PL3813799T3 - Preparat farmaceutyczny o zwiększonej rozpuszczalności i biodostępności - Google Patents

Preparat farmaceutyczny o zwiększonej rozpuszczalności i biodostępności

Info

Publication number
PL3813799T3
PL3813799T3 PL19735288.3T PL19735288T PL3813799T3 PL 3813799 T3 PL3813799 T3 PL 3813799T3 PL 19735288 T PL19735288 T PL 19735288T PL 3813799 T3 PL3813799 T3 PL 3813799T3
Authority
PL
Poland
Prior art keywords
bioavailability
pharmaceutical formulation
improved solubility
solubility
improved
Prior art date
Application number
PL19735288.3T
Other languages
English (en)
Inventor
José María LAGARÓN CABELLO
Cristina PRIETO LÓPEZ
José Manuel VALLE BAZ
David GALÁN NEVADO
Julia Hrakovsky
Original Assignee
Consejo Superior De Investigaciones Cientificas (Csic)
Bioinicia, S.L.
Zakłady Farmaceutyczne POLPHARMA Spółka Akcyjna
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consejo Superior De Investigaciones Cientificas (Csic), Bioinicia, S.L., Zakłady Farmaceutyczne POLPHARMA Spółka Akcyjna filed Critical Consejo Superior De Investigaciones Cientificas (Csic)
Publication of PL3813799T3 publication Critical patent/PL3813799T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y40/00—Manufacture or treatment of nanostructures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL19735288.3T 2018-06-29 2019-06-28 Preparat farmaceutyczny o zwiększonej rozpuszczalności i biodostępności PL3813799T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18382484.6A EP3586827A1 (en) 2018-06-29 2018-06-29 Pharmaceutical formulation with improved solubility and bioavailability
PCT/EP2019/067342 WO2020002609A1 (en) 2018-06-29 2019-06-28 Pharmaceutical formulation with improved solubility and bioavailability

Publications (1)

Publication Number Publication Date
PL3813799T3 true PL3813799T3 (pl) 2024-09-02

Family

ID=62842044

Family Applications (1)

Application Number Title Priority Date Filing Date
PL19735288.3T PL3813799T3 (pl) 2018-06-29 2019-06-28 Preparat farmaceutyczny o zwiększonej rozpuszczalności i biodostępności

Country Status (8)

Country Link
US (2) US20210267898A1 (pl)
EP (2) EP3586827A1 (pl)
CA (1) CA3104579A1 (pl)
EA (1) EA202092922A1 (pl)
ES (1) ES2978725T3 (pl)
HU (1) HUE066663T2 (pl)
PL (1) PL3813799T3 (pl)
WO (1) WO2020002609A1 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3902528A1 (en) * 2018-12-19 2021-11-03 Friulchem SpA Process for the manufacture of a tablet of rifaximin and tablet of rifaximin
CL2021003207A1 (es) * 2021-12-02 2023-07-14 B Morph Spa Aditivo fotocatalítico para polímeros; material polimérico con propiedades fotocatalíticas; método para elaborarlo; y uso.
CN114524769B (zh) * 2022-02-14 2023-10-24 中国药科大学 塞来昔布-卡马西平共晶、制备方法、药物组合物和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2608942B1 (fr) 1986-12-31 1991-01-11 Centre Nat Rech Scient Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanocapsules
EP0862420A4 (en) 1995-10-13 1999-11-03 Penn State Res Found SYNTHESIS OF DRUG SPRAY DRUG NANOPARTICLES
US6966990B2 (en) 2002-10-11 2005-11-22 Ferro Corporation Composite particles and method for preparing
US20050008704A1 (en) 2003-07-11 2005-01-13 Ray Anup Kumar Pharmaceutical composition for solubility enhancement of hydrophobic drugs
WO2015120861A1 (en) 2014-02-14 2015-08-20 University Of Copenhagen Method for producing nano-embedded microparticles
AU2015353413A1 (en) * 2014-11-25 2017-05-11 Nanocopoeia, Llc Amorphous nanoparticles prepared by electrospraying
ES2674808B1 (es) * 2016-12-30 2019-04-11 Bioinicia S L Instalacion y procedimiento de encapsulado industrial de sustanciastermolabiles

Also Published As

Publication number Publication date
WO2020002609A1 (en) 2020-01-02
EA202092922A1 (ru) 2021-06-10
HUE066663T2 (hu) 2024-09-28
CA3104579A1 (en) 2020-01-02
EP3813799B1 (en) 2024-02-21
ES2978725T3 (es) 2024-09-18
EP3586827A1 (en) 2020-01-01
US20210267898A1 (en) 2021-09-02
EP3813799A1 (en) 2021-05-05
EP3813799C0 (en) 2024-02-21
US12419838B2 (en) 2025-09-23
US20230040719A1 (en) 2023-02-09

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