PL3445351T3 - Acetyloleucyna lub jej farmaceutycznie dopuszczalna sól do poprawy mobilności - Google Patents
Acetyloleucyna lub jej farmaceutycznie dopuszczalna sól do poprawy mobilnościInfo
- Publication number
- PL3445351T3 PL3445351T3 PL17719692.0T PL17719692T PL3445351T3 PL 3445351 T3 PL3445351 T3 PL 3445351T3 PL 17719692 T PL17719692 T PL 17719692T PL 3445351 T3 PL3445351 T3 PL 3445351T3
- Authority
- PL
- Poland
- Prior art keywords
- leucine
- acetyl
- pharmaceutically acceptable
- acceptable salt
- improved mobility
- Prior art date
Links
- WXNXCEHXYPACJF-ZETCQYMHSA-N N-acetyl-L-leucine Chemical compound CC(C)C[C@@H](C(O)=O)NC(C)=O WXNXCEHXYPACJF-ZETCQYMHSA-N 0.000 title 1
- 229960000669 acetylleucine Drugs 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB201606834 | 2016-04-19 | ||
| PCT/GB2017/051090 WO2017182802A1 (en) | 2016-04-19 | 2017-04-19 | Acetyl-leucine or a pharmaceutically acceptable salt thereof for improved mobility and cognitive function |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3445351T3 true PL3445351T3 (pl) | 2025-01-07 |
Family
ID=58633040
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL17719692.0T PL3445351T3 (pl) | 2016-04-19 | 2017-04-19 | Acetyloleucyna lub jej farmaceutycznie dopuszczalna sól do poprawy mobilności |
Country Status (27)
| Country | Link |
|---|---|
| US (4) | US10905670B2 (pl) |
| EP (2) | EP4501406A3 (pl) |
| JP (3) | JP7387264B2 (pl) |
| KR (4) | KR102413754B1 (pl) |
| CN (2) | CN109069463B (pl) |
| AU (2) | AU2017252507B2 (pl) |
| BR (1) | BR112018071547A2 (pl) |
| CA (1) | CA3021155A1 (pl) |
| DK (1) | DK3445351T3 (pl) |
| ES (1) | ES2994242T3 (pl) |
| FI (1) | FI3445351T3 (pl) |
| HR (1) | HRP20241552T1 (pl) |
| HU (1) | HUE069219T2 (pl) |
| IL (3) | IL310508A (pl) |
| LT (1) | LT3445351T (pl) |
| MD (1) | MD3445351T2 (pl) |
| MX (2) | MX388461B (pl) |
| NZ (1) | NZ747307A (pl) |
| PL (1) | PL3445351T3 (pl) |
| PT (1) | PT3445351T (pl) |
| RS (1) | RS66142B1 (pl) |
| RU (1) | RU2745912C2 (pl) |
| SG (2) | SG11201809031XA (pl) |
| SI (1) | SI3445351T1 (pl) |
| SM (1) | SMT202400459T1 (pl) |
| WO (1) | WO2017182802A1 (pl) |
| ZA (1) | ZA201806849B (pl) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL310508A (en) * | 2016-04-19 | 2024-03-01 | Intrabio Ltd | Acetyl-leucine or its acceptable pharmacy salt for improved mobility and cognitive function |
| CN109789114A (zh) | 2016-08-11 | 2019-05-21 | 内在生物技术有限公司 | 神经退行性疾病的治疗剂 |
| GB201709459D0 (en) | 2017-06-14 | 2017-07-26 | Intrabio Ltd | Treatment for migraine |
| US12145899B2 (en) | 2018-12-06 | 2024-11-19 | Intrabio Ltd. | Deuterated analogs of acetyl-leucine |
| KR20210135272A (ko) * | 2019-03-02 | 2021-11-12 | 인트라바이오 리미티드 | 질환을 치료하기 위한 류신, 아세틸 류신, 및 관련된 유사체 |
| US12171852B1 (en) | 2023-07-18 | 2024-12-24 | Sytheon Ltd | Composition and methods for regulating melanogenesis |
| WO2025166100A1 (en) | 2024-02-02 | 2025-08-07 | SynGAP Research Fund | Compositions and methods for treating neurodevelopmental disorders |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060063827A1 (en) * | 2004-09-23 | 2006-03-23 | Yu Ruey J | Systemic administration of therapeutic amino acids and N-acetylamino acids |
| US20070190070A1 (en) * | 2004-09-03 | 2007-08-16 | Zeldis Jerome B | Methods of using and compositions comprising selective cytokine inhibitory drugs for the treatment and management of disorders of the central nervous system |
| FR2883180B1 (fr) * | 2005-03-18 | 2007-05-25 | Pierre Fabre Medicament Sa | Utilisation de l'acetyl-leucine pour la preparation d'un medicament destine au traitement de troubles de l'equilibre |
| FR2905600B1 (fr) * | 2006-09-13 | 2010-01-15 | Pf Medicament | Traitement des vertiges par l'acetyl-l-leucine. |
| US20080097606A1 (en) * | 2006-10-19 | 2008-04-24 | Cragg Andrew H | Knee joint prosthesis and hyaluronate compositions for treatment of osteoarthritis |
| WO2008134844A1 (en) * | 2007-05-08 | 2008-11-13 | Multi Formulations Ltd. | Branched-chain amino acid composition for improving skeletal muscle protein metabolism |
| WO2011025518A1 (en) * | 2009-08-27 | 2011-03-03 | Albert Einstein College Of Medicine Of Yeshiva University | Cognitive function training to improve motor ability |
| TN2010000251A1 (fr) * | 2010-06-03 | 2011-11-11 | Rekik Raouf | N-acetyl-dl-leucine medicament neuro et retino protecteur |
| WO2012060844A1 (en) * | 2010-11-05 | 2012-05-10 | Biotie Therapies, Inc | A2a antagonists as cognition and motor function enhancers |
| TN2010000566A1 (en) * | 2010-12-03 | 2012-05-24 | Rekik Raouf | Folic acid - ramipril combination : cell protective neuroprotective and retinoprotective ophtalmologic drugs |
| IL310508A (en) * | 2016-04-19 | 2024-03-01 | Intrabio Ltd | Acetyl-leucine or its acceptable pharmacy salt for improved mobility and cognitive function |
| WO2019079536A1 (en) * | 2017-10-18 | 2019-04-25 | Intrabio Ltd | THERAPEUTIC AGENTS FOR IMPROVED MOBILITY AND COGNITIVE FUNCTION AND FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES AND LYSOSOMAL STORAGE DISORDERS |
-
2017
- 2017-04-19 IL IL310508A patent/IL310508A/en unknown
- 2017-04-19 LT LTEPPCT/GB2017/051090T patent/LT3445351T/lt unknown
- 2017-04-19 AU AU2017252507A patent/AU2017252507B2/en active Active
- 2017-04-19 IL IL293266A patent/IL293266B2/en unknown
- 2017-04-19 HR HRP20241552TT patent/HRP20241552T1/hr unknown
- 2017-04-19 PT PT177196920T patent/PT3445351T/pt unknown
- 2017-04-19 KR KR1020227008412A patent/KR102413754B1/ko active Active
- 2017-04-19 MX MX2018012739A patent/MX388461B/es unknown
- 2017-04-19 SM SM20240459T patent/SMT202400459T1/it unknown
- 2017-04-19 IL IL262379A patent/IL262379B/en unknown
- 2017-04-19 MD MDE20190248T patent/MD3445351T2/ro unknown
- 2017-04-19 EP EP24205813.9A patent/EP4501406A3/en active Pending
- 2017-04-19 RS RS20241222A patent/RS66142B1/sr unknown
- 2017-04-19 KR KR1020227021015A patent/KR102632670B1/ko active Active
- 2017-04-19 JP JP2018555644A patent/JP7387264B2/ja active Active
- 2017-04-19 DK DK17719692.0T patent/DK3445351T3/da active
- 2017-04-19 FI FIEP17719692.0T patent/FI3445351T3/fi active
- 2017-04-19 SI SI201731566T patent/SI3445351T1/sl unknown
- 2017-04-19 KR KR1020247003393A patent/KR102791288B1/ko active Active
- 2017-04-19 PL PL17719692.0T patent/PL3445351T3/pl unknown
- 2017-04-19 CN CN201780029480.6A patent/CN109069463B/zh active Active
- 2017-04-19 SG SG11201809031XA patent/SG11201809031XA/en unknown
- 2017-04-19 US US16/093,780 patent/US10905670B2/en active Active
- 2017-04-19 HU HUE17719692A patent/HUE069219T2/hu unknown
- 2017-04-19 RU RU2018140131A patent/RU2745912C2/ru active
- 2017-04-19 CN CN202410876111.2A patent/CN118593463A/zh active Pending
- 2017-04-19 SG SG10202106190RA patent/SG10202106190RA/en unknown
- 2017-04-19 NZ NZ747307A patent/NZ747307A/en unknown
- 2017-04-19 WO PCT/GB2017/051090 patent/WO2017182802A1/en not_active Ceased
- 2017-04-19 EP EP17719692.0A patent/EP3445351B1/en active Active
- 2017-04-19 CA CA3021155A patent/CA3021155A1/en active Pending
- 2017-04-19 BR BR112018071547-6A patent/BR112018071547A2/pt not_active Application Discontinuation
- 2017-04-19 ES ES17719692T patent/ES2994242T3/es active Active
- 2017-04-19 KR KR1020187032983A patent/KR20180134398A/ko not_active Ceased
-
2018
- 2018-10-15 ZA ZA2018/06849A patent/ZA201806849B/en unknown
- 2018-10-18 MX MX2021014844A patent/MX2021014844A/es unknown
-
2020
- 2020-12-22 US US17/247,757 patent/US11998518B2/en active Active
-
2021
- 2021-11-12 JP JP2021185130A patent/JP7506046B2/ja active Active
-
2022
- 2022-10-17 AU AU2022256077A patent/AU2022256077A1/en not_active Abandoned
-
2023
- 2023-07-10 US US18/349,221 patent/US12329733B2/en active Active
-
2024
- 2024-06-13 JP JP2024096260A patent/JP2024123087A/ja active Pending
-
2025
- 2025-05-13 US US19/206,473 patent/US20250332133A1/en active Pending
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