PL3917423T3 - Dostarczanie pól leczących guzy (pól elektrycznych do leczenia nowotworów ttfields) za pomocą wszczepialnych szyków przetworników - Google Patents
Dostarczanie pól leczących guzy (pól elektrycznych do leczenia nowotworów ttfields) za pomocą wszczepialnych szyków przetwornikówInfo
- Publication number
- PL3917423T3 PL3917423T3 PL20710293.0T PL20710293T PL3917423T3 PL 3917423 T3 PL3917423 T3 PL 3917423T3 PL 20710293 T PL20710293 T PL 20710293T PL 3917423 T3 PL3917423 T3 PL 3917423T3
- Authority
- PL
- Poland
- Prior art keywords
- ttfields
- transducer arrays
- implantable transducer
- tumor treating
- treating fields
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 238000003491 array Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36002—Cancer treatment, e.g. tumour
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/378—Electrical supply
- A61N1/3787—Electrical supply from an external energy source
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/1206—Generators therefor
- A61B18/1233—Generators therefor with circuits for assuring patient safety
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/0016—Energy applicators arranged in a two- or three dimensional array
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00321—Head or parts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00642—Sensing and controlling the application of energy with feedback, i.e. closed loop control
- A61B2018/00654—Sensing and controlling the application of energy with feedback, i.e. closed loop control with individual control of each of a plurality of energy emitting elements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00696—Controlled or regulated parameters
- A61B2018/00702—Power or energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00696—Controlled or regulated parameters
- A61B2018/00714—Temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00791—Temperature
- A61B2018/00797—Temperature measured by multiple temperature sensors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00791—Temperature
- A61B2018/00815—Temperature measured by a thermistor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/1206—Generators therefor
- A61B2018/1226—Generators therefor powered by a battery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B2018/1467—Probes or electrodes therefor using more than two electrodes on a single probe
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B2018/147—Electrodes transferring energy by capacitive coupling, i.e. with a dielectricum between electrode and target tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Radiology & Medical Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Surgery (AREA)
- Cardiology (AREA)
- Plasma & Fusion (AREA)
- Otolaryngology (AREA)
- Physics & Mathematics (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Electrotherapy Devices (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962811311P | 2019-02-27 | 2019-02-27 | |
| PCT/IB2020/051660 WO2020174429A1 (en) | 2019-02-27 | 2020-02-26 | Delivering tumor treating fields (ttfields) using implantable transducer arrays |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3917423T3 true PL3917423T3 (pl) | 2025-03-31 |
Family
ID=69780254
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL20710293.0T PL3917423T3 (pl) | 2019-02-27 | 2020-02-26 | Dostarczanie pól leczących guzy (pól elektrycznych do leczenia nowotworów ttfields) za pomocą wszczepialnych szyków przetworników |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US11471676B2 (pl) |
| EP (3) | EP4491214A3 (pl) |
| JP (3) | JP2022522936A (pl) |
| CN (1) | CN113453638A (pl) |
| ES (1) | ES3002779T3 (pl) |
| HU (1) | HUE069341T2 (pl) |
| PL (1) | PL3917423T3 (pl) |
| WO (1) | WO2020174429A1 (pl) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10779875B2 (en) | 2013-05-06 | 2020-09-22 | Novocure Gmbh | Optimizing treatment using TTfields by changing the frequency during the course of long term tumor treatment |
| US10188851B2 (en) | 2015-10-28 | 2019-01-29 | Novocure Limited | TTField treatment with optimization of electrode positions on the head based on MRI-based conductivity measurements |
| US10821283B2 (en) | 2016-04-04 | 2020-11-03 | Novocure Gmbh | Reducing motility of cancer cells using tumor treating fields (TTFields) |
| CN110178029B (zh) | 2017-01-19 | 2021-11-16 | 诺沃库勒有限责任公司 | 用于在施加TTFields的同时在显微镜下观察细胞培养物的系统 |
| US11986647B2 (en) | 2018-09-07 | 2024-05-21 | Novocure Gmbh | Treating autoinflammatory and mitochondrial diseases using an alternating electric field |
| JP7148722B2 (ja) | 2018-10-25 | 2022-10-05 | ゼーヴ・ボンゾン | 被験者の脊椎構造体に対する交番電界(例えばTTField)の送達 |
| EP4019080B1 (en) | 2018-11-19 | 2025-06-25 | Novocure GmbH | Arrays for delivering tumor treating fields (ttfields) with selectively addressable sub-elements |
| CN118079235A (zh) | 2018-11-29 | 2024-05-28 | 诺沃库勒有限责任公司 | 用于递送TTField(肿瘤治疗场)的增强灵活性换能器阵列 |
| US11276171B2 (en) | 2019-01-08 | 2022-03-15 | Novocure Gmbh | Evaluating quality of segmentation of an image into different types of tissue for planning treatment using tumor treating fields (TTFields) |
| PL3917423T3 (pl) | 2019-02-27 | 2025-03-31 | Novocure Gmbh | Dostarczanie pól leczących guzy (pól elektrycznych do leczenia nowotworów ttfields) za pomocą wszczepialnych szyków przetworników |
| WO2021019403A1 (en) | 2019-07-31 | 2021-02-04 | Yoram Wasserman | Applying tumor treating fields (ttfields) via electrodes embedded into skull implants |
| US12343336B2 (en) | 2019-08-05 | 2025-07-01 | Novocure Gmbh | Increasing cancer cells' sensitivity to tumor treating fields (TTFields) by inhibiting IL11 activity |
| US11890467B2 (en) | 2019-08-30 | 2024-02-06 | Novocure Gmbh | Delivering tumor treating fields (TTFields) to the neck |
| US12121739B2 (en) | 2019-12-31 | 2024-10-22 | Novocure Gmbh | Methods, systems, and apparatuses for managing temperatures induced by alternating fields |
| PL4074367T3 (pl) | 2019-12-31 | 2023-07-31 | Novocure Gmbh | Szyki do dostarczania zmiennych pól elektrycznych do leczenia nowotworów (ttfields) z indywidualnie dostępnymi elementami elektrody i czujnikami temperatury |
| MX2022006135A (es) | 2019-12-31 | 2022-06-17 | Novocure Gmbh | Generador de ondas sinusoidales de alta eficiencia, alto voltaje, que evita los picos durante los ajustes de amplitud y la conmutacion de canales. |
| US20210299440A1 (en) | 2020-03-30 | 2021-09-30 | Novocure Gmbh | Intravenous / Intra-Spinal / Intra-Cavity / Intraventricular Delivery of TTFields (Tumor Treating Fields) for Treating Cancer and Metastases |
| IL295251A (en) | 2020-04-24 | 2022-10-01 | Novocure Gmbh | Using alternating electric fields to increase permeability of the blood brain barrier |
| US11818943B2 (en) | 2020-06-25 | 2023-11-14 | Novocure Gmbh | Fabricating organic light emitting diodes (OLEDs) using tubulin |
| EP4656236A1 (en) * | 2020-09-30 | 2025-12-03 | Novocure GmbH | Implantable arrays for providing tumor treating fields |
| EP4570303A3 (en) * | 2020-12-21 | 2025-07-30 | Novocure GmbH | Optimization of composite electrode |
| CN113368389B (zh) * | 2021-06-08 | 2023-03-14 | 湖南安泰康成生物科技有限公司 | 利用电场抑制肿瘤增殖的设备及其控制方法和装置 |
| MX2023014225A (es) * | 2021-06-30 | 2024-01-24 | Novocure Gmbh | Uso de condensadores para regular la corriente en matrices de transductores para aplicar campos de tratamiento de tumores (ttfields). |
| CN113694370B (zh) * | 2021-08-25 | 2024-06-14 | 杭州维纳安可医疗科技有限责任公司 | 植入式目标电场递送装置 |
| EP4376939A1 (en) * | 2021-09-14 | 2024-06-05 | Novocure GmbH | Temperature independent method and system for applying ttfields |
| CN113926079A (zh) * | 2021-10-15 | 2022-01-14 | 杭州维纳安可医疗科技有限责任公司 | 植入式电极片及其控制系统 |
| US12377280B2 (en) * | 2021-12-30 | 2025-08-05 | Novocure Gmbh | Selecting values of parameters for treatment using tumor treating fields (TTFields) |
| IL314392A (en) | 2022-03-30 | 2024-09-01 | Novocure Gmbh | Reducing electrosensation whilst treating a subject using alternating electric fields by pairing transducer arrays together |
| JP2025511071A (ja) | 2022-03-30 | 2025-04-15 | ノボキュア ゲーエムベーハー | インターリーブ冷却期間による腫瘍治療場のピーク強度強化 |
| CN116271523B (zh) * | 2022-12-30 | 2024-03-29 | 江苏海莱新创医疗科技有限公司 | 电极片、电极片识别方法、肿瘤电场治疗系统及治疗设备 |
| US20240157130A1 (en) * | 2022-11-10 | 2024-05-16 | Mayo Foundation For Medical Education And Research | Implantable medical systems for cancer treatment with thermal management features |
| US20240189580A1 (en) * | 2022-12-07 | 2024-06-13 | Mayo Foundation For Medical Education And Research | Stimulation leads and systems for cancer treatment with low resistance and heat generation |
| KR20250143309A (ko) * | 2023-02-06 | 2025-10-01 | 노보큐어 게엠베하 | 이방성 재료 층을 갖는 이동 가능한 트랜스듀서 어레이 |
| US12268863B2 (en) | 2023-02-06 | 2025-04-08 | Novocure Gmbh | Shiftable transducer array with anisotropic material layer |
| CN115970155B (zh) * | 2023-03-22 | 2023-08-22 | 深圳奥派森生物电磁科技有限公司 | 金属基板电极、肿瘤电场治疗电极及系统 |
| ES2967801A1 (es) * | 2023-12-22 | 2024-05-03 | Univ Madrid Politecnica | Dispositivo de implante para tratamiento de patologías mediante campos eléctricos |
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| US10188851B2 (en) | 2015-10-28 | 2019-01-29 | Novocure Limited | TTField treatment with optimization of electrode positions on the head based on MRI-based conductivity measurements |
| US10821283B2 (en) * | 2016-04-04 | 2020-11-03 | Novocure Gmbh | Reducing motility of cancer cells using tumor treating fields (TTFields) |
| AU2017289870B2 (en) | 2016-06-30 | 2021-12-23 | Novocure Gmbh | Arrays for longitudinal delivery of TTFields to a body |
| CA2972699A1 (en) | 2016-07-10 | 2018-01-10 | Novocure Limited | Synchronizing tumor cells to the g2/m phase using ttfields combined with taxane or other anti-microtubule agents |
| US11097101B2 (en) * | 2016-08-18 | 2021-08-24 | Novocure Gmbh | Temperature measurement in arrays for delivering TTFields |
| PL3554631T3 (pl) | 2016-12-13 | 2022-09-12 | Novocure Gmbh | Leczenie pacjentów polami ttfields ze zoptymalizowanymi pozycjami elektrod z wykorzystaniem odkształcalnych matryc |
| CN110178029B (zh) | 2017-01-19 | 2021-11-16 | 诺沃库勒有限责任公司 | 用于在施加TTFields的同时在显微镜下观察细胞培养物的系统 |
| CN207445341U (zh) * | 2017-04-25 | 2018-06-05 | 孙建国 | 导药电极装置 |
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| US11338135B2 (en) | 2017-10-23 | 2022-05-24 | Cardiac Pacemakers, Inc. | Medical devices for cancer therapy with electric field shaping elements |
| US20190117973A1 (en) | 2017-10-23 | 2019-04-25 | Cardiac Pacemakers, Inc. | Electric field cancer therapy devices with feedback mechanisms and diagnostics |
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| US20190117971A1 (en) | 2017-10-23 | 2019-04-25 | Cardiac Pacemakers, Inc. | Volume-filling leads for treatment of cancer with electric fields |
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-
2020
- 2020-02-26 PL PL20710293.0T patent/PL3917423T3/pl unknown
- 2020-02-26 WO PCT/IB2020/051660 patent/WO2020174429A1/en not_active Ceased
- 2020-02-26 HU HUE20710293A patent/HUE069341T2/hu unknown
- 2020-02-26 EP EP24216527.2A patent/EP4491214A3/en active Pending
- 2020-02-26 EP EP20710293.0A patent/EP3917423B1/en active Active
- 2020-02-26 ES ES20710293T patent/ES3002779T3/es active Active
- 2020-02-26 US US16/801,972 patent/US11471676B2/en active Active
- 2020-02-26 CN CN202080017346.6A patent/CN113453638A/zh active Pending
- 2020-02-26 EP EP21188422.6A patent/EP3954314B1/en active Active
- 2020-02-26 JP JP2021539032A patent/JP2022522936A/ja active Pending
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2022
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2023
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- 2023-09-15 US US18/368,876 patent/US12285605B2/en active Active
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2025
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Also Published As
| Publication number | Publication date |
|---|---|
| JP2022522936A (ja) | 2022-04-21 |
| WO2020174429A1 (en) | 2020-09-03 |
| EP4491214A2 (en) | 2025-01-15 |
| EP3954314A1 (en) | 2022-02-16 |
| US11471676B2 (en) | 2022-10-18 |
| US20230001197A1 (en) | 2023-01-05 |
| US20230191123A1 (en) | 2023-06-22 |
| US11857782B2 (en) | 2024-01-02 |
| US11607543B2 (en) | 2023-03-21 |
| US20200269043A1 (en) | 2020-08-27 |
| US12285605B2 (en) | 2025-04-29 |
| EP3917423A1 (en) | 2021-12-08 |
| US20240001115A1 (en) | 2024-01-04 |
| EP3954314C0 (en) | 2025-01-08 |
| ES3002779T3 (en) | 2025-03-07 |
| JP2025133744A (ja) | 2025-09-11 |
| EP3954314B1 (en) | 2025-01-08 |
| EP4491214A3 (en) | 2025-03-12 |
| CN113453638A (zh) | 2021-09-28 |
| EP3917423B1 (en) | 2024-11-13 |
| JP2023133309A (ja) | 2023-09-22 |
| HUE069341T2 (hu) | 2025-03-28 |
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