PL3261644T3 - Kompozycje i sposoby leczenia degradacji siatkówki - Google Patents

Kompozycje i sposoby leczenia degradacji siatkówki

Info

Publication number
PL3261644T3
PL3261644T3 PL16756477T PL16756477T PL3261644T3 PL 3261644 T3 PL3261644 T3 PL 3261644T3 PL 16756477 T PL16756477 T PL 16756477T PL 16756477 T PL16756477 T PL 16756477T PL 3261644 T3 PL3261644 T3 PL 3261644T3
Authority
PL
Poland
Prior art keywords
compositions
methods
treating retinal
retinal degradation
degradation
Prior art date
Application number
PL16756477T
Other languages
English (en)
Inventor
Jayakrishna Ambati
Benjamin Fowler
Kameshwari AMBATI
Original Assignee
University Of Kentucky Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Of Kentucky Research Foundation filed Critical University Of Kentucky Research Foundation
Publication of PL3261644T3 publication Critical patent/PL3261644T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D411/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D411/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D411/04Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL16756477T 2015-02-26 2016-02-26 Kompozycje i sposoby leczenia degradacji siatkówki PL3261644T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562121379P 2015-02-26 2015-02-26
US201562246455P 2015-10-26 2015-10-26
US201562247099P 2015-10-27 2015-10-27
PCT/US2016/019852 WO2016138425A1 (en) 2015-02-26 2016-02-26 Compositions and methods for treating retinal degradation
EP16756477.2A EP3261644B1 (en) 2015-02-26 2016-02-26 Compositions and methods for treating retinal degradation

Publications (1)

Publication Number Publication Date
PL3261644T3 true PL3261644T3 (pl) 2021-10-25

Family

ID=56789808

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16756477T PL3261644T3 (pl) 2015-02-26 2016-02-26 Kompozycje i sposoby leczenia degradacji siatkówki

Country Status (13)

Country Link
US (1) US10294220B2 (pl)
EP (3) EP3858826A1 (pl)
JP (1) JP6691922B2 (pl)
KR (2) KR102469789B1 (pl)
AU (3) AU2016225037B2 (pl)
CA (1) CA2976537C (pl)
DK (1) DK3261644T3 (pl)
ES (2) ES3010307T3 (pl)
FI (1) FI4215527T3 (pl)
HR (1) HRP20211050T1 (pl)
PL (1) PL3261644T3 (pl)
PT (2) PT4215527T (pl)
WO (1) WO2016138425A1 (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9326983B2 (en) 2013-08-01 2016-05-03 University Of Kentucky Research Foundation Compositions and methods for treating retinal degradation
FR3027804A1 (fr) * 2014-10-31 2016-05-06 Centre Nat Rech Scient Utilisation d'un inhibiteur de transcriptase inverse dans la prevention et le traitement des maladies degeneratives
US11219623B2 (en) 2015-02-26 2022-01-11 University Of Kentucky Research Foundation Inflammasome inhibition for the treatment of Parkinson's disease, Alzheimer's disease and multiple sclerosis
WO2019074884A2 (en) * 2017-10-10 2019-04-18 University Of Virginia Patent Foundation COMPOSITIONS AND METHODS FOR TREATMENT OF AGE-RELATED MACULAR DEGENERATION AND GEOGRAPHIC ATROPHY
EP3746057B1 (en) * 2018-01-31 2024-03-20 Olatec Therapeutics, Inc. Dapansutrile for preventing or treating alzheimer's disease
JP7402225B2 (ja) * 2018-05-11 2023-12-20 ロード アイランド ホスピタル ヌクレオシド系逆転写酵素阻害剤を用いて関節障害を処置するための組成物および方法
WO2020076960A1 (en) * 2018-10-09 2020-04-16 Jayakrishna Ambati Endogenous cytoplasmic alu complementary dna in age-related macular degeneration
AU2020211600A1 (en) * 2019-01-25 2021-07-22 Brown University Compositions and methods for treating, preventing or reversing age-associated inflammation and disorders
CA3149147A1 (en) * 2019-08-23 2021-03-04 Jayakrishna Ambati Ddx17 and nlrc4 targeting for inflammatory diseases
EP4114409A4 (en) * 2020-03-20 2024-08-07 University of Virginia Patent Foundation NRTIS, NRTI METABOLITES AND NRTI ANALOGUES FOR MACULAR DEGENERATION AND VIRAL INFECTIONS
AU2021303146A1 (en) * 2020-06-29 2023-02-02 Bacainn Biotherapeutics, Ltd. Probenecid compounds for the treatment of inflammasome-mediated lung disease
PE20250684A1 (es) 2022-03-15 2025-03-04 Rome Therapeutics Inc Compuestos y metodos para el tratamiento de enfermedades
WO2024123982A1 (en) * 2022-12-07 2024-06-13 University Of Virginia Patent Foundation Inflammasome and vegf inhibition for retinal vascular diseases

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63250396A (ja) * 1987-04-03 1988-10-18 Taiho Yakuhin Kogyo Kk 3′−アジド−3′−デオキシチミジン誘導体
ZA886890B (en) * 1987-10-09 1989-05-30 Hoffmann La Roche Novel dideoxycytidine derivatives
EP0355031A3 (de) * 1988-08-17 1990-12-27 MATTHES, Eckart, Dr. Substituierte Pyrimidinnucleoside, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Mittel
US6514979B1 (en) 1999-03-03 2003-02-04 University Of Maryland Biotechnology Institute Synergistic combinations of guanosine analog reverse transcriptase inhibitors and inosine monophosphate dehydrogenese inhibitors and uses therefor
MY164523A (en) * 2000-05-23 2017-12-29 Univ Degli Studi Cagliari Methods and compositions for treating hepatitis c virus
US20100226931A1 (en) * 2004-06-24 2010-09-09 Nicholas Valiante Compounds for immunopotentiation
WO2011153234A2 (en) 2010-06-01 2011-12-08 University Of Kentucky Research Foundation Methods of inhibiting alu rna and therapeutic uses thereof
EP2734240B1 (en) 2011-07-18 2018-03-21 University Of Kentucky Research Foundation Protection of cells from alu-rna-induced degenereation and inhibitors for protecting cells
US9707235B1 (en) 2012-01-13 2017-07-18 University Of Kentucky Research Foundation Protection of cells from degeneration and treatment of geographic atrophy
US10562974B2 (en) 2013-03-13 2020-02-18 University Of Kentucky Research Foundation Methods of administering IgG1 antibodies and methods of suppressing angiogenesis
US9326983B2 (en) 2013-08-01 2016-05-03 University Of Kentucky Research Foundation Compositions and methods for treating retinal degradation

Also Published As

Publication number Publication date
DK3261644T3 (da) 2021-06-28
EP3261644A1 (en) 2018-01-03
AU2021232790A1 (en) 2021-10-14
AU2016225037A1 (en) 2017-09-07
JP6691922B2 (ja) 2020-05-13
FI4215527T3 (fi) 2024-12-19
EP3858826A1 (en) 2021-08-04
AU2023229531A1 (en) 2023-09-28
CA2976537C (en) 2024-05-28
AU2023229531B2 (en) 2025-04-10
PT4215527T (pt) 2025-01-07
KR20210152580A (ko) 2021-12-15
WO2016138425A1 (en) 2016-09-01
AU2016225037B2 (en) 2021-06-17
EP4215527B1 (en) 2024-10-09
ES3010307T3 (en) 2025-04-02
US20180044327A1 (en) 2018-02-15
PT3261644T (pt) 2021-07-07
EP3261644B1 (en) 2021-06-02
KR20170123320A (ko) 2017-11-07
ES2879678T3 (es) 2021-11-22
EP4215527A1 (en) 2023-07-26
KR102469789B1 (ko) 2022-11-23
JP2018506558A (ja) 2018-03-08
HRP20211050T1 (hr) 2021-11-26
US10294220B2 (en) 2019-05-21
EP3261644A4 (en) 2018-07-25
AU2021232790B2 (en) 2023-10-05
CA2976537A1 (en) 2016-09-01

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