale San Raffaele Srl Vector production
JP7337099B2 (ja) 2018-05-25 2023-09-01 アレクトル エルエルシー 抗sirpa抗体およびその使用法
AU2019349651B2 (en) 2018-09-27 2023-12-07 Celgene Corporation SIRP alpha binding proteins and methods of use thereof
US11591390B2 (en) 2018-09-27 2023-02-28 Celgene Corporation SIRP-α binding proteins and methods of use thereof
US12331320B2 (en) 2018-10-10 2025-06-17 The Research Foundation For The State University Of New York Genome edited cancer cell vaccines
WO2020091596A1 (en) * 2018-10-29 2020-05-07 Umc Utrecht Holding B.V. Iga mediated killing of aberrant cells by cd47- sirpalpha checkpoint inhibition of neutrophils
CN119700933A (zh) 2019-05-31 2025-03-28 Alx肿瘤生物技术公司 用SIRPαFc融合体组合免疫检查点抑制剂治疗癌症的方法
EP3756688A1 (en) 2019-06-25 2020-12-30 Université de Nantes Inhibitor of surface protein (sp-d) / sirpa / shp2 pathway for use in the prevention and/or treatment of secondary infection
JP2024520902A (ja) 2021-05-13 2024-05-27 エーエルエックス オンコロジー インコーポレイテッド がんを治療するための併用療法
KR102690136B1 (ko) * 2021-06-30 2024-07-31 연세대학교 산학협력단 바이러스 및 박테리아의 중복 감염 치료용 조성물

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995010265A1 (en) * 1993-10-15 1995-04-20 Cytrx Corporation Therapeutic delivery compositions and methods of use thereof
US8377448B2 (en) 2006-05-15 2013-02-19 The Board Of Trustees Of The Leland Standford Junior University CD47 related compositions and methods for treating immunological diseases and disorders
EP2111869A1 (en) * 2008-04-23 2009-10-28 Stichting Sanquin Bloedvoorziening Compositions and methods to enhance the immune system
CA2761438C (en) 2009-05-15 2017-12-12 University Health Network Compositions and methods for treating hematologic cancers targeting the sirp.alpha.-cd47 interaction
JP6166177B2 (ja) * 2010-05-14 2017-07-19 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー Cd47に対するヒト化及びキメラモノクローナル抗体
US9771428B2 (en) * 2013-02-05 2017-09-26 The Board Of Trustees Of The Leland Stanford Junior University CD47 targeted therapies for the treatment of infectious disease

Also Published As

Publication number Publication date
EP4119153A1 (en) 2023-01-18
HRP20200565T1 (hr) 2020-08-07
US9771428B2 (en) 2017-09-26
US20230406952A1 (en) 2023-12-21
EP3311824B1 (en) 2020-03-25
DK3311824T3 (da) 2020-04-14
EP4119153B1 (en) 2024-04-24
US10723803B2 (en) 2020-07-28
EP3721888A1 (en) 2020-10-14
US12410259B2 (en) 2025-09-09
US20220098322A1 (en) 2022-03-31
US20200354469A1 (en) 2020-11-12
SI3721888T1 (sl) 2023-04-28
PT3721888T (pt) 2022-11-02
EP4119153C0 (en) 2024-04-24
US11780931B2 (en) 2023-10-10
US11230607B2 (en) 2022-01-25
ES2649165T3 (es) 2018-01-10
ES2928001T3 (es) 2022-11-14
PL3721888T3 (pl) 2023-04-11
WO2014124028A1 (en) 2014-08-14
US20150376288A1 (en) 2015-12-31
EP3311824A1 (en) 2018-04-25
US10184004B2 (en) 2019-01-22
EP3721888B1 (en) 2022-07-20
EP2953633A4 (en) 2016-09-14
EP2953633B1 (en) 2017-10-04
US20190092873A1 (en) 2019-03-28
ES2983571T3 (es) 2024-10-23
US20170362332A1 (en) 2017-12-21
CA2900256C (en) 2023-03-21
ES2794700T3 (es) 2020-11-18
CA2900256A1 (en) 2014-08-14
EP2953633A1 (en) 2015-12-16

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