PL3917423T3 - Dostarczanie pól leczących guzy (pól elektrycznych do leczenia nowotworów ttfields) za pomocą wszczepialnych szyków przetworników - Google Patents

Dostarczanie pól leczących guzy (pól elektrycznych do leczenia nowotworów ttfields) za pomocą wszczepialnych szyków przetworników

Info

Publication number
PL3917423T3
PL3917423T3 PL20710293.0T PL20710293T PL3917423T3 PL 3917423 T3 PL3917423 T3 PL 3917423T3 PL 20710293 T PL20710293 T PL 20710293T PL 3917423 T3 PL3917423 T3 PL 3917423T3
Authority
PL
Poland
Prior art keywords
ttfields
transducer arrays
implantable transducer
tumor treating
treating fields
Prior art date
Application number
PL20710293.0T
Other languages
English (en)
Inventor
Zeev Bomzon
Hadas Sara Hershkovich
Ariel NAVEH
Moshe Giladi
Eilon KIRSON
Golan BAR-TAL
Tali Voloshin-Sela
Yoram Wasserman
Original Assignee
Novocure Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novocure Gmbh filed Critical Novocure Gmbh
Publication of PL3917423T3 publication Critical patent/PL3917423T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36002Cancer treatment, e.g. tumour
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372Arrangements in connection with the implantation of stimulators
    • A61N1/378Electrical supply
    • A61N1/3787Electrical supply from an external energy source
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/1206Generators therefor
    • A61B18/1233Generators therefor with circuits for assuring patient safety
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053Mechanical features of the instrument of device
    • A61B2018/0016Energy applicators arranged in a two- or three dimensional array
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00321Head or parts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00642Sensing and controlling the application of energy with feedback, i.e. closed loop control
    • A61B2018/00654Sensing and controlling the application of energy with feedback, i.e. closed loop control with individual control of each of a plurality of energy emitting elements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00696Controlled or regulated parameters
    • A61B2018/00702Power or energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00696Controlled or regulated parameters
    • A61B2018/00714Temperature
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00773Sensed parameters
    • A61B2018/00791Temperature
    • A61B2018/00797Temperature measured by multiple temperature sensors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00773Sensed parameters
    • A61B2018/00791Temperature
    • A61B2018/00815Temperature measured by a thermistor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/1206Generators therefor
    • A61B2018/1226Generators therefor powered by a battery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B2018/1467Probes or electrodes therefor using more than two electrodes on a single probe
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B2018/147Electrodes transferring energy by capacitive coupling, i.e. with a dielectricum between electrode and target tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/40Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Surgery (AREA)
  • Cardiology (AREA)
  • Plasma & Fusion (AREA)
  • Otolaryngology (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Electrotherapy Devices (AREA)
PL20710293.0T 2019-02-27 2020-02-26 Dostarczanie pól leczących guzy (pól elektrycznych do leczenia nowotworów ttfields) za pomocą wszczepialnych szyków przetworników PL3917423T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962811311P 2019-02-27 2019-02-27
PCT/IB2020/051660 WO2020174429A1 (en) 2019-02-27 2020-02-26 Delivering tumor treating fields (ttfields) using implantable transducer arrays

Publications (1)

Publication Number Publication Date
PL3917423T3 true PL3917423T3 (pl) 2025-03-31

Family

ID=69780254

Family Applications (1)

Application Number Title Priority Date Filing Date
PL20710293.0T PL3917423T3 (pl) 2019-02-27 2020-02-26 Dostarczanie pól leczących guzy (pól elektrycznych do leczenia nowotworów ttfields) za pomocą wszczepialnych szyków przetworników

Country Status (8)

Country Link
US (4) US11471676B2 (pl)
EP (3) EP4491214A3 (pl)
JP (3) JP2022522936A (pl)
CN (1) CN113453638A (pl)
ES (1) ES3002779T3 (pl)
HU (1) HUE069341T2 (pl)
PL (1) PL3917423T3 (pl)
WO (1) WO2020174429A1 (pl)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10779875B2 (en) 2013-05-06 2020-09-22 Novocure Gmbh Optimizing treatment using TTfields by changing the frequency during the course of long term tumor treatment
US10188851B2 (en) 2015-10-28 2019-01-29 Novocure Limited TTField treatment with optimization of electrode positions on the head based on MRI-based conductivity measurements
US10821283B2 (en) 2016-04-04 2020-11-03 Novocure Gmbh Reducing motility of cancer cells using tumor treating fields (TTFields)
CN110178029B (zh) 2017-01-19 2021-11-16 诺沃库勒有限责任公司 用于在施加TTFields的同时在显微镜下观察细胞培养物的系统
US11986647B2 (en) 2018-09-07 2024-05-21 Novocure Gmbh Treating autoinflammatory and mitochondrial diseases using an alternating electric field
JP7148722B2 (ja) 2018-10-25 2022-10-05 ゼーヴ・ボンゾン 被験者の脊椎構造体に対する交番電界(例えばTTField)の送達
EP4019080B1 (en) 2018-11-19 2025-06-25 Novocure GmbH Arrays for delivering tumor treating fields (ttfields) with selectively addressable sub-elements
CN118079235A (zh) 2018-11-29 2024-05-28 诺沃库勒有限责任公司 用于递送TTField(肿瘤治疗场)的增强灵活性换能器阵列
US11276171B2 (en) 2019-01-08 2022-03-15 Novocure Gmbh Evaluating quality of segmentation of an image into different types of tissue for planning treatment using tumor treating fields (TTFields)
PL3917423T3 (pl) 2019-02-27 2025-03-31 Novocure Gmbh Dostarczanie pól leczących guzy (pól elektrycznych do leczenia nowotworów ttfields) za pomocą wszczepialnych szyków przetworników
WO2021019403A1 (en) 2019-07-31 2021-02-04 Yoram Wasserman Applying tumor treating fields (ttfields) via electrodes embedded into skull implants
US12343336B2 (en) 2019-08-05 2025-07-01 Novocure Gmbh Increasing cancer cells' sensitivity to tumor treating fields (TTFields) by inhibiting IL11 activity
US11890467B2 (en) 2019-08-30 2024-02-06 Novocure Gmbh Delivering tumor treating fields (TTFields) to the neck
US12121739B2 (en) 2019-12-31 2024-10-22 Novocure Gmbh Methods, systems, and apparatuses for managing temperatures induced by alternating fields
PL4074367T3 (pl) 2019-12-31 2023-07-31 Novocure Gmbh Szyki do dostarczania zmiennych pól elektrycznych do leczenia nowotworów (ttfields) z indywidualnie dostępnymi elementami elektrody i czujnikami temperatury
MX2022006135A (es) 2019-12-31 2022-06-17 Novocure Gmbh Generador de ondas sinusoidales de alta eficiencia, alto voltaje, que evita los picos durante los ajustes de amplitud y la conmutacion de canales.
US20210299440A1 (en) 2020-03-30 2021-09-30 Novocure Gmbh Intravenous / Intra-Spinal / Intra-Cavity / Intraventricular Delivery of TTFields (Tumor Treating Fields) for Treating Cancer and Metastases
IL295251A (en) 2020-04-24 2022-10-01 Novocure Gmbh Using alternating electric fields to increase permeability of the blood brain barrier
US11818943B2 (en) 2020-06-25 2023-11-14 Novocure Gmbh Fabricating organic light emitting diodes (OLEDs) using tubulin
EP4656236A1 (en) * 2020-09-30 2025-12-03 Novocure GmbH Implantable arrays for providing tumor treating fields
EP4570303A3 (en) * 2020-12-21 2025-07-30 Novocure GmbH Optimization of composite electrode
CN113368389B (zh) * 2021-06-08 2023-03-14 湖南安泰康成生物科技有限公司 利用电场抑制肿瘤增殖的设备及其控制方法和装置
MX2023014225A (es) * 2021-06-30 2024-01-24 Novocure Gmbh Uso de condensadores para regular la corriente en matrices de transductores para aplicar campos de tratamiento de tumores (ttfields).
CN113694370B (zh) * 2021-08-25 2024-06-14 杭州维纳安可医疗科技有限责任公司 植入式目标电场递送装置
EP4376939A1 (en) * 2021-09-14 2024-06-05 Novocure GmbH Temperature independent method and system for applying ttfields
CN113926079A (zh) * 2021-10-15 2022-01-14 杭州维纳安可医疗科技有限责任公司 植入式电极片及其控制系统
US12377280B2 (en) * 2021-12-30 2025-08-05 Novocure Gmbh Selecting values of parameters for treatment using tumor treating fields (TTFields)
IL314392A (en) 2022-03-30 2024-09-01 Novocure Gmbh Reducing electrosensation whilst treating a subject using alternating electric fields by pairing transducer arrays together
JP2025511071A (ja) 2022-03-30 2025-04-15 ノボキュア ゲーエムベーハー インターリーブ冷却期間による腫瘍治療場のピーク強度強化
CN116271523B (zh) * 2022-12-30 2024-03-29 江苏海莱新创医疗科技有限公司 电极片、电极片识别方法、肿瘤电场治疗系统及治疗设备
US20240157130A1 (en) * 2022-11-10 2024-05-16 Mayo Foundation For Medical Education And Research Implantable medical systems for cancer treatment with thermal management features
US20240189580A1 (en) * 2022-12-07 2024-06-13 Mayo Foundation For Medical Education And Research Stimulation leads and systems for cancer treatment with low resistance and heat generation
KR20250143309A (ko) * 2023-02-06 2025-10-01 노보큐어 게엠베하 이방성 재료 층을 갖는 이동 가능한 트랜스듀서 어레이
US12268863B2 (en) 2023-02-06 2025-04-08 Novocure Gmbh Shiftable transducer array with anisotropic material layer
CN115970155B (zh) * 2023-03-22 2023-08-22 深圳奥派森生物电磁科技有限公司 金属基板电极、肿瘤电场治疗电极及系统
ES2967801A1 (es) * 2023-12-22 2024-05-03 Univ Madrid Politecnica Dispositivo de implante para tratamiento de patologías mediante campos eléctricos

Family Cites Families (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0132276B1 (en) * 1983-01-21 1991-08-14 Ramm Associates Implantable hyperthermia device and system
US6575969B1 (en) * 1995-05-04 2003-06-10 Sherwood Services Ag Cool-tip radiofrequency thermosurgery electrode system for tumor ablation
US6558378B2 (en) * 1998-05-05 2003-05-06 Cardiac Pacemakers, Inc. RF ablation system and method having automatic temperature control
US20080033492A1 (en) * 2000-01-07 2008-02-07 Biowave Corporation Electro-therapy method
US7136699B2 (en) 2002-10-02 2006-11-14 Standen, Ltd. Apparatus for destroying dividing cells
US7089054B2 (en) 2002-10-02 2006-08-08 Standen Ltd. Apparatus and method for treating a tumor or the like
US8175698B2 (en) 2000-02-17 2012-05-08 Novocure Ltd. Treating bacteria with electric fields
US7016725B2 (en) 2001-11-06 2006-03-21 Standen Ltd. Method and apparatus for destroying dividing cells
US7565206B2 (en) 2000-02-17 2009-07-21 Standen Ltd. Treating a tumor or the like with electric fields at different orientations
US6868289B2 (en) 2002-10-02 2005-03-15 Standen Ltd. Apparatus for treating a tumor or the like and articles incorporating the apparatus for treatment of the tumor
CN1416466A (zh) 2000-02-17 2003-05-07 约朗姆·帕尔蒂 破坏正在分裂的细胞的方法和装置
US8447395B2 (en) 2000-02-17 2013-05-21 Novocure Ltd Treating bacteria with electric fields
US7599746B2 (en) 2000-02-17 2009-10-06 Standen Ltd Apparatus and method for preventing the spread of cancerous metastases and for elimination of metastases
BE1013664A3 (nl) * 2000-08-30 2002-06-04 Declercq Henri Zenuwstimulatieapparaat.
EP1706178B1 (en) * 2004-01-22 2013-04-24 Rehabtronics Inc. System for routing electrical current to bodily tissues via implanted passive conductors
US20050222646A1 (en) * 2004-04-06 2005-10-06 Kai Kroll Method and device for treating cancer with modified output electrical therapy
CN1976738B (zh) 2004-04-23 2010-09-01 诺沃库勒有限公司 使用不同频率的电场治疗肿瘤等
DK1833552T3 (da) 2004-12-07 2010-08-02 Standen Ltd Elektroder til anbringelse af et elektrisk felt in-vivo i en længere tidsperiode
PT1933937E (pt) 2005-10-03 2015-04-23 Novocure Ltd Optimização de características de um campo eléctrico para aumentar o efeito do campo em células proliferantes
US8019414B2 (en) 2006-04-05 2011-09-13 Novocure Ltd. Treating cancer using electromagnetic fields in combination with other treatment regimens
US8465533B2 (en) 2007-03-06 2013-06-18 Novocure Limited Treating cancer using electromagnetic fields in combination with photodynamic therapy
PT2183024T (pt) 2007-08-14 2019-08-01 Novocure Ltd Tratando parasitas com campos elétricos
US8715203B2 (en) 2007-09-17 2014-05-06 Novocure Limited Composite electrode
US20170049513A1 (en) * 2009-11-06 2017-02-23 Cosman Medical, Inc. Multiple electrode generator
US9155589B2 (en) * 2010-07-30 2015-10-13 Boston Scientific Scimed, Inc. Sequential activation RF electrode set for renal nerve ablation
US10842563B2 (en) * 2013-03-15 2020-11-24 Covidien Lp System and method for power control of electrosurgical resonant inverters
US10779875B2 (en) 2013-05-06 2020-09-22 Novocure Gmbh Optimizing treatment using TTfields by changing the frequency during the course of long term tumor treatment
US9655669B2 (en) 2013-05-06 2017-05-23 Novocure Limited Optimizing treatment using TTFields by changing the frequency during the course of long term tumor treatment
US20190117963A1 (en) 2014-07-25 2019-04-25 Loyalty Based Innovations, LLC Apparatus and method for treating multiple tumors in patients with metastatic disease by electric fields
US9833617B2 (en) 2014-07-25 2017-12-05 Loyalty Based Innovations, LLC Apparatus and method for treating multiple tumors in patients with metastatic disease by electric fields
US20160166326A1 (en) * 2014-11-25 2016-06-16 Medtronic Bakken Research Center B.V. Medical lead bending sensor
US9910453B2 (en) 2015-09-25 2018-03-06 Novocure Limited High voltage, high efficiency sine wave generator with pre-set frequency and adjustable amplitude
US10155107B2 (en) * 2015-10-07 2018-12-18 Medtronic, Inc. Implantable modular electrode array assembly
US10188851B2 (en) 2015-10-28 2019-01-29 Novocure Limited TTField treatment with optimization of electrode positions on the head based on MRI-based conductivity measurements
US10821283B2 (en) * 2016-04-04 2020-11-03 Novocure Gmbh Reducing motility of cancer cells using tumor treating fields (TTFields)
AU2017289870B2 (en) 2016-06-30 2021-12-23 Novocure Gmbh Arrays for longitudinal delivery of TTFields to a body
CA2972699A1 (en) 2016-07-10 2018-01-10 Novocure Limited Synchronizing tumor cells to the g2/m phase using ttfields combined with taxane or other anti-microtubule agents
US11097101B2 (en) * 2016-08-18 2021-08-24 Novocure Gmbh Temperature measurement in arrays for delivering TTFields
PL3554631T3 (pl) 2016-12-13 2022-09-12 Novocure Gmbh Leczenie pacjentów polami ttfields ze zoptymalizowanymi pozycjami elektrod z wykorzystaniem odkształcalnych matryc
CN110178029B (zh) 2017-01-19 2021-11-16 诺沃库勒有限责任公司 用于在施加TTFields的同时在显微镜下观察细胞培养物的系统
CN207445341U (zh) * 2017-04-25 2018-06-05 孙建国 导药电极装置
US12403306B2 (en) 2017-10-23 2025-09-02 Cardiac Pacemakers, Inc. Electric field shaping leads for treatment of cancer
US11338135B2 (en) 2017-10-23 2022-05-24 Cardiac Pacemakers, Inc. Medical devices for cancer therapy with electric field shaping elements
US20190117973A1 (en) 2017-10-23 2019-04-25 Cardiac Pacemakers, Inc. Electric field cancer therapy devices with feedback mechanisms and diagnostics
US20190117969A1 (en) 2017-10-23 2019-04-25 Cardiac Pacemakers, Inc. Medical devices for treatment of cancer with electric fields
US20190117971A1 (en) 2017-10-23 2019-04-25 Cardiac Pacemakers, Inc. Volume-filling leads for treatment of cancer with electric fields
EP3773726B1 (en) 2018-04-09 2024-06-05 Novocure GmbH Treating tumors with ttfields and an aurora kinase inhibitor
KR102687814B1 (ko) 2018-04-10 2024-07-24 지브 봄존 서로 다른 반복 시간을 가지는 두 개의 MRI 이미지들로부터 얻어진 1MHz 미만 저주파 교류 전도도 추산치
DK3838333T3 (da) 2018-07-03 2023-03-27 Univ Leland Stanford Junior Anvendelse af elektriske vekselfelter til forøgelse af cellmembranpermeabilitet
US11179322B2 (en) 2018-07-10 2021-11-23 Novocure Gmbh Methods and compositions for treating tumors with TTFields and sorafenib
MX2020013431A (es) 2018-07-18 2021-05-27 Novocure Gmbh Uso de densidad de perdida de potencia y mediciones relacionadas para cuantificar la dosis de campos de tratamiento de tumores (ttfield).
CN112618956B (zh) 2018-08-23 2025-06-27 诺沃库勒有限责任公司 使用交变电场来提高血脑屏障的通透性
US11160977B2 (en) 2018-09-04 2021-11-02 Novocure Gmbh Delivering tumor treating fields (TTFields) to the infratentorial brain
CN112770806B (zh) 2018-09-07 2025-12-05 诺沃库勒有限责任公司 使用交变电场治疗自身免疫性疾病以减少t细胞的增殖
US20200108031A1 (en) 2018-10-05 2020-04-09 Novocure Gmbh Treating Tumors Using TTFields Combined with ABT-751
JP7282411B2 (ja) 2018-10-23 2023-05-29 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 交流電場を使用する、幹細胞に基づく療法におけるテラトーマ形成の予防及び処置
JP7148722B2 (ja) 2018-10-25 2022-10-05 ゼーヴ・ボンゾン 被験者の脊椎構造体に対する交番電界(例えばTTField)の送達
US20200146586A1 (en) 2018-11-14 2020-05-14 Novocure Gmbh Creating Accurate Computational Head Models of Patients Using Datasets Combining MRI and CT Images
EP4019080B1 (en) 2018-11-19 2025-06-25 Novocure GmbH Arrays for delivering tumor treating fields (ttfields) with selectively addressable sub-elements
CN118079235A (zh) 2018-11-29 2024-05-28 诺沃库勒有限责任公司 用于递送TTField(肿瘤治疗场)的增强灵活性换能器阵列
US11276171B2 (en) 2019-01-08 2022-03-15 Novocure Gmbh Evaluating quality of segmentation of an image into different types of tissue for planning treatment using tumor treating fields (TTFields)
PL3917423T3 (pl) * 2019-02-27 2025-03-31 Novocure Gmbh Dostarczanie pól leczących guzy (pól elektrycznych do leczenia nowotworów ttfields) za pomocą wszczepialnych szyków przetworników
JP7410176B2 (ja) 2019-04-22 2024-01-09 ボストン サイエンティフィック サイムド,インコーポレイテッド 癌を治療するために電気刺激を与えるためのシステム
CN113727753B (zh) 2019-04-22 2024-09-13 波士顿科学国际有限公司 用于癌症治疗的电刺激装置
EP4480526A3 (en) 2019-04-22 2025-03-12 Boston Scientific Scimed, Inc. Combination electrical and chemotherapeutic treatment of cancer
CN113747936B (zh) 2019-04-23 2024-06-18 波士顿科学国际有限公司 用于电刺激来治疗癌症的电极
CN113766950A (zh) 2019-04-23 2021-12-07 波士顿科学国际有限公司 带有热治疗或热监测的电刺激
WO2020219517A2 (en) 2019-04-23 2020-10-29 Boston Scientific Scimed, Inc. Electrical stimulation for cancer treatment with internal and external electrodes

Also Published As

Publication number Publication date
JP2022522936A (ja) 2022-04-21
WO2020174429A1 (en) 2020-09-03
EP4491214A2 (en) 2025-01-15
EP3954314A1 (en) 2022-02-16
US11471676B2 (en) 2022-10-18
US20230001197A1 (en) 2023-01-05
US20230191123A1 (en) 2023-06-22
US11857782B2 (en) 2024-01-02
US11607543B2 (en) 2023-03-21
US20200269043A1 (en) 2020-08-27
US12285605B2 (en) 2025-04-29
EP3917423A1 (en) 2021-12-08
US20240001115A1 (en) 2024-01-04
EP3954314C0 (en) 2025-01-08
ES3002779T3 (en) 2025-03-07
JP2025133744A (ja) 2025-09-11
EP3954314B1 (en) 2025-01-08
EP4491214A3 (en) 2025-03-12
CN113453638A (zh) 2021-09-28
EP3917423B1 (en) 2024-11-13
JP2023133309A (ja) 2023-09-22
HUE069341T2 (hu) 2025-03-28

Similar Documents

Publication Publication Date Title
PL3917423T3 (pl) Dostarczanie pól leczących guzy (pól elektrycznych do leczenia nowotworów ttfields) za pomocą wszczepialnych szyków przetworników
IL280844A (en) Transducer arrays with improved flexibility to provide tumor treating fields
IL280843A (en) Arrays for administration of fields treat the tumor with sub-elements administered selectively
EP4061477C0 (en) IMPLANTABLE NETWORKS TO PROVIDE TUMOR TREATMENT FIELDS
IL278922A (en) Decentralized pacing system
PL3897817T3 (pl) System do stymulacyjnej terapii mikroprądowej
EP4185375C0 (en) IMPLANTABLE NETWORKS TO PROVIDE TUMOR TREATMENT FIELDS
GB201913902D0 (en) Nerve Stimulation
ZA202206743B (en) Therapy for the treatment of cancer
ZA202206167B (en) Magnetic nerve stimulator
SG11202107229PA (en) Intravenous therapy selection system
GB202003618D0 (en) Gene Therapy
GB201905780D0 (en) Cancer therapy
GB202114972D0 (en) Gene therapy
ZA202100244B (en) Combinatorial gene therapy
IL292502A (en) Therapeutic methods using vadadustat
GB2583140B (en) Radiation therapy system
IL287135A (en) Cancer treatment methods
HUE067478T2 (hu) Terápiás készülék sejt terápiához vagy sejt stimulációhoz
SG11202110844UA (en) Mixed-cell gene therapy
GB202010894D0 (en) Gene therapy
GB202003109D0 (en) Gene therapy
GB202002202D0 (en) Gene therapy
HK40076746A (en) Implantable arrays for providing tumor treating fields
IL286198A (en) Cancer treatment methods