PL3625339T3 - Modyfikacje w enzymówach dekarboksylazy lizynowej - Google Patents
Modyfikacje w enzymówach dekarboksylazy lizynowejInfo
- Publication number
- PL3625339T3 PL3625339T3 PL17910224.9T PL17910224T PL3625339T3 PL 3625339 T3 PL3625339 T3 PL 3625339T3 PL 17910224 T PL17910224 T PL 17910224T PL 3625339 T3 PL3625339 T3 PL 3625339T3
- Authority
- PL
- Poland
- Prior art keywords
- modifications
- lysine decarboxylase
- decarboxylase enzymes
- enzymes
- lysine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/001—Amines; Imines
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y401/00—Carbon-carbon lyases (4.1)
- C12Y401/01—Carboxy-lyases (4.1.1)
- C12Y401/01018—Lysine decarboxylase (4.1.1.18)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2017/084540 WO2018209563A1 (en) | 2017-05-16 | 2017-05-16 | Modifications to lysine decarboxylase enzymes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3625339T3 true PL3625339T3 (pl) | 2026-01-19 |
Family
ID=64273117
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL17910224.9T PL3625339T3 (pl) | 2017-05-16 | 2017-05-16 | Modyfikacje w enzymówach dekarboksylazy lizynowej |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US11512302B2 (pl) |
| EP (1) | EP3625339B1 (pl) |
| CN (1) | CN110546255B (pl) |
| ES (1) | ES3053013T3 (pl) |
| PL (1) | PL3625339T3 (pl) |
| WO (1) | WO2018209563A1 (pl) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113881719A (zh) * | 2020-07-02 | 2022-01-04 | 中国科学院过程工程研究所 | 一种全细胞催化合成1,5-戊二胺的方法 |
| CN113881657B (zh) * | 2020-07-02 | 2024-02-02 | 中国科学院过程工程研究所 | 一种用于合成戊二胺的赖氨酸脱羧酶及其应用 |
| CN114621984B (zh) * | 2020-12-14 | 2025-01-28 | 中国科学院过程工程研究所 | 一种离子液体强化赖氨酸脱羧酶合成1,5-戊二胺的方法 |
| CN115125229B (zh) * | 2021-03-25 | 2023-11-14 | 中国科学院过程工程研究所 | 一种用于合成戊二胺的赖氨酸脱羧酶突变体 |
| CN116254253B (zh) * | 2022-11-11 | 2024-06-28 | 浙大宁波理工学院 | 一种通过dna合成改组组合突变获得的谷氨酸脱羧酶突变体及应用 |
| CN118516339A (zh) * | 2023-02-18 | 2024-08-20 | 宁波酶赛生物工程有限公司 | 一种制备1,5-戊二胺的工程化赖氨酸脱羧酶 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4551433A (en) | 1981-05-18 | 1985-11-05 | Genentech, Inc. | Microbial hybrid promoters |
| WO2013108859A1 (ja) * | 2012-01-18 | 2013-07-25 | 三井化学株式会社 | １，５－ペンタメチレンジアミンの製造方法、変異型リジン脱炭酸酵素、１，５－ペンタメチレンジイソシアネートの製造方法およびポリイソシアネート組成物の製造方法 |
| CN103789292B (zh) * | 2013-12-26 | 2015-10-21 | 南京工业大学 | 一种赖氨酸脱羧酶、制备方法及其应用 |
| CN104762336B (zh) | 2014-01-06 | 2019-10-29 | 上海凯赛生物技术股份有限公司 | 1,5-戊二胺的制备方法 |
| JP6460092B2 (ja) | 2014-03-11 | 2019-01-30 | 味の素株式会社 | 熱安定性向上リジン脱炭酸酵素変異体を用いる１，５−ペンタジアミンの製造方法 |
| EP3161125B1 (en) * | 2014-06-26 | 2021-02-17 | Cathay Biotech Inc. | Expression of polypeptides involved in lysine decarboxylation, and methods and applications thereof |
| ES2871097T3 (es) * | 2015-01-30 | 2021-10-28 | Cathay Biotech Inc | Expresión de polipéptidos de Klebsiella oxytoca implicados en la descarboxilación de lisina, y métodos y aplicaciones de los mismos |
| KR101791837B1 (ko) | 2015-08-06 | 2017-10-31 | 서울대학교산학협력단 | 라이신 디카르복실라아제의 변이주 개발 방법 및 그의 응용 |
-
2017
- 2017-05-16 US US16/614,265 patent/US11512302B2/en active Active
- 2017-05-16 CN CN201780089675.XA patent/CN110546255B/zh active Active
- 2017-05-16 PL PL17910224.9T patent/PL3625339T3/pl unknown
- 2017-05-16 ES ES17910224T patent/ES3053013T3/es active Active
- 2017-05-16 WO PCT/CN2017/084540 patent/WO2018209563A1/en not_active Ceased
- 2017-05-16 EP EP17910224.9A patent/EP3625339B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3625339B1 (en) | 2025-09-03 |
| US11512302B2 (en) | 2022-11-29 |
| EP3625339A4 (en) | 2021-01-20 |
| US20210155962A1 (en) | 2021-05-27 |
| EP3625339A1 (en) | 2020-03-25 |
| CN110546255A (zh) | 2019-12-06 |
| CN110546255B (zh) | 2023-07-04 |
| ES3053013T3 (en) | 2026-01-16 |
| WO2018209563A1 (en) | 2018-11-22 |
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