PL356031A1 - Pochodne indolu jako antagoniści receptora MCP-1 - Google Patents
Pochodne indolu jako antagoniści receptora MCP-1Info
- Publication number
- PL356031A1 PL356031A1 PL01356031A PL35603101A PL356031A1 PL 356031 A1 PL356031 A1 PL 356031A1 PL 01356031 A PL01356031 A PL 01356031A PL 35603101 A PL35603101 A PL 35603101A PL 356031 A1 PL356031 A1 PL 356031A1
- Authority
- PL
- Poland
- Prior art keywords
- mcp
- receptor antagonists
- indole derivatives
- indole
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0000626.2A GB0000626D0 (en) | 2000-01-13 | 2000-01-13 | Chemical compounds |
| PCT/GB2001/000069 WO2001051466A1 (en) | 2000-01-13 | 2001-01-11 | Indole derivatives as mcp-1 receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL356031A1 true PL356031A1 (pl) | 2004-06-14 |
Family
ID=9883551
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL01356031A PL356031A1 (pl) | 2000-01-13 | 2001-01-11 | Pochodne indolu jako antagoniści receptora MCP-1 |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US20030144339A1 (pl) |
| EP (1) | EP1252142A1 (pl) |
| JP (1) | JP2003519683A (pl) |
| KR (1) | KR20020064375A (pl) |
| CN (1) | CN1395565A (pl) |
| AR (1) | AR026839A1 (pl) |
| AU (1) | AU780992B2 (pl) |
| BG (1) | BG106894A (pl) |
| BR (1) | BR0107404A (pl) |
| CA (1) | CA2393592A1 (pl) |
| CO (1) | CO5271703A1 (pl) |
| EE (1) | EE200200394A (pl) |
| GB (1) | GB0000626D0 (pl) |
| HK (1) | HK1049486A1 (pl) |
| HU (1) | HUP0300694A3 (pl) |
| IL (1) | IL150272A0 (pl) |
| IS (1) | IS6429A (pl) |
| MX (1) | MXPA02006611A (pl) |
| NO (1) | NO20023380L (pl) |
| NZ (1) | NZ519312A (pl) |
| PL (1) | PL356031A1 (pl) |
| RU (1) | RU2002121636A (pl) |
| SK (1) | SK10072002A3 (pl) |
| WO (1) | WO2001051466A1 (pl) |
| ZA (1) | ZA200204354B (pl) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9716657D0 (en) | 1997-08-07 | 1997-10-15 | Zeneca Ltd | Chemical compounds |
| GB9902461D0 (en) | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
| WO2004069809A1 (en) | 2003-02-03 | 2004-08-19 | Janssen Pharmaceutica N.V. | Mercaptoimidazoles as ccr2 receptor antagonists |
| EP1811007B1 (en) * | 2004-09-13 | 2010-03-31 | Kureha Corporation | Thermally foaming microsphere, method for production thereof, use thereof, composition containing the same, and article |
| ATE448230T1 (de) | 2005-12-09 | 2009-11-15 | Hoffmann La Roche | Für die behandlung von obesitas geeignete tricyclische amidderivate |
| US20080076120A1 (en) * | 2006-09-14 | 2008-03-27 | Millennium Pharmaceuticals, Inc. | Methods for the identification, evaluation and treatment of patients having CC-Chemokine receptor 2 (CCR-2) mediated disorders |
| US7507736B2 (en) | 2007-02-07 | 2009-03-24 | Hoffmann-La Roche Inc. | Indol-2-yl-piperazin-1-yl-methanone derivatives |
| JP5496876B2 (ja) * | 2007-04-16 | 2014-05-21 | アッヴィ・インコーポレイテッド | ７−置換されていないインドール系Ｍｃｌ−１阻害薬 |
| WO2023224981A1 (en) * | 2022-05-17 | 2023-11-23 | Inipharm, Inc. | Hsd17b13 inhibitors and uses thereof |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4529724A (en) * | 1983-10-11 | 1985-07-16 | Mcneilab, Inc. | 6H-indolo[2,1-c][1,4]benzodiazepines and 12-oxo derivatives useful as antihypertensives |
| DE3907388A1 (de) * | 1989-03-08 | 1990-09-13 | Kali Chemie Pharma Gmbh | Verfahren zur herstellung von indolcarbonsaeurederivaten |
| US5272145A (en) * | 1989-08-22 | 1993-12-21 | Merck Frosst Canada, Inc. | (Quinolin-2-ylmethoxy)indoles as inhibitors of the biosynthesis of leukotrienes |
| US5081145A (en) * | 1990-02-01 | 1992-01-14 | Merck Frosst Canada, Inc. | Indole-2-alkanoic acids compositions of and anti allergic use thereof |
| US5308850A (en) * | 1991-09-30 | 1994-05-03 | Merck Frosst Canada, Inc. | (Bicyclic-hetero-arylmethoxy)indoles as inhibitors of leukotriene biosynthesis |
| US5273980A (en) * | 1991-09-30 | 1993-12-28 | Merck Frosst Canada Inc. | Bicyclic-azaarylmethoxy) indoles as inhibitors of leukotriene biosynthesis |
| US5290798A (en) * | 1991-09-30 | 1994-03-01 | Merck Frosst Canada, Inc. | (hetero-arylmethoxy)indoles as inhibitors of leukotriene biosynthesis |
| US5190968A (en) * | 1991-09-30 | 1993-03-02 | Merck Frosst Canada, Inc. | (Polycyclic-arylmethoxy) indoles as inhibitors of leukotriene biosynthesis |
| US5389650A (en) * | 1991-09-30 | 1995-02-14 | Merck Frosst Canada, Inc. | (Azaarylmethoxy)indoles as inhibitors of leukotriene biosynthesis |
| US5288743A (en) * | 1992-11-20 | 1994-02-22 | Abbott Laboratories | Indole carboxylate derivatives which inhibit leukotriene biosynthesis |
| US5852046A (en) * | 1993-08-03 | 1998-12-22 | Hoechst Aktiengesellschaft | Benzo-fused heterocyclic compounds having a 5-membered ring processes for their preparation their use as medicaments their use as diagnostic agents and medicaments containing them |
| US5686481A (en) * | 1993-12-21 | 1997-11-11 | Smithkline Beecham Corporation | Endothelin receptor antagonists |
| US5482960A (en) * | 1994-11-14 | 1996-01-09 | Warner-Lambert Company | Nonpeptide endothelin antagonists |
| US5684032A (en) * | 1994-12-13 | 1997-11-04 | Smithkline Beecham Corporation | Compounds |
| EP1021181A4 (en) * | 1996-03-28 | 2002-06-26 | Smithkline Beecham Corp | INDOLCARBOXYLIC ACIDS AS CHEMOKIN INHIBITORS |
| US6184235B1 (en) * | 1996-08-14 | 2001-02-06 | Warner-Lambert Company | 2-phenyl benzimidazole derivatives as MCP-1 antagonists |
| GB9716657D0 (en) * | 1997-08-07 | 1997-10-15 | Zeneca Ltd | Chemical compounds |
| GB9716656D0 (en) * | 1997-08-07 | 1997-10-15 | Zeneca Ltd | Chemical compounds |
| GB9803228D0 (en) * | 1998-02-17 | 1998-04-08 | Zeneca Ltd | Chemical compounds |
| GB9803226D0 (en) * | 1998-02-17 | 1998-04-08 | Zeneca Ltd | Chemical compounds |
| GB9902461D0 (en) * | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
-
2000
- 2000-01-13 GB GBGB0000626.2A patent/GB0000626D0/en not_active Ceased
-
2001
- 2001-01-11 EE EEP200200394A patent/EE200200394A/xx unknown
- 2001-01-11 BR BR0107404-0A patent/BR0107404A/pt not_active IP Right Cessation
- 2001-01-11 JP JP2001551848A patent/JP2003519683A/ja active Pending
- 2001-01-11 AU AU25324/01A patent/AU780992B2/en not_active Ceased
- 2001-01-11 US US10/169,717 patent/US20030144339A1/en not_active Abandoned
- 2001-01-11 EP EP01900494A patent/EP1252142A1/en not_active Withdrawn
- 2001-01-11 IL IL15027201A patent/IL150272A0/xx unknown
- 2001-01-11 NZ NZ519312A patent/NZ519312A/en unknown
- 2001-01-11 CN CN01803645A patent/CN1395565A/zh active Pending
- 2001-01-11 RU RU2002121636/04A patent/RU2002121636A/ru not_active Application Discontinuation
- 2001-01-11 WO PCT/GB2001/000069 patent/WO2001051466A1/en not_active Application Discontinuation
- 2001-01-11 PL PL01356031A patent/PL356031A1/pl not_active Application Discontinuation
- 2001-01-11 SK SK1007-2002A patent/SK10072002A3/sk unknown
- 2001-01-11 HU HU0300694A patent/HUP0300694A3/hu unknown
- 2001-01-11 KR KR1020027009021A patent/KR20020064375A/ko not_active Application Discontinuation
- 2001-01-11 CA CA002393592A patent/CA2393592A1/en not_active Abandoned
- 2001-01-11 MX MXPA02006611A patent/MXPA02006611A/es unknown
- 2001-01-12 AR ARP010100144A patent/AR026839A1/es not_active Application Discontinuation
- 2001-01-15 CO CO01002379A patent/CO5271703A1/es not_active Application Discontinuation
-
2002
- 2002-05-30 ZA ZA200204354A patent/ZA200204354B/en unknown
- 2002-06-19 IS IS6429A patent/IS6429A/is unknown
- 2002-07-02 BG BG106894A patent/BG106894A/bg unknown
- 2002-07-12 NO NO20023380A patent/NO20023380L/no not_active Application Discontinuation
-
2003
- 2003-03-06 HK HK03101662.2A patent/HK1049486A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL150272A0 (en) | 2002-12-01 |
| IS6429A (is) | 2002-06-19 |
| HUP0300694A3 (en) | 2005-08-29 |
| CA2393592A1 (en) | 2001-07-19 |
| EP1252142A1 (en) | 2002-10-30 |
| SK10072002A3 (sk) | 2003-06-03 |
| BG106894A (bg) | 2003-04-30 |
| AU2532401A (en) | 2001-07-24 |
| US20030144339A1 (en) | 2003-07-31 |
| KR20020064375A (ko) | 2002-08-07 |
| GB0000626D0 (en) | 2000-03-01 |
| BR0107404A (pt) | 2002-10-08 |
| AR026839A1 (es) | 2003-02-26 |
| NO20023380L (no) | 2002-09-03 |
| EE200200394A (et) | 2003-12-15 |
| HK1049486A1 (zh) | 2003-05-16 |
| WO2001051466A1 (en) | 2001-07-19 |
| AU780992B2 (en) | 2005-04-28 |
| CO5271703A1 (es) | 2003-04-30 |
| HUP0300694A2 (hu) | 2003-07-28 |
| NZ519312A (en) | 2004-04-30 |
| MXPA02006611A (es) | 2002-09-30 |
| JP2003519683A (ja) | 2003-06-24 |
| NO20023380D0 (no) | 2002-07-12 |
| RU2002121636A (ru) | 2004-01-10 |
| ZA200204354B (en) | 2003-09-01 |
| CN1395565A (zh) | 2003-02-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1076459A1 (en) | 4-Phenyl-pyridine derivatives as neurokinin-1 receptor antagonists | |
| PL365377A1 (pl) | Pochodne amidów jako antagoniści receptora NMDA | |
| PL350184A1 (en) | Indole derivatives and their use as mcp-1 antagonists | |
| SI1224175T1 (en) | Benzodiazepine derivatives as metabotropic glutamate receptor antagonists | |
| PL357418A1 (pl) | Pochodne benzodiazepiny | |
| HRP20030031A2 (en) | 4-phenyl-pyridine derivatives as neurokinin-1 receptor antagonists | |
| PL356990A1 (pl) | Pochodne izoksazolokarboksyamidu | |
| IL152700A0 (en) | Substituted 1-aminoalkyl-lactams and their use as muscarinc receptor antagonists | |
| PL358584A1 (pl) | Pochodne cykloheksyloaminowe jako selektywni antagoniści podtypów receptora NMDA | |
| AU3166401A (en) | Indol-3-yl derivatives | |
| HUP0202142A2 (en) | Macrophage scavenger receptor antagonists | |
| EP1248607A4 (en) | UROTENSIN II RECEPTOR ANTAGONISTS | |
| IL144299A0 (en) | N-triazolymethyl-piperazine derivatives as neurokinin receptor antagonists | |
| EP1296958A4 (en) | ANTIAGONISTS OF NMDA NR2B RECEPTORS OF IMINOPYRIMIDINE | |
| IL150272A0 (en) | Indole derivatives as mcp-1 receptor antagonists | |
| PL350536A1 (en) | Biphenyl derivatives as antagonists of the neurokinine-1 receptor | |
| GB0028104D0 (en) | Bombesin receptor antagonists | |
| EP1351687A4 (en) | UROTENSIN II RECEPTOR ANTAGONISTS | |
| HK1047750A1 (zh) | 趨化因子受體拮抗劑 | |
| GB0028146D0 (en) | Bombesin receptor antagonists | |
| HK1043988A1 (zh) | 作為黃體酮拮抗劑的二氫吲衍生物 | |
| GB0107914D0 (en) | 7tm receptor hlwar77 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |