PL3394097T3 - Przeciwciała przeciwko immunokompleksom zawierającym hepatotoksyny będące cyklicznymi peptydami cyjanobakterii - Google Patents

Przeciwciała przeciwko immunokompleksom zawierającym hepatotoksyny będące cyklicznymi peptydami cyjanobakterii

Info

Publication number
PL3394097T3
PL3394097T3 PL16826085.9T PL16826085T PL3394097T3 PL 3394097 T3 PL3394097 T3 PL 3394097T3 PL 16826085 T PL16826085 T PL 16826085T PL 3394097 T3 PL3394097 T3 PL 3394097T3
Authority
PL
Poland
Prior art keywords
hepatotoxins
immunocomplexes
antibodies against
cyclic peptide
cyanobacterial
Prior art date
Application number
PL16826085.9T
Other languages
English (en)
Inventor
Markus VEHNIÄINEN
Urpo Lamminmäki
Sultana AKTER
Original Assignee
Turun Yliopisto
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Turun Yliopisto filed Critical Turun Yliopisto
Publication of PL3394097T3 publication Critical patent/PL3394097T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/005—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL16826085.9T 2015-12-21 2016-12-21 Przeciwciała przeciwko immunokompleksom zawierającym hepatotoksyny będące cyklicznymi peptydami cyjanobakterii PL3394097T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20155980 2015-12-21
PCT/FI2016/050911 WO2017109290A1 (en) 2015-12-21 2016-12-21 Antibodies against immunocomplexes comprising cyanobacterial cyclic peptide hepatotoxins

Publications (1)

Publication Number Publication Date
PL3394097T3 true PL3394097T3 (pl) 2026-05-25

Family

ID=57796377

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16826085.9T PL3394097T3 (pl) 2015-12-21 2016-12-21 Przeciwciała przeciwko immunokompleksom zawierającym hepatotoksyny będące cyklicznymi peptydami cyjanobakterii

Country Status (8)

Country Link
US (1) US10808024B2 (pl)
EP (1) EP3394097B1 (pl)
CN (1) CN108779169B (pl)
AU (1) AU2016378819C1 (pl)
CA (1) CA3047691C (pl)
ES (1) ES3061719T3 (pl)
PL (1) PL3394097T3 (pl)
WO (1) WO2017109290A1 (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109896638B (zh) * 2019-03-22 2021-11-02 湖州师范学院 微囊藻毒素降解酶在降解节球藻毒素中的应用
CN111499737B (zh) * 2020-01-21 2022-02-11 华南农业大学 一种特异性检测藻毒素类物质的纳米抗体及酶联免疫分析方法
WO2022164818A2 (en) * 2021-01-26 2022-08-04 The Regents Of The University Of California Prevention of posterior capsular opacification (pco) with integrin avb8 blocking antibody
JP2024505001A (ja) * 2021-01-26 2024-02-02 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア Avb8インテグリンに関連する疾患を処置および予防するための組成物および方法
WO2023081266A2 (en) * 2021-11-03 2023-05-11 University Of Pittsburgh – Of The Commonwealth System Of Higher Education Molecules that bind to protogenin (prtg) polypeptides
CN115508555B (zh) * 2022-05-07 2025-08-22 珠海圣美生物诊断技术有限公司 循环pd-l1阳性细胞检测的试剂盒及方法
CN117783508A (zh) * 2023-12-25 2024-03-29 杭州安旭生物科技股份有限公司 一种筛选生物素标记工艺的试剂盒及应用
WO2025202545A1 (en) * 2024-03-27 2025-10-02 Turun Yliopisto Immunocomplex antibodies and non-competitive immunoassay for the detection of testosterone
CN118754991B (zh) * 2024-08-20 2025-05-27 海南医科大学(海南省医学科学院) 一种快速检测腺苷脱氨酶2的试剂盒及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000055917A (ja) 1998-08-05 2000-02-25 Mitsubishi Kagaku Bio-Clinical Laboratories Inc 抗抗原−抗体複合体抗体を用いた検出または測定方法
US6967240B1 (en) 1999-09-06 2005-11-22 Daniel R. Dietrich Congener independent detection of microcystin and nodularin congeners
FI20022048A0 (fi) * 2002-11-18 2002-11-18 Valtion Teknillinen Ei-kompetetiivinen immunomääritys pienille analyyteille
MX2008010612A (es) * 2006-02-15 2009-03-20 Ramot At Tel Aviv University Bacteriofago filamentoso que exhibe proteina a como aglutinante de anticuerpos e inmunocomplejos para el suministro hacia el cerebro.
EP2759551B1 (en) 2011-09-21 2019-05-22 Fujirebio Inc. Antibodies binding to an affinity complex comprising 25oh vitamin d2 or d3 and an antibody thereto

Also Published As

Publication number Publication date
ES3061719T3 (en) 2026-04-07
CN108779169A (zh) 2018-11-09
AU2016378819B2 (en) 2021-12-09
EP3394097B1 (en) 2025-11-26
BR112018012679A2 (pt) 2018-12-04
AU2016378819A1 (en) 2018-07-26
CN108779169B (zh) 2022-06-07
CA3047691A1 (en) 2017-06-29
EP3394097A1 (en) 2018-10-31
NZ744212A (en) 2024-07-26
WO2017109290A1 (en) 2017-06-29
US20190010218A1 (en) 2019-01-10
CA3047691C (en) 2022-12-06
AU2016378819C1 (en) 2022-06-16
EP3394097C0 (en) 2025-11-26
US10808024B2 (en) 2020-10-20