PL3801460T3 - Sole amlodypiny do stosowania miejscowego w leczeniu chorób odbytu i odbytnicy - Google Patents

Sole amlodypiny do stosowania miejscowego w leczeniu chorób odbytu i odbytnicy

Info

Publication number
PL3801460T3
PL3801460T3 PL19766349.5T PL19766349T PL3801460T3 PL 3801460 T3 PL3801460 T3 PL 3801460T3 PL 19766349 T PL19766349 T PL 19766349T PL 3801460 T3 PL3801460 T3 PL 3801460T3
Authority
PL
Poland
Prior art keywords
anus
rectum
diseases
treatment
topical use
Prior art date
Application number
PL19766349.5T
Other languages
English (en)
Inventor
László RITTER
László HORNOK
Péter MATYUS
Romána ZELKO
Andrea UJHELYI
Richárd KARPATI
Tamás SOLYMOSI
Hristos Glavinas
Original Assignee
Tavanta Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tavanta Therapeutics, Inc. filed Critical Tavanta Therapeutics, Inc.
Publication of PL3801460T3 publication Critical patent/PL3801460T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/44221,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0031Rectum, anus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL19766349.5T 2018-06-01 2019-05-29 Sole amlodypiny do stosowania miejscowego w leczeniu chorób odbytu i odbytnicy PL3801460T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862679137P 2018-06-01 2018-06-01
US201962822400P 2019-03-22 2019-03-22
PCT/IB2019/000689 WO2019229535A2 (en) 2018-06-01 2019-05-29 Topical amlodipine salts for the treatment of anorectal diseases

Publications (1)

Publication Number Publication Date
PL3801460T3 true PL3801460T3 (pl) 2025-09-08

Family

ID=67928855

Family Applications (1)

Application Number Title Priority Date Filing Date
PL19766349.5T PL3801460T3 (pl) 2018-06-01 2019-05-29 Sole amlodypiny do stosowania miejscowego w leczeniu chorób odbytu i odbytnicy

Country Status (18)

Country Link
US (4) US11197848B2 (pl)
EP (1) EP3801460B1 (pl)
JP (1) JP7530354B2 (pl)
KR (1) KR20210023908A (pl)
CN (1) CN112423736A (pl)
AU (1) AU2019276832B2 (pl)
BR (1) BR112020024395A2 (pl)
CA (1) CA3102228A1 (pl)
CO (1) CO2020016480A2 (pl)
CR (1) CR20200630A (pl)
ES (1) ES3030705T3 (pl)
HU (1) HUE072422T2 (pl)
IL (1) IL279121B2 (pl)
MX (1) MX2020012949A (pl)
NZ (1) NZ771464A (pl)
PL (1) PL3801460T3 (pl)
SG (1) SG11202012365QA (pl)
WO (1) WO2019229535A2 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3102228A1 (en) 2018-06-01 2019-12-05 Tavanta Therapeutics Hungary Incorporated Topical amlodipine salts for the treatment of anorectal diseases
ES2978421T3 (es) * 2019-12-09 2024-09-12 Futura Medical Developments Ltd Composición tópica y métodos para medir la capacidad de enfriamiento de una composición tópica
US11253474B1 (en) 2021-02-01 2022-02-22 Liqmeds Worldwide Limited Pharmaceutical solution of amlodipine

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT89837B (pt) 1988-02-29 1994-01-31 Pfizer Processo para a preparacao de composicoes para aumentar o fluxo transdermico contendo uma 1-alquilazaciclo-heptan-2-ona ou uma cis-olefina
WO1995006466A1 (en) 1993-09-01 1995-03-09 Koren Laboratories Pty. Limited Treatment of anorectal disorders
US8048875B1 (en) 1997-02-24 2011-11-01 S.L.A. Pharma Ag Topical pharmaceutical composition comprising a cholinergic agent or a calcium channel blocker
EP1250927A3 (en) * 1997-02-24 2003-03-26 S.L.A. Pharma AG Pharmaceutical composition for topical application comprising nifedipine
WO1999018957A1 (en) * 1998-03-26 1999-04-22 Reddy-Cheminor, Inc. Stable pharmaceutical composition containing amlodipine besylate and atenolol
US6391869B1 (en) 1998-12-14 2002-05-21 Cellergy Pharmaceuticals, Inc. Compositions and methods for the treatment of anorectal disorders
IL143726A0 (en) * 1998-12-14 2002-04-21 Cellegy Pharma Inc A pharmaceutical composition containing a nitric oxide donor
IL129102A0 (en) * 1999-03-22 2000-02-17 J P M E D Ltd An emulsion
IL137275A0 (en) 2000-07-12 2001-07-24 Yosefus Azaria Pharmaceutical composition for the treatment of anal fissures
US8425892B2 (en) 2001-10-29 2013-04-23 Columbia Laboratories, Inc. Extended, controlled-release pharmaceutical compositions using charged polymers
WO2003075851A2 (en) 2002-03-06 2003-09-18 Cellegy Pharmaceuticals, Inc. Compositions and methods for the treatment of anorectal disorders
EP1893396A2 (en) * 2005-05-09 2008-03-05 Foamix Ltd. Foamable vehicle and pharmaceutical compositions thereof
WO2008022032A2 (en) 2006-08-11 2008-02-21 Solvay Pharmaceuticals, Inc. Topical pharmaceutical compositions comprising calcium-channel blocker and method of using same
EP2061463A4 (en) * 2006-09-01 2010-01-20 Moberg Derma Ab TOPICAL COMPOSITION WITH A DIHYDROPYRIDINCALCIUM ANTAGONIST
EP2167045B1 (en) * 2007-06-08 2017-08-09 University of Virginia Patent Foundation Topical poloxamer formulations for enhancing microvascular flow: compositions and uses thereof
JP5072748B2 (ja) * 2007-07-10 2012-11-14 株式会社 メドレックス アムロジピンの安定な液剤とゼリー剤
CN101468001A (zh) * 2007-12-29 2009-07-01 北京瑞康医药技术有限公司 含有氨氯地平系列盐和他汀类药物的治疗组合物
US8686040B2 (en) 2008-03-31 2014-04-01 Rdd Pharma Ltd. Method for treating anal pruritis and other perianal disorders
JP2009256216A (ja) * 2008-04-14 2009-11-05 Towa Yakuhin Kk 溶液状態で安定なアムロジピンベシル酸塩内服用液剤
AU2009310437A1 (en) * 2008-10-31 2010-05-06 Moberg Derma Ab Topical composition comprising a combination of at least two penetration enhancing agents
GB0906868D0 (en) * 2009-04-21 2009-06-03 Rabin Bennie Amlodipine salt compositions
WO2011075655A1 (en) 2009-12-18 2011-06-23 Exodos Life Sciences Limited Partnership Methods and compositions for treating peripheral vascular disease
US10471131B2 (en) * 2012-01-19 2019-11-12 Hybrid Medical, Llc Topical therapeutic formulations
JP2015517518A (ja) 2012-05-17 2015-06-22 コントラクト ファーマシューティカルズ リミテッド カルシウムチャネル遮断薬の非イオン性ベシクル製剤
RU2592366C2 (ru) 2013-07-22 2016-07-20 Общество с ограниченной ответственностью "ХИЛИНГ ФАРМ" Фармакологическая композиция для лечения проктологических заболеваний (варианты)
WO2015051336A1 (en) 2013-10-03 2015-04-09 David Wise Compositions and methods for treating pelvic pain and other conditions
WO2016118040A1 (ru) 2015-01-21 2016-07-28 ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "НоваМедика" Гель, содержащий нифедипин и лидокаина гидрохлорид, его применение и способ приготовления с использованием нанотехнологий
IT201800002413A1 (it) 2018-02-05 2019-08-05 Carmine Antropoli "composizione a base di nifedipina per uso nel trattamento delle ragadi anali e proctalgie"
BR102018008324A2 (pt) 2018-04-25 2019-11-05 Laboratorios Ferring Ltda composição farmacêutica de uso tópico e processo de fabricação de composição farmacêutica de uso tópico
WO2019226542A1 (en) 2018-05-22 2019-11-28 Weinberg Assa Methods for prevention and treatment of pressure ulcers caused by ischemia using contact vasodilators
CA3102228A1 (en) 2018-06-01 2019-12-05 Tavanta Therapeutics Hungary Incorporated Topical amlodipine salts for the treatment of anorectal diseases

Also Published As

Publication number Publication date
US11766428B2 (en) 2023-09-26
IL279121B2 (en) 2024-06-01
US20230414591A1 (en) 2023-12-28
EP3801460B1 (en) 2025-03-12
EP3801460C0 (en) 2025-03-12
WO2019229535A3 (en) 2020-01-30
HUE072422T2 (hu) 2025-11-28
NZ771464A (en) 2024-12-20
AU2019276832B2 (en) 2024-08-15
JP2021526554A (ja) 2021-10-07
US20250064790A1 (en) 2025-02-27
KR20210023908A (ko) 2021-03-04
CO2020016480A2 (es) 2021-03-19
IL279121B1 (en) 2024-02-01
CR20200630A (es) 2021-05-26
US20220000850A1 (en) 2022-01-06
US11197848B2 (en) 2021-12-14
EP3801460A2 (en) 2021-04-14
SG11202012365QA (en) 2021-01-28
CA3102228A1 (en) 2019-12-05
IL279121A (en) 2021-01-31
WO2019229535A2 (en) 2019-12-05
US20190365732A1 (en) 2019-12-05
MX2020012949A (es) 2021-05-12
CN112423736A (zh) 2021-02-26
AU2019276832A1 (en) 2021-01-21
JP7530354B2 (ja) 2024-08-07
ES3030705T3 (en) 2025-07-01
BR112020024395A2 (pt) 2021-03-02

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