PL3481839T3 - Sposób oczyszczania metylokobalaminy - Google Patents
Sposób oczyszczania metylokobalaminyInfo
- Publication number
- PL3481839T3 PL3481839T3 PL17714232.0T PL17714232T PL3481839T3 PL 3481839 T3 PL3481839 T3 PL 3481839T3 PL 17714232 T PL17714232 T PL 17714232T PL 3481839 T3 PL3481839 T3 PL 3481839T3
- Authority
- PL
- Poland
- Prior art keywords
- methylcobalamin
- purification
- Prior art date
Links
- 238000000034 method Methods 0.000 title 1
- JEWJRMKHSMTXPP-BYFNXCQMSA-M methylcobalamin Chemical compound C[Co+]N([C@]1([H])[C@H](CC(N)=O)[C@]\2(CCC(=O)NC[C@H](C)OP(O)(=O)OC3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)C)C/2=C(C)\C([C@H](C/2(C)C)CCC(N)=O)=N\C\2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O JEWJRMKHSMTXPP-BYFNXCQMSA-M 0.000 title 1
- 235000007672 methylcobalamin Nutrition 0.000 title 1
- 239000011585 methylcobalamin Substances 0.000 title 1
- 238000000746 purification Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
- C07H1/06—Separation; Purification
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16178560 | 2016-07-08 | ||
| PCT/EP2017/057506 WO2018007035A1 (en) | 2016-07-08 | 2017-03-30 | Process for the purification of methylcobalamin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3481839T3 true PL3481839T3 (pl) | 2023-10-02 |
Family
ID=56497551
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL17714232.0T PL3481839T3 (pl) | 2016-07-08 | 2017-03-30 | Sposób oczyszczania metylokobalaminy |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11059851B2 (pl) |
| EP (1) | EP3481839B1 (pl) |
| JP (1) | JP6867409B2 (pl) |
| ES (1) | ES2952837T3 (pl) |
| HU (1) | HUE063127T2 (pl) |
| PL (1) | PL3481839T3 (pl) |
| WO (1) | WO2018007035A1 (pl) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108546278A (zh) * | 2018-03-17 | 2018-09-18 | 山东辰龙药业有限公司 | 甲钴胺的精制方法 |
| CN108948116A (zh) * | 2018-08-30 | 2018-12-07 | 上海应用技术大学 | 一种甲钴胺的绿色合成工艺 |
| AU2021369843A1 (en) * | 2020-10-27 | 2023-05-18 | Commonwealth Scientific And Industrial Research Organisation | Process for removing cyanide from a cyanide-bearing aqueous fluid |
| CN113959805B (zh) * | 2021-10-25 | 2024-06-21 | 淄博高新技术产业开发区生物医药研究院 | 甲钴胺原料药中氯化钴杂质的分析检测方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4538059B1 (pl) * | 1967-07-27 | 1970-12-02 | ||
| BE759614A (fr) * | 1969-12-01 | 1971-06-01 | Glaxo Lab Ltd | Elimination d'ions cyanure de solutions de corrinoides |
| GB1306958A (en) * | 1970-09-30 | 1973-02-14 | Pierrel Spa | Process for the preparation of substituted cobamides |
| US3928320A (en) * | 1971-11-10 | 1975-12-23 | Jean Boige | Process for the preparation of methylcobalamine |
| BE789252A (fr) * | 1971-11-10 | 1973-03-26 | Boige Jean | Procede de fabrication de la methylcobalamine |
| NO742545L (pl) * | 1973-08-08 | 1975-03-10 | Opochimie L | |
| JPS6256491A (ja) * | 1985-09-06 | 1987-03-12 | Eisai Co Ltd | 高純度メチルコバラミンの製造法 |
| JP3948958B2 (ja) * | 1999-12-09 | 2007-07-25 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | メチルコバラミンの製造法 |
| WO2002098896A1 (en) * | 2001-06-05 | 2002-12-12 | Eisai Co., Ltd. | Process for producing methylcobalamin |
-
2017
- 2017-03-30 HU HUE17714232A patent/HUE063127T2/hu unknown
- 2017-03-30 ES ES17714232T patent/ES2952837T3/es active Active
- 2017-03-30 JP JP2018558675A patent/JP6867409B2/ja active Active
- 2017-03-30 WO PCT/EP2017/057506 patent/WO2018007035A1/en not_active Ceased
- 2017-03-30 EP EP17714232.0A patent/EP3481839B1/en active Active
- 2017-03-30 US US16/311,091 patent/US11059851B2/en active Active
- 2017-03-30 PL PL17714232.0T patent/PL3481839T3/pl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2019521962A (ja) | 2019-08-08 |
| ES2952837T3 (es) | 2023-11-06 |
| WO2018007035A1 (en) | 2018-01-11 |
| EP3481839C0 (en) | 2023-06-07 |
| EP3481839A1 (en) | 2019-05-15 |
| HUE063127T2 (hu) | 2024-01-28 |
| JP6867409B2 (ja) | 2021-04-28 |
| US11059851B2 (en) | 2021-07-13 |
| EP3481839B1 (en) | 2023-06-07 |
| US20200308217A1 (en) | 2020-10-01 |
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