PL352374A1 - Inhibitors of integrine o v beta 6 - Google Patents

Inhibitors of integrine o v beta 6

Info

Publication number
PL352374A1
PL352374A1 PL00352374A PL35237400A PL352374A1 PL 352374 A1 PL352374 A1 PL 352374A1 PL 00352374 A PL00352374 A PL 00352374A PL 35237400 A PL35237400 A PL 35237400A PL 352374 A1 PL352374 A1 PL 352374A1
Authority
PL
Poland
Prior art keywords
integrine
inhibitors
beta
Prior art date
Application number
PL00352374A
Inventor
Alfred Jonczyk
Beate Diefenbach
Ulrich Groth
Gunther Zischinsky
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of PL352374A1 publication Critical patent/PL352374A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
PL00352374A 1999-06-26 2000-06-13 Inhibitors of integrine o v beta 6 PL352374A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19929410A DE19929410A1 (en) 1999-06-26 1999-06-26 New octapepide compounds as alpha v beta 6 integrin inhibitors useful for treating and diagnosing heart disease, tumors, osteoporosis, fibrosis, inflammation, infection and psoriasis
PCT/EP2000/005404 WO2001000660A1 (en) 1999-06-26 2000-06-13 INHIBITORS OF THE INTEGRIN αvβ¿6?

Publications (1)

Publication Number Publication Date
PL352374A1 true PL352374A1 (en) 2003-08-25

Family

ID=7912712

Family Applications (1)

Application Number Title Priority Date Filing Date
PL00352374A PL352374A1 (en) 1999-06-26 2000-06-13 Inhibitors of integrine o v beta 6

Country Status (17)

Country Link
EP (1) EP1189930A1 (en)
JP (1) JP2003503422A (en)
KR (1) KR20020015704A (en)
CN (1) CN1358195A (en)
AR (1) AR024472A1 (en)
AU (1) AU771099B2 (en)
BR (1) BR0011954A (en)
CA (1) CA2377224A1 (en)
CZ (1) CZ20014484A3 (en)
DE (1) DE19929410A1 (en)
HU (1) HUP0201729A3 (en)
MX (1) MXPA01013247A (en)
NO (1) NO20016341L (en)
PL (1) PL352374A1 (en)
SK (1) SK18722001A3 (en)
WO (1) WO2001000660A1 (en)
ZA (1) ZA200200673B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6972296B2 (en) 1999-05-07 2005-12-06 Encysive Pharmaceuticals Inc. Carboxylic acid derivatives that inhibit the binding of integrins to their receptors
JP2007523835A (en) 2003-02-06 2007-08-23 メルク　パテント　ゲゼルシャフト　ミット　ベシュレンクテル　ハフトング Peptidesulfonamide
GB0520068D0 (en) * 2005-10-03 2005-11-09 Cancer Res Technology av peptide ligand
ES2746925T3 (en) 2006-08-03 2020-03-09 Medimmune Ltd Antibodies Directed Towards alfaVbeta6 and Use of Them
ES2906109T3 (en) 2016-11-01 2022-04-13 Arrowhead Pharmaceuticals Inc Alpha-v beta-6 integrin ligands and uses thereof
EP3703700A4 (en) 2017-11-01 2021-08-04 Arrowhead Pharmaceuticals, Inc. Integrin ligands and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2103139A1 (en) * 1991-05-14 1992-11-15 George A. Heavner Peptide inhibitors of inflammation
ATE511850T1 (en) * 1997-08-08 2011-06-15 Univ California TREATMENT OF BLADDER FIBROSIS WITH ANTIBODIES TO ALPHA-V BETA-6 INTEGRIN
CZ20012212A3 (en) * 1998-12-19 2001-09-12 Merck Patent Gmbh Peptidic compound, use thereof and pharmaceutical preparation in which the compound is comprised

Also Published As

Publication number Publication date
NO20016341D0 (en) 2001-12-21
BR0011954A (en) 2002-05-07
EP1189930A1 (en) 2002-03-27
CN1358195A (en) 2002-07-10
CA2377224A1 (en) 2001-01-04
MXPA01013247A (en) 2002-07-02
CZ20014484A3 (en) 2002-04-17
KR20020015704A (en) 2002-02-28
SK18722001A3 (en) 2002-05-09
AU6263000A (en) 2001-01-31
DE19929410A1 (en) 2000-12-28
HUP0201729A2 (en) 2002-08-28
HUP0201729A3 (en) 2005-01-28
AU771099B2 (en) 2004-03-11
WO2001000660A1 (en) 2001-01-04
AR024472A1 (en) 2002-10-02
NO20016341L (en) 2002-02-25
ZA200200673B (en) 2003-04-24
JP2003503422A (en) 2003-01-28

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