PL3319941T3 - Dwuetapowy sposób wytwarzania 3-podstawionych fenyloalkiloamin - Google Patents
Dwuetapowy sposób wytwarzania 3-podstawionych fenyloalkiloaminInfo
- Publication number
- PL3319941T3 PL3319941T3 PL16824898T PL16824898T PL3319941T3 PL 3319941 T3 PL3319941 T3 PL 3319941T3 PL 16824898 T PL16824898 T PL 16824898T PL 16824898 T PL16824898 T PL 16824898T PL 3319941 T3 PL3319941 T3 PL 3319941T3
- Authority
- PL
- Poland
- Prior art keywords
- preparing
- step process
- substituted phenylalkylamines
- phenylalkylamines
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/69—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to carbon-to-carbon double or triple bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562190975P | 2015-07-10 | 2015-07-10 | |
EP16824898.7A EP3319941B1 (en) | 2015-07-10 | 2016-07-06 | A two-step process for preparing 3-substituted phenylalkylamines |
PCT/US2016/041027 WO2017011231A1 (en) | 2015-07-10 | 2016-07-06 | A two-step process for preparing 3-substituted phenylalkylamines |
Publications (1)
Publication Number | Publication Date |
---|---|
PL3319941T3 true PL3319941T3 (pl) | 2022-05-02 |
Family
ID=57730262
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL21216875.1T PL3995492T3 (pl) | 2015-07-10 | 2016-07-06 | Dwuetapowy sposób wytwarzania 3-podstawionych fenyloalkiloamin |
PL16824898T PL3319941T3 (pl) | 2015-07-10 | 2016-07-06 | Dwuetapowy sposób wytwarzania 3-podstawionych fenyloalkiloamin |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL21216875.1T PL3995492T3 (pl) | 2015-07-10 | 2016-07-06 | Dwuetapowy sposób wytwarzania 3-podstawionych fenyloalkiloamin |
Country Status (13)
Country | Link |
---|---|
US (1) | US9914695B2 (pl) |
EP (2) | EP3319941B1 (pl) |
JP (1) | JP6463854B2 (pl) |
AU (1) | AU2016292797B2 (pl) |
BR (1) | BR112018000036B1 (pl) |
CA (1) | CA2991421C (pl) |
DK (2) | DK3995492T3 (pl) |
ES (1) | ES2908442T3 (pl) |
HU (1) | HUE058824T2 (pl) |
MX (1) | MX370658B (pl) |
PL (2) | PL3995492T3 (pl) |
PT (2) | PT3319941T (pl) |
WO (1) | WO2017011231A1 (pl) |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2340812C2 (de) | 1973-08-11 | 1982-05-27 | Basf Ag, 6700 Ludwigshafen | Phenylpropanale sowie ein Verfahren zu deren Herstellung |
DE4426245A1 (de) | 1994-07-23 | 1996-02-22 | Gruenenthal Gmbh | 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung |
CA2285578A1 (en) | 1999-10-07 | 2001-04-07 | Innovations Foundation | Rhodium-catalyzed addition of alkenyl- and aryltrifluoroborates to aldehydes and enones |
US7399858B2 (en) | 2002-11-11 | 2008-07-15 | Mallinckrodt Inc. | Method for the catalytic production of hydrocodone, hydromorphone, and derivatives thereof |
US7321038B2 (en) | 2002-11-11 | 2008-01-22 | Mallinckrodt Inc. | Method for the catalytic production of hydrocodone and hydromorphone |
US7323565B2 (en) | 2002-11-11 | 2008-01-29 | Mallinckrodt Inc. | Method for the catalytic production of hydrocodone and hydromorphone |
DE10326097A1 (de) | 2003-06-06 | 2005-01-05 | Grünenthal GmbH | Verfahren zur Herstellung von Dimethyl-(3-aryl-butyl)-aminverbindungen |
DE10328316A1 (de) * | 2003-06-23 | 2005-01-20 | Grünenthal GmbH | Verfahren zur Herstellung von Dimethyl-(3-aryl-buthyl)-aminverbindungen als pharmazeutische Wirkstoffe |
TWI401237B (zh) | 2006-07-24 | 2013-07-11 | 3-〔(1r,2r)-3-(二甲基氨基)-1-乙基-2-甲基丙基〕酚之製備 | |
EA015003B1 (ru) * | 2006-07-24 | 2011-04-29 | Янссен Фармацевтика Нв | Получение (2r,3r)-3-(3-метоксифенил)-n,n,2-триметилпентанамина |
US7399859B1 (en) | 2007-02-06 | 2008-07-15 | Cody Laboratories Inc. | Method for catalytic preparation of hydromorphone and hydrocodone |
CN102002065B (zh) | 2009-09-02 | 2014-09-10 | 上海特化医药科技有限公司 | 他喷他多的制备方法及其中间体 |
WO2011080736A1 (en) | 2009-12-29 | 2011-07-07 | Mapi Pharma Hk Limited | Intermediate compounds and processes for the preparation of tapentadol and related compounds |
WO2011092719A2 (en) * | 2010-02-01 | 2011-08-04 | Ind-Swift Laboratories Limited | Process for the preparation of l-phenyl-3-dimethylaminopropane derivatives |
CA2790519A1 (en) | 2010-03-05 | 2011-09-09 | Actavis Group Ptc Ehf | Improved resolution methods for isolating desired enantiomers of tapentadol intermediates and use thereof for the preparation of tapentadol |
EP2582659B1 (en) * | 2010-06-15 | 2015-03-11 | Grünenthal GmbH | Process for the preparation of substituted 3-(1-amino-2-methylpentane-3-yl)phenyl compounds |
US8853456B2 (en) | 2010-08-16 | 2014-10-07 | Indoco Remedies Limited | Process for the preparation of tapentadol |
EP2619174A4 (en) | 2010-09-20 | 2014-05-14 | Ind Swift Lab Ltd | PROCESS FOR THE PREPARATION OF L-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVES |
EP2545028A4 (en) | 2011-01-27 | 2013-07-03 | Symed Labs Ltd | STEREOSPECIFIC SYNTHESIS OF (-) (2S, 3S) -1-DIMETHYLAMINO-3- (3-METHOXYPHENYL) -2-METHYLPENTAN-3-OLE |
US20130150622A1 (en) * | 2011-12-12 | 2013-06-13 | Boehringer Ingelheim International Gmbh | Stereoselective synthesis of tapentadol and its salts |
PT3166923T (pt) * | 2014-07-10 | 2023-06-02 | SpecGx LLC | Processo para preparar fenilalcanos substituídos |
-
2016
- 2016-07-06 ES ES16824898T patent/ES2908442T3/es active Active
- 2016-07-06 PT PT168248987T patent/PT3319941T/pt unknown
- 2016-07-06 PL PL21216875.1T patent/PL3995492T3/pl unknown
- 2016-07-06 HU HUE16824898A patent/HUE058824T2/hu unknown
- 2016-07-06 DK DK21216875.1T patent/DK3995492T3/da active
- 2016-07-06 CA CA2991421A patent/CA2991421C/en active Active
- 2016-07-06 BR BR112018000036-1A patent/BR112018000036B1/pt active IP Right Grant
- 2016-07-06 MX MX2017016624A patent/MX370658B/es active IP Right Grant
- 2016-07-06 WO PCT/US2016/041027 patent/WO2017011231A1/en active Application Filing
- 2016-07-06 DK DK16824898.7T patent/DK3319941T3/da active
- 2016-07-06 PT PT212168751T patent/PT3995492T/pt unknown
- 2016-07-06 US US15/202,670 patent/US9914695B2/en active Active
- 2016-07-06 EP EP16824898.7A patent/EP3319941B1/en active Active
- 2016-07-06 EP EP21216875.1A patent/EP3995492B1/en active Active
- 2016-07-06 AU AU2016292797A patent/AU2016292797B2/en active Active
- 2016-07-06 PL PL16824898T patent/PL3319941T3/pl unknown
- 2016-07-06 JP JP2017566102A patent/JP6463854B2/ja active Active
Also Published As
Publication number | Publication date |
---|---|
EP3995492B1 (en) | 2024-05-29 |
ES2908442T3 (es) | 2022-04-29 |
PL3995492T3 (pl) | 2024-09-23 |
JP6463854B2 (ja) | 2019-02-06 |
EP3319941A4 (en) | 2019-03-20 |
JP2018524322A (ja) | 2018-08-30 |
AU2016292797B2 (en) | 2018-05-31 |
PT3319941T (pt) | 2022-03-18 |
DK3319941T3 (da) | 2022-03-14 |
DK3995492T3 (da) | 2024-08-19 |
BR112018000036A2 (pt) | 2018-09-04 |
EP3319941B1 (en) | 2021-12-29 |
US20170008832A1 (en) | 2017-01-12 |
EP3319941A1 (en) | 2018-05-16 |
MX2017016624A (es) | 2018-11-09 |
MX370658B (es) | 2019-12-19 |
CA2991421A1 (en) | 2017-01-19 |
EP3995492A1 (en) | 2022-05-11 |
WO2017011231A1 (en) | 2017-01-19 |
PT3995492T (pt) | 2024-08-21 |
CA2991421C (en) | 2019-04-30 |
US9914695B2 (en) | 2018-03-13 |
AU2016292797A1 (en) | 2018-01-25 |
BR112018000036B1 (pt) | 2023-12-12 |
HUE058824T2 (hu) | 2022-09-28 |
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