PL345562A1 - Arylpiperazine derivatives useful as uroselective alpha1-adrenoceptor blockers - Google Patents

Arylpiperazine derivatives useful as uroselective alpha1-adrenoceptor blockers

Info

Publication number
PL345562A1
PL345562A1 PL99345562A PL34556299A PL345562A1 PL 345562 A1 PL345562 A1 PL 345562A1 PL 99345562 A PL99345562 A PL 99345562A PL 34556299 A PL34556299 A PL 34556299A PL 345562 A1 PL345562 A1 PL 345562A1
Authority
PL
Poland
Prior art keywords
uroselective
alpha1
derivatives useful
adrenoceptor blockers
arylpiperazine derivatives
Prior art date
Application number
PL99345562A
Other languages
English (en)
Inventor
Nitya Anand
Neelima Sinha
Sanjay Jain
Anita Mehta
Anil Kumar Saxena
Jang Bahadur Gupta
Original Assignee
Ranbaxy Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/120,265 external-priority patent/US6083950A/en
Priority claimed from PCT/IB1999/000140 external-priority patent/WO2000005206A1/en
Application filed by Ranbaxy Lab Ltd filed Critical Ranbaxy Lab Ltd
Publication of PL345562A1 publication Critical patent/PL345562A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36Oxygen or sulfur atoms
    • C07D207/402,5-Pyrrolidine-diones
    • C07D207/4042,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36Oxygen or sulfur atoms
    • C07D207/402,5-Pyrrolidine-diones
    • C07D207/4042,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
    • C07D207/408Radicals containing only hydrogen and carbon atoms attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/86Oxygen atoms
    • C07D211/88Oxygen atoms attached in positions 2 and 6, e.g. glutarimide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL99345562A 1998-07-21 1999-07-16 Arylpiperazine derivatives useful as uroselective alpha1-adrenoceptor blockers PL345562A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/120,265 US6083950A (en) 1997-11-13 1998-07-21 1-(4-arylpiperazin-1-yl)-ω-[n-(α,ω-dicarboximido)]-alka nes useful as uro-selective α1-adrenoceptor blockers
PCT/IB1999/000140 WO2000005206A1 (en) 1998-07-21 1999-01-26 Arylpiperazine derivatives useful as uro-selective alpha-1-adrenoceptor blockers
PCT/IB1999/001296 WO2000005205A1 (en) 1998-07-21 1999-07-16 Arylpiperazine derivatives useful as uroselective alpha1-adrenoceptor blockers

Publications (1)

Publication Number Publication Date
PL345562A1 true PL345562A1 (en) 2001-12-17

Family

ID=26318738

Family Applications (1)

Application Number Title Priority Date Filing Date
PL99345562A PL345562A1 (en) 1998-07-21 1999-07-16 Arylpiperazine derivatives useful as uroselective alpha1-adrenoceptor blockers

Country Status (10)

Country Link
EP (1) EP1097134A1 (xx)
AU (1) AU763541B2 (xx)
BR (1) BR9912318A (xx)
CA (1) CA2338317A1 (xx)
HU (1) HUP0102980A3 (xx)
MX (1) MXPA01000637A (xx)
NZ (1) NZ509388A (xx)
PL (1) PL345562A1 (xx)
SK (1) SK932001A3 (xx)
WO (1) WO2000005205A1 (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ592340A (en) 2001-03-27 2012-12-21 Elenore S Bogoch A method for making a virus vaccine compising Replikin peptides
WO2005113498A1 (en) * 2004-05-19 2005-12-01 Ranbaxy Laboratories Limited Adrenergic receptor antagonists
WO2005118537A2 (en) * 2004-05-31 2005-12-15 Ranbaxy Laboratories Limited Arylpiperazine derivatives as adrenergic receptor antagonists

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE788280A (fr) * 1971-09-04 1973-02-28 Pfizer Nouvelles 1-(3-trifluoro-methyl-phenyl)-4-((amido cyclique)- alkyl) piperazines et composition pharmaceutique les contenant
DE2727469A1 (de) * 1977-06-18 1978-12-21 Hoechst Ag Neue hexahydropyrimidine, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten
JPS57197265A (en) * 1981-05-29 1982-12-03 Eisai Co Ltd Carboxylic acid imide derivative, its preparation and medicament containing the same
US4452798A (en) * 1982-06-22 1984-06-05 Warner-Lambert Company 1-Substituted phenyl-4-alkyl hydantoin piperazine compounds as antihypertensive agents
US4675403A (en) * 1985-10-16 1987-06-23 American Home Products Corporation 3-Aminoalkyl derivatives of 5,5-disubstituted hydantoins with psychotropic activity
ES2094690B1 (es) * 1994-11-22 1997-08-01 Univ Madrid Complutense Nuevos derivados de imida-piperazinas.
ATE201016T1 (de) * 1995-06-09 2001-05-15 Hoffmann La Roche Pyrimidindion-, pyrimidintrion-, triazindion- derivate als alpha-1-adrenergische rezeptorantagonisten

Also Published As

Publication number Publication date
BR9912318A (pt) 2001-05-02
SK932001A3 (en) 2001-08-06
WO2000005205A1 (en) 2000-02-03
HUP0102980A3 (en) 2003-02-28
NZ509388A (en) 2003-12-19
CA2338317A1 (en) 2000-02-03
MXPA01000637A (es) 2002-04-08
HUP0102980A2 (hu) 2001-12-28
AU763541B2 (en) 2003-07-24
EP1097134A1 (en) 2001-05-09
AU4641099A (en) 2000-02-14

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Legal Events

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REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)