PL3458448T3 - Inhibitory fasn do zastosowania w leczeniu niealkoholowego stłuszczeniowego zapalenia wątroby - Google Patents
Inhibitory fasn do zastosowania w leczeniu niealkoholowego stłuszczeniowego zapalenia wątrobyInfo
- Publication number
- PL3458448T3 PL3458448T3 PL17790287T PL17790287T PL3458448T3 PL 3458448 T3 PL3458448 T3 PL 3458448T3 PL 17790287 T PL17790287 T PL 17790287T PL 17790287 T PL17790287 T PL 17790287T PL 3458448 T3 PL3458448 T3 PL 3458448T3
- Authority
- PL
- Poland
- Prior art keywords
- alcoholic steatohepatitis
- treating non
- fasn inhibitors
- fasn
- inhibitors
- Prior art date
Links
- 101150003888 FASN gene Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 208000008338 non-alcoholic fatty liver disease Diseases 0.000 title 1
- 206010053219 non-alcoholic steatohepatitis Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662327167P | 2016-04-25 | 2016-04-25 | |
| PCT/US2017/029469 WO2017189613A1 (en) | 2016-04-25 | 2017-04-25 | Methods of using fasn inhibitors |
| EP17790287.1A EP3458448B1 (en) | 2016-04-25 | 2017-04-25 | Fasn inhibitors for use in treating non-alcoholic steatohepatitis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3458448T3 true PL3458448T3 (pl) | 2021-12-06 |
Family
ID=60157111
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL17790287T PL3458448T3 (pl) | 2016-04-25 | 2017-04-25 | Inhibitory fasn do zastosowania w leczeniu niealkoholowego stłuszczeniowego zapalenia wątroby |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20170312273A1 (pl) |
| EP (1) | EP3458448B1 (pl) |
| DK (1) | DK3458448T3 (pl) |
| ES (1) | ES2886935T3 (pl) |
| MA (1) | MA45047A (pl) |
| PL (1) | PL3458448T3 (pl) |
| PT (1) | PT3458448T (pl) |
| TW (1) | TW201737943A (pl) |
| WO (1) | WO2017189613A1 (pl) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2014249003A1 (en) | 2013-03-13 | 2015-10-15 | Forma Therapeutics, Inc. | Novel compounds and compositions for inhibition of FASN |
| JP7300394B2 (ja) | 2017-01-17 | 2023-06-29 | ヘパリジェニックス ゲーエムベーハー | 肝再生の促進又は肝細胞死の低減もしくは予防のためのプロテインキナーゼ阻害 |
| TWI767148B (zh) | 2018-10-10 | 2022-06-11 | 美商弗瑪治療公司 | 抑制脂肪酸合成酶(fasn) |
| WO2020092376A1 (en) * | 2018-10-29 | 2020-05-07 | Forma Therapeutics, Inc. | Treating non-alcoholic steatohepatitis (nash) |
| US10793554B2 (en) * | 2018-10-29 | 2020-10-06 | Forma Therapeutics, Inc. | Solid forms of 4-(2-fluoro-4-(1-methyl-1H-benzo[d]imidazol-5-yl)benzoyl)piperazin-1-yl)(1-hydroxycyclopropyl)methanone |
| CN113265468B (zh) * | 2021-07-21 | 2021-10-12 | 北京大学第三医院（北京大学第三临床医学院） | 一种与宫颈癌诊断、治疗和预后相关的miRNA |
| WO2023093700A1 (zh) * | 2021-11-29 | 2023-06-01 | 中国海洋大学 | 咪唑并噻唑衍生物及其制备方法与应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4911920A (en) | 1986-07-30 | 1990-03-27 | Alcon Laboratories, Inc. | Sustained release, comfort formulation for glaucoma therapy |
| FR2588189B1 (fr) | 1985-10-03 | 1988-12-02 | Merck Sharp & Dohme | Composition pharmaceutique de type a transition de phase liquide-gel |
| EP0495421B1 (en) | 1991-01-15 | 1996-08-21 | Alcon Laboratories, Inc. | Use of carrageenans in topical ophthalmic compositions |
| US5212162A (en) | 1991-03-27 | 1993-05-18 | Alcon Laboratories, Inc. | Use of combinations gelling polysaccharides and finely divided drug carrier substrates in topical ophthalmic compositions |
| US6309853B1 (en) | 1994-08-17 | 2001-10-30 | The Rockfeller University | Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof |
| MX2009009189A (es) * | 2007-02-27 | 2009-11-05 | Fasgen Diagnostics Llc | Sintasa de acido graso en la enfermedad de higado. |
| AU2014249003A1 (en) | 2013-03-13 | 2015-10-15 | Forma Therapeutics, Inc. | Novel compounds and compositions for inhibition of FASN |
| JP6412553B2 (ja) | 2013-03-21 | 2018-10-24 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ | Ｆａｓｎ阻害剤としてのピペラジン誘導体 |
| CA2932396C (en) | 2013-12-03 | 2022-03-29 | Janssen Pharmaceutica Nv | Benzamide derivative useful as fasn inhibitors for the treatment of cancer |
| CA2934257C (en) | 2013-12-17 | 2022-06-07 | Janssen Pharmaceutica Nv | Imidazolin-5-one derivative useful as fasn inhibitors for the treatment of cancer |
-
2017
- 2017-04-25 ES ES17790287T patent/ES2886935T3/es active Active
- 2017-04-25 US US15/497,125 patent/US20170312273A1/en not_active Abandoned
- 2017-04-25 PT PT177902871T patent/PT3458448T/pt unknown
- 2017-04-25 TW TW106113737A patent/TW201737943A/zh unknown
- 2017-04-25 MA MA045047A patent/MA45047A/fr unknown
- 2017-04-25 WO PCT/US2017/029469 patent/WO2017189613A1/en active Application Filing
- 2017-04-25 EP EP17790287.1A patent/EP3458448B1/en active Active
- 2017-04-25 DK DK17790287.1T patent/DK3458448T3/da active
- 2017-04-25 PL PL17790287T patent/PL3458448T3/pl unknown
-
2019
- 2019-08-20 US US16/545,339 patent/US20190374536A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ES2886935T3 (es) | 2021-12-21 |
| WO2017189613A1 (en) | 2017-11-02 |
| TW201737943A (zh) | 2017-11-01 |
| EP3458448A4 (en) | 2019-04-17 |
| PT3458448T (pt) | 2021-09-10 |
| EP3458448B1 (en) | 2021-06-23 |
| US20190374536A1 (en) | 2019-12-12 |
| EP3458448A1 (en) | 2019-03-27 |
| DK3458448T3 (da) | 2021-08-23 |
| MA45047A (fr) | 2019-03-27 |
| US20170312273A1 (en) | 2017-11-02 |
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