PL3350145T3 - Środki wiążące dna z ogonem wiążącym mniejszą bruzdę - Google Patents
Środki wiążące dna z ogonem wiążącym mniejszą bruzdęInfo
- Publication number
- PL3350145T3 PL3350145T3 PL16847389T PL16847389T PL3350145T3 PL 3350145 T3 PL3350145 T3 PL 3350145T3 PL 16847389 T PL16847389 T PL 16847389T PL 16847389 T PL16847389 T PL 16847389T PL 3350145 T3 PL3350145 T3 PL 3350145T3
- Authority
- PL
- Poland
- Prior art keywords
- tail
- minor groove
- binding
- dna binding
- binding agents
- Prior art date
Links
- 239000011230 binding agent Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C13/00—Cyclic hydrocarbons containing rings other than, or in addition to, six-membered aromatic rings
- C07C13/28—Polycyclic hydrocarbons or acyclic hydrocarbon derivatives thereof
- C07C13/32—Polycyclic hydrocarbons or acyclic hydrocarbon derivatives thereof with condensed rings
- C07C13/62—Polycyclic hydrocarbons or acyclic hydrocarbon derivatives thereof with condensed rings with more than three condensed rings
- C07C13/66—Polycyclic hydrocarbons or acyclic hydrocarbon derivatives thereof with condensed rings with more than three condensed rings the condensed ring system contains only four rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/14—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/244—Anthraquinone radicals, e.g. sennosides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562219380P | 2015-09-16 | 2015-09-16 | |
| PCT/US2016/052144 WO2017049091A1 (en) | 2015-09-16 | 2016-09-16 | Dna binding agents with a minor groove binding tail |
| EP16847389.0A EP3350145B1 (en) | 2015-09-16 | 2016-09-16 | Dna binding agents with a minor groove binding tail |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3350145T3 true PL3350145T3 (pl) | 2021-05-04 |
Family
ID=58289623
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL16847389T PL3350145T3 (pl) | 2015-09-16 | 2016-09-16 | Środki wiążące dna z ogonem wiążącym mniejszą bruzdę |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10358439B2 (pl) |
| EP (1) | EP3350145B1 (pl) |
| JP (1) | JP6966428B2 (pl) |
| CN (1) | CN108368006B (pl) |
| AU (1) | AU2016323777B2 (pl) |
| PL (1) | PL3350145T3 (pl) |
| WO (1) | WO2017049091A1 (pl) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023091993A1 (en) * | 2021-11-17 | 2023-05-25 | Board Of Regents, The University Of Texas System | Water-soluble salts of dna binding agents |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4288608A (en) | 1978-06-01 | 1981-09-08 | Research Corporation | Synthesis of anthracyclines |
| US4196127A (en) * | 1978-06-01 | 1980-04-01 | Research Corporation | Anthracyclines |
| CA1174669A (en) * | 1980-07-18 | 1984-09-18 | Michael J. Broadhurst | Anthracycline glycosides |
| ZA814722B (en) * | 1980-07-18 | 1982-07-28 | Hoffmann La Roche | Novel anthracycline glycosides |
| WO1997034612A1 (en) * | 1996-03-22 | 1997-09-25 | Waldemar Priebe | Bis-anthracyclines with high activity against doxorubicin resistant tumors |
| GB9812937D0 (en) * | 1998-06-16 | 1998-08-12 | Btg Int Ltd | Compounds |
| EP1165578B1 (en) * | 1999-03-19 | 2012-02-22 | Waldemar Priebe | Methods and compositions for the manufacture of c-3' and c-4' anthracycline antibiotics |
| AU2003217782A1 (en) * | 2002-02-27 | 2003-09-09 | The Government Of The United States Of America, Representated By The Secretary, Deparment Of Health | Dna-binding polyamide drug conjugates |
| CN101284136A (zh) * | 2002-12-03 | 2008-10-15 | 布朗歇特洛克菲勒神经科学研究所 | 传输物质穿过血脑屏障的人工低密度脂蛋白载体 |
| SE0401066D0 (sv) * | 2004-04-22 | 2004-04-22 | Stefan Sjoeberg | Chemical Derivatives |
| PL380561A1 (pl) | 2006-09-05 | 2008-03-17 | Szeja Wiesław Prochem Szeja | Sposób otrzymywania pochodnych antracyklin |
| AU2010223045A1 (en) * | 2009-03-12 | 2011-11-03 | Luitpold Pharmaceuticals, Inc. | GABA-linked anthracycline-lipid conjugates |
-
2016
- 2016-09-16 WO PCT/US2016/052144 patent/WO2017049091A1/en not_active Ceased
- 2016-09-16 CN CN201680066385.9A patent/CN108368006B/zh active Active
- 2016-09-16 PL PL16847389T patent/PL3350145T3/pl unknown
- 2016-09-16 EP EP16847389.0A patent/EP3350145B1/en active Active
- 2016-09-16 JP JP2018513780A patent/JP6966428B2/ja active Active
- 2016-09-16 US US15/759,884 patent/US10358439B2/en active Active
- 2016-09-16 AU AU2016323777A patent/AU2016323777B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3350145B1 (en) | 2020-09-16 |
| CN108368006B (zh) | 2023-03-07 |
| JP2018527372A (ja) | 2018-09-20 |
| EP3350145A1 (en) | 2018-07-25 |
| AU2016323777B2 (en) | 2021-05-13 |
| AU2016323777A1 (en) | 2018-04-12 |
| US10358439B2 (en) | 2019-07-23 |
| CA2998867A1 (en) | 2017-03-23 |
| US20180251454A1 (en) | 2018-09-06 |
| EP3350145A4 (en) | 2019-03-27 |
| JP6966428B2 (ja) | 2021-11-17 |
| CN108368006A (zh) | 2018-08-03 |
| WO2017049091A1 (en) | 2017-03-23 |
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