PL3261644T3 - Kompozycje i sposoby leczenia degradacji siatkówki - Google Patents

Kompozycje i sposoby leczenia degradacji siatkówki

Info

Publication number
PL3261644T3
PL3261644T3 PL16756477T PL16756477T PL3261644T3 PL 3261644 T3 PL3261644 T3 PL 3261644T3 PL 16756477 T PL16756477 T PL 16756477T PL 16756477 T PL16756477 T PL 16756477T PL 3261644 T3 PL3261644 T3 PL 3261644T3
Authority
PL
Poland
Prior art keywords
compositions
methods
treating retinal
retinal degradation
degradation
Prior art date
Application number
PL16756477T
Other languages
English (en)
Inventor
Jayakrishna Ambati
Benjamin Fowler
Kameshwari AMBATI
Original Assignee
University Of Kentucky Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Of Kentucky Research Foundation filed Critical University Of Kentucky Research Foundation
Publication of PL3261644T3 publication Critical patent/PL3261644T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D411/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL16756477T 2015-02-26 2016-02-26 Kompozycje i sposoby leczenia degradacji siatkówki PL3261644T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562121379P 2015-02-26 2015-02-26
US201562246455P 2015-10-26 2015-10-26
US201562247099P 2015-10-27 2015-10-27
PCT/US2016/019852 WO2016138425A1 (en) 2015-02-26 2016-02-26 Compositions and methods for treating retinal degradation
EP16756477.2A EP3261644B1 (en) 2015-02-26 2016-02-26 Compositions and methods for treating retinal degradation

Publications (1)

Publication Number Publication Date
PL3261644T3 true PL3261644T3 (pl) 2021-10-25

Family

ID=56789808

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16756477T PL3261644T3 (pl) 2015-02-26 2016-02-26 Kompozycje i sposoby leczenia degradacji siatkówki

Country Status (13)

Country Link
US (1) US10294220B2 (pl)
EP (3) EP3858826A1 (pl)
JP (1) JP6691922B2 (pl)
KR (2) KR102469789B1 (pl)
AU (3) AU2016225037B2 (pl)
CA (1) CA2976537C (pl)
DK (1) DK3261644T3 (pl)
ES (2) ES3010307T3 (pl)
FI (1) FI4215527T3 (pl)
HR (1) HRP20211050T1 (pl)
PL (1) PL3261644T3 (pl)
PT (2) PT4215527T (pl)
WO (1) WO2016138425A1 (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9326983B2 (en) 2013-08-01 2016-05-03 University Of Kentucky Research Foundation Compositions and methods for treating retinal degradation
FR3027804A1 (fr) * 2014-10-31 2016-05-06 Centre Nat Rech Scient Utilisation d'un inhibiteur de transcriptase inverse dans la prevention et le traitement des maladies degeneratives
US11219623B2 (en) 2015-02-26 2022-01-11 University Of Kentucky Research Foundation Inflammasome inhibition for the treatment of Parkinson's disease, Alzheimer's disease and multiple sclerosis
EP3672579A4 (en) * 2017-10-10 2021-06-23 University of Virginia Patent Foundation COMPOSITIONS AND METHODS OF TREATMENT OF AGE-RELATED MACULAR DEGENERATION AND GEOGRAPHICAL ATROPHY
CA3087865A1 (en) * 2018-01-31 2019-08-08 Olatec Therapeutics Llc Method for preventing or treating alzheimer's disease
WO2019217973A1 (en) * 2018-05-11 2019-11-14 Rhode Island Hospital Compositions and methods for treating articulating joint disorders with nucleoside reverse transcriptase inhibitors
EP3863714A4 (en) * 2018-10-09 2022-07-20 University of Virginia Patent Foundation ENDOGENOUS CYTOPLASMATIC ALU-COMPLEMENTARY DNA IN AGE-RELATED MACULAR DEGENERATION
MX2021008751A (es) 2019-01-25 2021-11-12 Univ Brown Composiciones y metodos para tratar, prevenir o revertir la inflamacion y los trastornos asociados a la edad.
WO2021041317A1 (en) * 2019-08-23 2021-03-04 University Of Virginia Patent Foundation Ddx17 and nlrc4 targeting for inflammatory diseases
US20230172962A1 (en) * 2020-03-20 2023-06-08 University Of Virginia Patent Foundation Nrtis, nrti metabolites, and nrti analogs for macular degeneration and viral infections
WO2022005881A1 (en) * 2020-06-29 2022-01-06 Bacainn Biotherapeutics, Inc. Probenecid compounds for the treatment of inflammasome-mediated lung disease
EP4493573A1 (en) 2022-03-15 2025-01-22 Rome Therapeutics, Inc. Compounds and methods for treating disease
WO2024123982A1 (en) * 2022-12-07 2024-06-13 University Of Virginia Patent Foundation Inflammasome and vegf inhibition for retinal vascular diseases

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63250396A (ja) * 1987-04-03 1988-10-18 Taiho Yakuhin Kogyo Kk 3′−アジド−3′−デオキシチミジン誘導体
ZA886890B (en) * 1987-10-09 1989-05-30 Hoffmann La Roche Novel dideoxycytidine derivatives
EP0355031A3 (de) * 1988-08-17 1990-12-27 MATTHES, Eckart, Dr. Substituierte Pyrimidinnucleoside, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Mittel
US6514979B1 (en) 1999-03-03 2003-02-04 University Of Maryland Biotechnology Institute Synergistic combinations of guanosine analog reverse transcriptase inhibitors and inosine monophosphate dehydrogenese inhibitors and uses therefor
PY0111577A (es) * 2000-05-23 2017-01-02 Idenix Cayman Ltd Métodos y composiciones para el tratamiento del virus de la hepatitis c
US20100226931A1 (en) * 2004-06-24 2010-09-09 Nicholas Valiante Compounds for immunopotentiation
WO2011153234A2 (en) 2010-06-01 2011-12-08 University Of Kentucky Research Foundation Methods of inhibiting alu rna and therapeutic uses thereof
ES2907620T3 (es) 2011-07-18 2022-04-25 Univ Kentucky Res Found Protección de células de la degeneración inducida por ARN Alu e inhibidores para proteger células
US9707235B1 (en) 2012-01-13 2017-07-18 University Of Kentucky Research Foundation Protection of cells from degeneration and treatment of geographic atrophy
US10562974B2 (en) 2013-03-13 2020-02-18 University Of Kentucky Research Foundation Methods of administering IgG1 antibodies and methods of suppressing angiogenesis
US9326983B2 (en) * 2013-08-01 2016-05-03 University Of Kentucky Research Foundation Compositions and methods for treating retinal degradation

Also Published As

Publication number Publication date
AU2021232790B2 (en) 2023-10-05
HRP20211050T1 (hr) 2021-11-26
JP2018506558A (ja) 2018-03-08
PT4215527T (pt) 2025-01-07
AU2016225037A1 (en) 2017-09-07
WO2016138425A1 (en) 2016-09-01
EP3261644B1 (en) 2021-06-02
EP3261644A4 (en) 2018-07-25
EP3858826A1 (en) 2021-08-04
CA2976537A1 (en) 2016-09-01
EP4215527A1 (en) 2023-07-26
ES3010307T3 (en) 2025-04-02
AU2021232790A1 (en) 2021-10-14
EP4215527B1 (en) 2024-10-09
US10294220B2 (en) 2019-05-21
FI4215527T3 (fi) 2024-12-19
KR102469789B1 (ko) 2022-11-23
CA2976537C (en) 2024-05-28
KR20210152580A (ko) 2021-12-15
PT3261644T (pt) 2021-07-07
AU2023229531A1 (en) 2023-09-28
EP3261644A1 (en) 2018-01-03
JP6691922B2 (ja) 2020-05-13
KR20170123320A (ko) 2017-11-07
AU2023229531B2 (en) 2025-04-10
ES2879678T3 (es) 2021-11-22
DK3261644T3 (da) 2021-06-28
US20180044327A1 (en) 2018-02-15
AU2016225037B2 (en) 2021-06-17

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