PL3880675T3 - Związki antybiotykowe, sposoby ich wytwarzania, kompozycje farmaceutyczne zawierające te związki oraz ich zastosowanie - Google Patents
Związki antybiotykowe, sposoby ich wytwarzania, kompozycje farmaceutyczne zawierające te związki oraz ich zastosowanieInfo
- Publication number
- PL3880675T3 PL3880675T3 PL19805569.1T PL19805569T PL3880675T3 PL 3880675 T3 PL3880675 T3 PL 3880675T3 PL 19805569 T PL19805569 T PL 19805569T PL 3880675 T3 PL3880675 T3 PL 3880675T3
- Authority
- PL
- Poland
- Prior art keywords
- compounds
- manufacturing
- methods
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/499—Spiro-condensed pyrazines or piperazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/20—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18205619 | 2018-11-12 | ||
| EP18213016 | 2018-12-17 | ||
| PCT/EP2019/080903 WO2020099341A1 (en) | 2018-11-12 | 2019-11-11 | Antibiotic compounds, methods of manufacturing the same, pharmaceutical compositions containing the same and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3880675T3 true PL3880675T3 (pl) | 2025-02-10 |
Family
ID=68610175
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL19805569.1T PL3880675T3 (pl) | 2018-11-12 | 2019-11-11 | Związki antybiotykowe, sposoby ich wytwarzania, kompozycje farmaceutyczne zawierające te związki oraz ich zastosowanie |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US12545672B2 (pl) |
| EP (1) | EP3880675B1 (pl) |
| JP (1) | JP2022506957A (pl) |
| KR (1) | KR102872166B1 (pl) |
| CN (1) | CN113272302B (pl) |
| AU (1) | AU2019380568B2 (pl) |
| BR (1) | BR112021009106A2 (pl) |
| CA (1) | CA3119390A1 (pl) |
| CL (2) | CL2021001244A1 (pl) |
| DK (1) | DK3880675T3 (pl) |
| ES (1) | ES3009675T3 (pl) |
| FI (1) | FI3880675T3 (pl) |
| HU (1) | HUE069513T2 (pl) |
| IL (2) | IL282950A (pl) |
| LT (1) | LT3880675T (pl) |
| MX (2) | MX2021005535A (pl) |
| PH (1) | PH12021551058A1 (pl) |
| PL (1) | PL3880675T3 (pl) |
| RS (1) | RS66257B1 (pl) |
| SG (1) | SG11202104863RA (pl) |
| SI (1) | SI3880675T1 (pl) |
| SM (1) | SMT202400519T1 (pl) |
| TN (1) | TN2021000092A1 (pl) |
| UA (1) | UA129248C2 (pl) |
| WO (1) | WO2020099341A1 (pl) |
| ZA (1) | ZA202103516B (pl) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2022007412A (es) | 2019-12-19 | 2022-09-19 | Debiopharm Int Sa | Compuestos novedosos y sus usos. |
| WO2022187329A1 (en) * | 2021-03-03 | 2022-09-09 | The Board Of Trustees Of The University Of Illinois | Fabi inhibitors for gram-negative pathogens |
| MX2024000036A (es) | 2021-06-23 | 2024-04-29 | Debiopharm Int Sa | Compuestos novedosos y su uso. |
| WO2025073269A1 (zh) * | 2023-10-07 | 2025-04-10 | 广州白云山医药集团股份有限公司白云山制药总厂 | 一种FabI酶抑制剂及其应用 |
| WO2025078209A1 (en) | 2023-10-09 | 2025-04-17 | Debiopharm International S.A. | Antibiotic compounds for treating bacterial infections |
| WO2025248051A1 (en) | 2024-05-31 | 2025-12-04 | Debiopharm International S.A. | Acrylamide derivatives for the treatment of diseases associated with pathogenic bacteria in the gastrointestinal system |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6921763B2 (en) | 1999-09-17 | 2005-07-26 | Abbott Laboratories | Pyrazolopyrimidines as therapeutic agents |
| ECSP003699A (es) | 1999-10-08 | 2002-04-23 | Smithkline Beecham Corp | Inhibidores de fab i |
| DE60230934D1 (de) | 2001-04-06 | 2009-03-05 | Affinium Pharm Inc | Fab-i-inhibitoren |
| WO2004082586A2 (en) | 2003-03-17 | 2004-09-30 | Affinium Pharmaceuticals, Inc. | Phamaceutical compositions comprising inhibitors of fab i and further antibiotics |
| US8450307B2 (en) * | 2004-06-04 | 2013-05-28 | Affinium Pharmaceuticals, Inc. | Therapeutic agents, and methods of making and using the same |
| CN101415701A (zh) | 2005-12-05 | 2009-04-22 | Affinium医药公司 | 作为fabi抑制剂的杂环丙烯酰胺化合物和抗菌剂 |
| CA2632476A1 (en) * | 2005-12-05 | 2007-06-14 | Affinium Pharmaceuticals, Inc. | Heterocyclylacrylamide compounds as fabi inhibitors and antibacterial agents |
| US7601716B2 (en) | 2006-05-01 | 2009-10-13 | Cephalon, Inc. | Pyridopyrazines and derivatives thereof as ALK and c-Met inhibitors |
| EP2687533B1 (en) | 2006-07-20 | 2017-07-19 | Debiopharm International SA | Acrylamide derivatives as FAB I inhibitors |
| WO2008098374A1 (en) | 2007-02-16 | 2008-08-21 | Affinium Pharmaceuticals, Inc. | Salts, prodrugs and polymorphs of fab i inhibitors |
| JO3611B1 (ar) | 2011-08-10 | 2020-08-27 | Janssen Sciences Ireland Uc | سايكلو بنتا (سي (بيرول 4,3 ثاني هيدرو 1 hمستبدله [8,1] نافثيريدينونات مضادة للجراثيم |
| US9115149B2 (en) | 2011-09-19 | 2015-08-25 | Vitas Pharma Research Private Limited | Heterocyclic compounds as inhibitors of fatty acid biosysnthesis for bacterial infections |
| WO2013080222A1 (en) | 2011-12-02 | 2013-06-06 | Aurigene Discovery Technologies Limited | Substituted pyridine derivatives as fabi inhibitors |
| KR101720885B1 (ko) | 2012-06-19 | 2017-03-28 | 데비오팜 인터네셔날 에스 에이 | (e)-n-메틸-n-((3-메틸벤조푸란-2-일)메틸)-3-(7-옥소-5,6,7,8-테트라히드로-1,8-나프티리딘-3-일)아크릴아미드의전구약물 유도체 |
| EA201590339A1 (ru) | 2012-08-10 | 2015-06-30 | Янссен Сайенсиз Айрлэнд Юси | Новые антибактериальные соединения |
| DK3406633T3 (da) | 2013-07-25 | 2022-03-28 | Cytomx Therapeutics Inc | Multispecifikke antistoffer, multispecifikke aktiverbare antistoffer og fremgangsmåder til anvendelse heraf |
| CN104341388B (zh) | 2013-10-16 | 2017-03-22 | 北京诺诚健华医药科技有限公司 | 芳香族酰胺类衍生物、其制备方法及其在医药上的应用 |
| AU2015292406B2 (en) | 2014-07-25 | 2021-03-11 | Cytomx Therapeutics, Inc | Anti-CD3 antibodies, activatable anti-CD3 antibodies, multispecific anti-CD3 antibodies, multispecific activatable anti-CD3 antibodies, and methods of using the same |
| MX2022007412A (es) | 2019-12-19 | 2022-09-19 | Debiopharm Int Sa | Compuestos novedosos y sus usos. |
-
2019
- 2019-11-11 CA CA3119390A patent/CA3119390A1/en active Pending
- 2019-11-11 PL PL19805569.1T patent/PL3880675T3/pl unknown
- 2019-11-11 UA UAA202103198A patent/UA129248C2/uk unknown
- 2019-11-11 KR KR1020217018050A patent/KR102872166B1/ko active Active
- 2019-11-11 MX MX2021005535A patent/MX2021005535A/es unknown
- 2019-11-11 AU AU2019380568A patent/AU2019380568B2/en active Active
- 2019-11-11 WO PCT/EP2019/080903 patent/WO2020099341A1/en not_active Ceased
- 2019-11-11 DK DK19805569.1T patent/DK3880675T3/da active
- 2019-11-11 HU HUE19805569A patent/HUE069513T2/hu unknown
- 2019-11-11 CN CN201980088149.0A patent/CN113272302B/zh active Active
- 2019-11-11 SG SG11202104863RA patent/SG11202104863RA/en unknown
- 2019-11-11 ES ES19805569T patent/ES3009675T3/es active Active
- 2019-11-11 EP EP19805569.1A patent/EP3880675B1/en active Active
- 2019-11-11 FI FIEP19805569.1T patent/FI3880675T3/fi active
- 2019-11-11 BR BR112021009106-8A patent/BR112021009106A2/pt unknown
- 2019-11-11 SI SI201930867T patent/SI3880675T1/sl unknown
- 2019-11-11 US US17/292,600 patent/US12545672B2/en active Active
- 2019-11-11 RS RS20241349A patent/RS66257B1/sr unknown
- 2019-11-11 TN TNP/2021/000092A patent/TN2021000092A1/en unknown
- 2019-11-11 SM SM20240519T patent/SMT202400519T1/it unknown
- 2019-11-11 LT LTEPPCT/EP2019/080903T patent/LT3880675T/lt unknown
- 2019-11-11 JP JP2021525117A patent/JP2022506957A/ja active Pending
-
2021
- 2021-05-05 IL IL282950A patent/IL282950A/en unknown
- 2021-05-07 PH PH12021551058A patent/PH12021551058A1/en unknown
- 2021-05-11 MX MX2024010625A patent/MX2024010625A/es unknown
- 2021-05-12 CL CL2021001244A patent/CL2021001244A1/es unknown
- 2021-05-24 ZA ZA2021/03516A patent/ZA202103516B/en unknown
-
2022
- 2022-12-22 CL CL2022003703A patent/CL2022003703A1/es unknown
-
2024
- 2024-04-02 IL IL311894A patent/IL311894B1/en unknown
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