HK1042695A1 - Prothease inhibitors - Google Patents

Prothease inhibitors

Info

Publication number
HK1042695A1
HK1042695A1 HK02102419.7A HK02102419A HK1042695A1 HK 1042695 A1 HK1042695 A1 HK 1042695A1 HK 02102419 A HK02102419 A HK 02102419A HK 1042695 A1 HK1042695 A1 HK 1042695A1
Authority
HK
Hong Kong
Prior art keywords
prothease
inhibitors
prothease inhibitors
Prior art date
Application number
HK02102419.7A
Other languages
Chinese (zh)
Inventor
Wells Marquis Robert Jr
Frank Veber Daniel
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of HK1042695A1 publication Critical patent/HK1042695A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/16—Eight-membered rings
    • C07D313/18—Eight-membered rings not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HK02102419.7A 1999-02-19 2002-03-28 Prothease inhibitors HK1042695A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12069999P 1999-02-19 1999-02-19
PCT/US2000/004133 WO2000049011A1 (en) 1999-02-19 2000-02-17 Prothease inhibitors

Publications (1)

Publication Number Publication Date
HK1042695A1 true HK1042695A1 (en) 2002-08-23

Family

ID=22392011

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02102419.7A HK1042695A1 (en) 1999-02-19 2002-03-28 Prothease inhibitors

Country Status (8)

Country Link
EP (1) EP1153022A4 (en)
JP (1) JP2002537297A (en)
AU (1) AU3235100A (en)
CO (1) CO5271679A1 (en)
DZ (1) DZ3083A1 (en)
HK (1) HK1042695A1 (en)
PE (1) PE20001486A1 (en)
WO (1) WO2000049011A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7168084B1 (en) 1992-12-09 2007-01-23 Sedna Patent Services, Llc Method and apparatus for targeting virtual objects
US20030144175A1 (en) 1998-12-23 2003-07-31 Smithkline Beecham Corporation Protease inhibitors
WO2001034599A1 (en) 1999-11-10 2001-05-17 Smithkline Beecham Corporation Protease inhibitors
EP1229914A4 (en) 1999-11-10 2004-06-23 Smithkline Beecham Corp Protease inhibitors
WO2001034600A1 (en) 1999-11-10 2001-05-17 Smithkline Beecham Corporation Protease inhibitors
NZ520588A (en) 2000-03-21 2004-06-25 Smithkline Beecham Corp Protease inhibitors
JP2004513942A (en) * 2000-11-17 2004-05-13 メディヴァー　ユーケイ　リミテッド Cysteine protease inhibitor
JP2004520439A (en) * 2000-11-17 2004-07-08 メディヴィル・アクチボラグ Cysteine protease inhibitor
DE502004001386D1 (en) * 2003-05-27 2006-10-19 Merck Patent Gmbh Pyranderivative with exocyclic double bond
ATE340836T1 (en) 2003-05-27 2006-10-15 Merck Patent Gmbh PYRAND DERIVATIVES
EP1757284A1 (en) * 2005-08-25 2007-02-28 Santhera Pharmaceuticals (Schweiz) AG Use of N-(dibenz(b,f)oxepin-10ylmethyl)-N-methyl-N-prop-2-ynylamine (omigapil) for the prophylaxis and/or treatment of muscular dystrophy

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5021432A (en) * 1988-04-26 1991-06-04 Yoshitomi Pharmaceutical Industries, Ltd. Benzopyran compound and its pharmaceutical use
CA2157412A1 (en) * 1993-03-03 1994-09-15 Julia Marie Heerding Balanoids
US5612370A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phenylglycine and phenylalaninen amido benzopyran derivatives
AR013079A1 (en) * 1997-05-06 2000-12-13 Smithkline Beecham Corp SUBSTITUTED DERIVATIVES OF TETRAHIDROFURANO-3-ONAS, TETRAHIDROPIRANO-3- ONAS AND TETRAHIDROTIOFEN-3-ONAS, A PROCEDURE FOR THE PREPARATION OF A PHARMACEUTICAL COMPOSITION OF A MEDICINAL PRODUCT USEFUL AS INTERMEDIATE PROTEIN INHIBITORS

Also Published As

Publication number Publication date
JP2002537297A (en) 2002-11-05
EP1153022A1 (en) 2001-11-14
CO5271679A1 (en) 2003-04-30
AU3235100A (en) 2000-09-04
WO2000049011A1 (en) 2000-08-24
DZ3083A1 (en) 2004-06-02
EP1153022A4 (en) 2002-03-27
PE20001486A1 (en) 2001-02-08

Similar Documents

Publication Publication Date Title
GB9900416D0 (en) Inhibitors
IL146518A0 (en) Metalloprotease inhibitors
EG23979A (en) Renin inhibitors
IL148820A0 (en) Fab i inhibitors
IL145085A0 (en) Dihetero-substituted metalloprotease inhibitors
EP1153022A4 (en) Prothease inhibitors
EP1235577A4 (en) Protease inhibitors
GB9924522D0 (en) Enzyme inhibitors
EP1232155A4 (en) Protease inhibitors
EP1229912A4 (en) Protease inhibitors
EP1231921A4 (en) Protease inhibitors
EP1229915A4 (en) Protease inhibitors
EP1229914A4 (en) Protease inhibitors
EP1161237A4 (en) Protease inhibitors
EP1233771A4 (en) Protease inhibitors
EP1173429A4 (en) Protease inhibitors
EP1229911A4 (en) Protease inhibitors
EP1351930A4 (en) Protease inhibitors
GB2389113B (en) B-secretase inhibitor
EP1231923A4 (en) Protease inhibitors
EP1232154A4 (en) Protease inhibitors
EP1231922A4 (en) Protease inhibitors
EP1189618A4 (en) Thrombin inhibitors
GB9929341D0 (en) Inhibitors
GB9929340D0 (en) Inhibitors