PL3880675T3 - Związki antybiotykowe, sposoby ich wytwarzania, kompozycje farmaceutyczne zawierające te związki oraz ich zastosowanie - Google Patents
Związki antybiotykowe, sposoby ich wytwarzania, kompozycje farmaceutyczne zawierające te związki oraz ich zastosowanieInfo
- Publication number
- PL3880675T3 PL3880675T3 PL19805569.1T PL19805569T PL3880675T3 PL 3880675 T3 PL3880675 T3 PL 3880675T3 PL 19805569 T PL19805569 T PL 19805569T PL 3880675 T3 PL3880675 T3 PL 3880675T3
- Authority
- PL
- Poland
- Prior art keywords
- compounds
- manufacturing
- methods
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/499—Spiro-condensed pyrazines or piperazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/20—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18205619 | 2018-11-12 | ||
| EP18213016 | 2018-12-17 | ||
| PCT/EP2019/080903 WO2020099341A1 (en) | 2018-11-12 | 2019-11-11 | Antibiotic compounds, methods of manufacturing the same, pharmaceutical compositions containing the same and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3880675T3 true PL3880675T3 (pl) | 2025-02-10 |
Family
ID=68610175
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL19805569.1T PL3880675T3 (pl) | 2018-11-12 | 2019-11-11 | Związki antybiotykowe, sposoby ich wytwarzania, kompozycje farmaceutyczne zawierające te związki oraz ich zastosowanie |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US20230035837A1 (pl) |
| EP (1) | EP3880675B1 (pl) |
| JP (1) | JP2022506957A (pl) |
| KR (1) | KR102872166B1 (pl) |
| CN (1) | CN113272302B (pl) |
| AU (1) | AU2019380568B2 (pl) |
| BR (1) | BR112021009106A2 (pl) |
| CA (1) | CA3119390A1 (pl) |
| CL (2) | CL2021001244A1 (pl) |
| DK (1) | DK3880675T3 (pl) |
| ES (1) | ES3009675T3 (pl) |
| FI (1) | FI3880675T3 (pl) |
| HU (1) | HUE069513T2 (pl) |
| IL (2) | IL311894A (pl) |
| LT (1) | LT3880675T (pl) |
| MX (2) | MX2021005535A (pl) |
| PH (1) | PH12021551058A1 (pl) |
| PL (1) | PL3880675T3 (pl) |
| RS (1) | RS66257B1 (pl) |
| SG (1) | SG11202104863RA (pl) |
| SI (1) | SI3880675T1 (pl) |
| SM (1) | SMT202400519T1 (pl) |
| TN (1) | TN2021000092A1 (pl) |
| UA (1) | UA129248C2 (pl) |
| WO (1) | WO2020099341A1 (pl) |
| ZA (1) | ZA202103516B (pl) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL293980A (en) | 2019-12-19 | 2022-08-01 | Debiopharm Int Sa | New compounds and their use |
| WO2022187329A1 (en) * | 2021-03-03 | 2022-09-09 | The Board Of Trustees Of The University Of Illinois | Fabi inhibitors for gram-negative pathogens |
| CA3223459A1 (en) | 2021-06-23 | 2022-12-29 | Vincent Gerusz | Novel compounds and their use |
| WO2025073269A1 (zh) * | 2023-10-07 | 2025-04-10 | 广州白云山医药集团股份有限公司白云山制药总厂 | 一种FabI酶抑制剂及其应用 |
| WO2025078209A1 (en) | 2023-10-09 | 2025-04-17 | Debiopharm International S.A. | Antibiotic compounds for treating bacterial infections |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6921763B2 (en) | 1999-09-17 | 2005-07-26 | Abbott Laboratories | Pyrazolopyrimidines as therapeutic agents |
| DE60017180T2 (de) * | 1999-10-08 | 2005-12-08 | Affinium Pharmaceuticals, Inc., Toronto | Fab i inhibitoren |
| CA2444597A1 (en) * | 2001-04-06 | 2002-10-06 | Affinium Pharmaceuticals, Inc. | Fab i inhibitors |
| CA2519429C (en) * | 2003-03-17 | 2013-08-06 | Affinium Pharmaceuticals, Inc. | Pharmaceutical compositions comprising inhibitors of fab i and further antibiotics |
| US8450307B2 (en) * | 2004-06-04 | 2013-05-28 | Affinium Pharmaceuticals, Inc. | Therapeutic agents, and methods of making and using the same |
| CN101415701A (zh) * | 2005-12-05 | 2009-04-22 | Affinium医药公司 | 作为fabi抑制剂的杂环丙烯酰胺化合物和抗菌剂 |
| EP1973902A2 (en) | 2005-12-05 | 2008-10-01 | Affinium Pharmaceuticals, Inc. | 3-heterocyclylacrylamide compounds as fabi inhibitors and antibacterial agents |
| US7601716B2 (en) | 2006-05-01 | 2009-10-13 | Cephalon, Inc. | Pyridopyrazines and derivatives thereof as ALK and c-Met inhibitors |
| WO2008009122A1 (en) | 2006-07-20 | 2008-01-24 | Affinium Pharmaceuticals, Inc. | Acrylamide derivatives as fab i inhibitors |
| EP2125802A4 (en) | 2007-02-16 | 2014-08-20 | Debiopharm Int Sa | SALTS, PRODRUGS AND POLYMORPHES OF FAB I INHIBITORS |
| JO3611B1 (ar) | 2011-08-10 | 2020-08-27 | Janssen Sciences Ireland Uc | سايكلو بنتا (سي (بيرول 4,3 ثاني هيدرو 1 hمستبدله [8,1] نافثيريدينونات مضادة للجراثيم |
| WO2013042035A1 (en) | 2011-09-19 | 2013-03-28 | Vitas Pharma Research Private Limited | Heterocyclic compounds as inhibitors of fatty acid biosynthesis for bacterial infections |
| EP2785715A1 (en) | 2011-12-02 | 2014-10-08 | Aurigene Discovery Technologies Limited | Substituted pyridine derivatives as fabi inhibitors |
| DK2861608T3 (da) * | 2012-06-19 | 2019-06-24 | Debiopharm Int Sa | Prodrug-derivater af (e)-n-methyl-n-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamid |
| JP6250667B2 (ja) * | 2012-08-10 | 2017-12-20 | ヤンセン・サイエンシズ・アイルランド・ユーシー | 新しい抗菌化合物 |
| US9951056B2 (en) | 2013-09-30 | 2018-04-24 | Beijing Innocare Pharma Tech Co., Ltd. | Substituted nicotinamide inhibitors of BTK and their preparation and use in the treatment of cancer, inflammation and autoimmune disease |
-
2019
- 2019-11-11 PL PL19805569.1T patent/PL3880675T3/pl unknown
- 2019-11-11 MX MX2021005535A patent/MX2021005535A/es unknown
- 2019-11-11 US US17/292,600 patent/US20230035837A1/en active Pending
- 2019-11-11 EP EP19805569.1A patent/EP3880675B1/en active Active
- 2019-11-11 SI SI201930867T patent/SI3880675T1/sl unknown
- 2019-11-11 TN TNP/2021/000092A patent/TN2021000092A1/en unknown
- 2019-11-11 JP JP2021525117A patent/JP2022506957A/ja active Pending
- 2019-11-11 DK DK19805569.1T patent/DK3880675T3/da active
- 2019-11-11 RS RS20241349A patent/RS66257B1/sr unknown
- 2019-11-11 CA CA3119390A patent/CA3119390A1/en active Pending
- 2019-11-11 SG SG11202104863RA patent/SG11202104863RA/en unknown
- 2019-11-11 HU HUE19805569A patent/HUE069513T2/hu unknown
- 2019-11-11 BR BR112021009106-8A patent/BR112021009106A2/pt unknown
- 2019-11-11 ES ES19805569T patent/ES3009675T3/es active Active
- 2019-11-11 CN CN201980088149.0A patent/CN113272302B/zh active Active
- 2019-11-11 AU AU2019380568A patent/AU2019380568B2/en active Active
- 2019-11-11 WO PCT/EP2019/080903 patent/WO2020099341A1/en not_active Ceased
- 2019-11-11 FI FIEP19805569.1T patent/FI3880675T3/fi active
- 2019-11-11 IL IL311894A patent/IL311894A/en unknown
- 2019-11-11 LT LTEPPCT/EP2019/080903T patent/LT3880675T/lt unknown
- 2019-11-11 KR KR1020217018050A patent/KR102872166B1/ko active Active
- 2019-11-11 UA UAA202103198A patent/UA129248C2/uk unknown
- 2019-11-11 SM SM20240519T patent/SMT202400519T1/it unknown
-
2021
- 2021-05-05 IL IL282950A patent/IL282950A/en unknown
- 2021-05-07 PH PH12021551058A patent/PH12021551058A1/en unknown
- 2021-05-11 MX MX2024010625A patent/MX2024010625A/es unknown
- 2021-05-12 CL CL2021001244A patent/CL2021001244A1/es unknown
- 2021-05-24 ZA ZA2021/03516A patent/ZA202103516B/en unknown
-
2022
- 2022-12-22 CL CL2022003703A patent/CL2022003703A1/es unknown
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