PL3280402T3 - Związki tolanowe do wspomagania gojenia się ran - Google Patents

Związki tolanowe do wspomagania gojenia się ran

Info

Publication number
PL3280402T3
PL3280402T3 PL16777246.6T PL16777246T PL3280402T3 PL 3280402 T3 PL3280402 T3 PL 3280402T3 PL 16777246 T PL16777246 T PL 16777246T PL 3280402 T3 PL3280402 T3 PL 3280402T3
Authority
PL
Poland
Prior art keywords
wound healing
promoting wound
tolan compounds
tolan
compounds
Prior art date
Application number
PL16777246.6T
Other languages
English (en)
Inventor
Chun-Che Tsai
Karen M. Mcguire
James M. JAMISON
Jack L. Summers
Original Assignee
BioMendics, LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BioMendics, LLC filed Critical BioMendics, LLC
Publication of PL3280402T3 publication Critical patent/PL3280402T3/pl

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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2985807T3 (es) * 2015-04-08 2024-11-07 Biomendics Llc Compuestos de tolano para favorecer la cicatrización de heridas
WO2018081425A1 (en) * 2016-10-26 2018-05-03 Wake Forest University Health Sciences Hydrogen-bonding compounds, compositions comprising the same, and methods of preparing and using the same
CN107056854B (zh) * 2017-06-12 2018-11-09 江西师范大学 一种邻炔基酚醚类糖苷化给体及其制备方法和应用
CN111526873B (zh) 2017-07-27 2025-03-04 生物曼迪克斯有限责任公司 用于调节微生物定殖的经取代的二苯乙炔
US10758559B1 (en) 2017-09-01 2020-09-01 University Of Wyoming Targeting cathepsin K to facilitate wound healing
US11766467B2 (en) 2017-09-01 2023-09-26 University Of Wyoming Methods of treating wounds using cathepsin K inhibitors
US11629329B2 (en) 2017-10-11 2023-04-18 Wake Forest University Health Sciences Bioink compositions and methods of preparing and using the same
KR102233566B1 (ko) * 2018-05-04 2021-03-30 서울대학교산학협력단 스틸벤 유도체를 포함하는 만성 폐질환의 예방 또는 치료용 조성물
JOP20180129A1 (ar) * 2018-12-24 2020-06-24 Univ Of Petra تركيبة لتسريع التئام الجروح
KR20230051262A (ko) 2020-09-17 2023-04-17 가부시끼가이샤 레조낙 오토파지 활성화제
JPWO2022059776A1 (pl) 2020-09-17 2022-03-24
EP4215199A4 (en) 2020-09-17 2024-10-09 Resonac Corporation AUTOPHAGY ACTIVATOR
TW202228676A (zh) * 2020-09-17 2022-08-01 日商昭和電工股份有限公司 自噬活化劑
CN113105883B (zh) * 2021-03-17 2023-08-18 汕头大学 一种基于二苯乙炔和环糊精的超分子余辉发光复合物及制备与应用
WO2025143141A1 (ja) * 2023-12-26 2025-07-03 江崎グリコ株式会社 オートファジー活性化剤

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5498795A (en) * 1994-12-29 1996-03-12 Allergan, Inc. Acetylenes disubstituted with hydroxyaryl and aryl or heteroaryl groups having retinoid-like biological activity
DE19624155A1 (de) * 1996-06-18 1998-01-08 Hoechst Ag Substituierte Benzoesäurederivate, Verfahren zu ihrer Herstellung und die Anwendung der Verbindungen zur Behandlung von Krankheiten
US6008260A (en) 1998-01-09 1999-12-28 Pharmascience Cancer chemopreventative composition and method
US6197834B1 (en) 1998-09-01 2001-03-06 Northeastern Ohio Universities College Of Medicine Method of inhibiting formation of infectious herpes virus particles
US7321050B2 (en) 1999-12-06 2008-01-22 Welichem Biotech Inc. Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues
CA2423337A1 (en) * 2000-08-15 2002-02-21 Northeastern Ohio Universities College Of Medicine Methods for treating subjects infected with a herpes virus orneisseria gonorrheae
CA2529510A1 (en) 2003-07-01 2005-01-13 President And Fellows Of Harvard College Compositions for manipulating the lifespan and stress response of cells and organisms
US8017634B2 (en) 2003-12-29 2011-09-13 President And Fellows Of Harvard College Compositions for treating obesity and insulin resistance disorders
ITRM20050446A1 (it) 2005-08-19 2007-02-20 Tubilux Pharma S P A Uso di stilbeni idrossilati e glucosidati per la prevenzione ed il trattamento di patologie oculari.
US7678819B2 (en) 2006-12-07 2010-03-16 The Trustees Of The University Of Pennsylvania Acetylene derivatives and their use for binding and imaging amyloid plaques
US8716355B2 (en) * 2007-06-20 2014-05-06 Kent State University Hydroxylated tolans and related compounds in the treatment of a cancer
WO2008157745A1 (en) 2007-06-20 2008-12-24 Kent State University Ascorbate, vitamin k3 and hydroxytolans in the treatment of cancer
KR101196680B1 (ko) 2007-06-29 2012-11-06 어큐셀라 인코포레이티드 안과 질환 및 장애 치료용 알키닐 페닐 유도체 화합물
WO2009126700A1 (en) 2008-04-08 2009-10-15 Kent State University Hydroxylated tolans and related compounds as cosmetics or therapeutics for skin conditions
CN101991590B (zh) * 2009-08-17 2013-03-20 南京正大天晴制药有限公司 二苯乙烯苷药物组合物及其制备方法
WO2011042482A1 (en) * 2009-10-06 2011-04-14 Green Molecular Polyphenols for use in the treatment of cancer
CN103079557A (zh) * 2010-02-03 2013-05-01 微生物公司 作为抗菌剂用于包括细菌生物膜的治疗的生物医学用途以及其它用途的铋-硫醇
US20110256753A1 (en) 2010-04-16 2011-10-20 Amphenol Corporation Electronic assembly with keying and guidance features
DE112010005680T5 (de) 2010-06-24 2013-05-16 Livart Marine Industry Co., Ltd. Kupplungsstruktur für einen Yachtpier
US20120058088A1 (en) * 2010-06-28 2012-03-08 Resveratrol Partners, Llc Resveratrol-Containing Compositions And Methods Of Use
US20120070401A1 (en) * 2010-09-21 2012-03-22 Jinzhong Zhang Composition and Method for Promoting Wound Healing
US20130261077A1 (en) * 2012-03-07 2013-10-03 Vertex Pharmaceuticals Incorporated Mannose derivatives for treating bacterial infections
US20150272924A1 (en) * 2012-11-08 2015-10-01 Summa Health System Vitamin c, vitamin k, a polyphenol, and combinations thereof for wound healing
US8822382B2 (en) * 2013-05-05 2014-09-02 Nazir Mir Hydrocolloid systems for reducing loss of volatile active compounds from their liquid formulations for pre- and post harvest use on agricultural crops
US20160058712A1 (en) * 2014-08-29 2016-03-03 Muhammed Majeed 3-hydroxypterostilbene and therapeutic applications thereof
ES2985807T3 (es) * 2015-04-08 2024-11-07 Biomendics Llc Compuestos de tolano para favorecer la cicatrización de heridas

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