PL3697794T3 - Stałe postacie 3-(5-fluorobenzofuran-3-ylo)-4-(5-metylo-5h-[1,3]dioksolo[4,5-f]indol-7-ilo)pirolo-2,5-dionu - Google Patents
Stałe postacie 3-(5-fluorobenzofuran-3-ylo)-4-(5-metylo-5h-[1,3]dioksolo[4,5-f]indol-7-ilo)pirolo-2,5-dionuInfo
- Publication number
- PL3697794T3 PL3697794T3 PL18797367.2T PL18797367T PL3697794T3 PL 3697794 T3 PL3697794 T3 PL 3697794T3 PL 18797367 T PL18797367 T PL 18797367T PL 3697794 T3 PL3697794 T3 PL 3697794T3
- Authority
- PL
- Poland
- Prior art keywords
- fluorobenzofuran
- dioxolo
- pyrrol
- indol
- dione
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/056—Ortho-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762572603P | 2017-10-16 | 2017-10-16 | |
| PCT/US2018/056083 WO2019079299A1 (en) | 2017-10-16 | 2018-10-16 | SOLID FORMS OF 3- (5-FLUOROBENZOFURAN-3-YL) -4- (5-METHYL-5H- [1,3] DIOXOLO [4,5-F] INDOL-7-YL) PYRROLE-2,5-DIONE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3697794T3 true PL3697794T3 (pl) | 2026-04-07 |
Family
ID=64110166
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL18797367.2T PL3697794T3 (pl) | 2017-10-16 | 2018-10-16 | Stałe postacie 3-(5-fluorobenzofuran-3-ylo)-4-(5-metylo-5h-[1,3]dioksolo[4,5-f]indol-7-ilo)pirolo-2,5-dionu |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US11407759B2 (enExample) |
| EP (2) | EP4740944A2 (enExample) |
| JP (2) | JP7776258B2 (enExample) |
| KR (1) | KR102891811B1 (enExample) |
| CN (1) | CN111315748B (enExample) |
| AU (1) | AU2018352384B2 (enExample) |
| CA (1) | CA3074037A1 (enExample) |
| DK (1) | DK3697794T3 (enExample) |
| ES (1) | ES3064009T3 (enExample) |
| FI (1) | FI3697794T3 (enExample) |
| IL (1) | IL273920B2 (enExample) |
| MX (1) | MX2020003431A (enExample) |
| PL (1) | PL3697794T3 (enExample) |
| PT (1) | PT3697794T (enExample) |
| WO (1) | WO2019079299A1 (enExample) |
| ZA (1) | ZA202002740B (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2020003431A (es) * | 2017-10-16 | 2020-07-29 | Actuate Therapeutics Inc | Formas solidas de 3-(5-fluorobenzofuran-3-il)-4-(5-metil-5h-[1,3]d ioxolo[4,5-f]indol-7-il)pirrol- 2,5-diona. |
| CN112437663A (zh) * | 2018-05-17 | 2021-03-02 | 开动疗法公司 | 用β型糖原合酶激酶3抑制剂治疗特发性肺纤维化 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2446269T3 (es) | 2006-12-19 | 2014-03-06 | The Board Of Trustees Of The University Of Illinois | 3-Benzofuranil-4-indolil-maleimidas como potentes inhibidores de GSK-3 para trastornos neurodegenerativos |
| FI3665176T3 (fi) | 2017-08-11 | 2024-03-20 | Actuate Therapeutics Inc | 3-(5-fluoribentsofuran-3-yyli)-4-(5-metyyli-5h-[1,3]dioksolo[4,5-f]indol-7-yyli)pyrroli-2,5-dionin kiinteitä muotoja |
| MX2020003431A (es) * | 2017-10-16 | 2020-07-29 | Actuate Therapeutics Inc | Formas solidas de 3-(5-fluorobenzofuran-3-il)-4-(5-metil-5h-[1,3]d ioxolo[4,5-f]indol-7-il)pirrol- 2,5-diona. |
-
2018
- 2018-10-16 MX MX2020003431A patent/MX2020003431A/es unknown
- 2018-10-16 JP JP2020521319A patent/JP7776258B2/ja active Active
- 2018-10-16 PL PL18797367.2T patent/PL3697794T3/pl unknown
- 2018-10-16 AU AU2018352384A patent/AU2018352384B2/en active Active
- 2018-10-16 ES ES18797367T patent/ES3064009T3/es active Active
- 2018-10-16 PT PT187973672T patent/PT3697794T/pt unknown
- 2018-10-16 KR KR1020207013947A patent/KR102891811B1/ko active Active
- 2018-10-16 IL IL273920A patent/IL273920B2/en unknown
- 2018-10-16 DK DK18797367.2T patent/DK3697794T3/da active
- 2018-10-16 CA CA3074037A patent/CA3074037A1/en active Pending
- 2018-10-16 EP EP25225740.7A patent/EP4740944A2/en active Pending
- 2018-10-16 WO PCT/US2018/056083 patent/WO2019079299A1/en not_active Ceased
- 2018-10-16 CN CN201880066706.4A patent/CN111315748B/zh active Active
- 2018-10-16 EP EP18797367.2A patent/EP3697794B1/en active Active
- 2018-10-16 US US16/755,903 patent/US11407759B2/en active Active
- 2018-10-16 FI FIEP18797367.2T patent/FI3697794T3/fi active
-
2020
- 2020-05-13 ZA ZA2020/02740A patent/ZA202002740B/en unknown
-
2022
- 2022-07-01 US US17/855,847 patent/US12116374B2/en active Active
-
2023
- 2023-09-19 JP JP2023151499A patent/JP2024001040A/ja active Pending
-
2024
- 2024-09-10 US US18/830,117 patent/US20250115615A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ZA202002740B (en) | 2025-12-17 |
| JP2024001040A (ja) | 2024-01-09 |
| WO2019079299A1 (en) | 2019-04-25 |
| JP2020536944A (ja) | 2020-12-17 |
| IL273920B1 (en) | 2025-03-01 |
| IL273920B2 (en) | 2025-07-01 |
| ES3064009T3 (en) | 2026-04-22 |
| KR20200100615A (ko) | 2020-08-26 |
| US12116374B2 (en) | 2024-10-15 |
| CN111315748B (zh) | 2023-06-27 |
| US20250115615A1 (en) | 2025-04-10 |
| AU2018352384A1 (en) | 2020-05-21 |
| KR102891811B1 (ko) | 2025-11-28 |
| US11407759B2 (en) | 2022-08-09 |
| IL273920A (en) | 2020-05-31 |
| US20220348591A1 (en) | 2022-11-03 |
| DK3697794T3 (da) | 2026-02-02 |
| CA3074037A1 (en) | 2019-04-25 |
| US20200239489A1 (en) | 2020-07-30 |
| EP3697794B1 (en) | 2025-12-24 |
| MX2020003431A (es) | 2020-07-29 |
| PT3697794T (pt) | 2026-03-04 |
| BR112020007538A2 (pt) | 2020-09-24 |
| CN111315748A (zh) | 2020-06-19 |
| JP7776258B2 (ja) | 2025-11-26 |
| EP4740944A2 (en) | 2026-05-13 |
| AU2018352384B2 (en) | 2023-12-21 |
| EP3697794A1 (en) | 2020-08-26 |
| FI3697794T3 (fi) | 2026-02-10 |
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