PL3158055T3 - Ulepszone wytwarzanie rekombinowanego czynnika von Willebranda w bioreaktorze - Google Patents

Ulepszone wytwarzanie rekombinowanego czynnika von Willebranda w bioreaktorze

Info

Publication number
PL3158055T3
PL3158055T3 PL15806732T PL15806732T PL3158055T3 PL 3158055 T3 PL3158055 T3 PL 3158055T3 PL 15806732 T PL15806732 T PL 15806732T PL 15806732 T PL15806732 T PL 15806732T PL 3158055 T3 PL3158055 T3 PL 3158055T3
Authority
PL
Poland
Prior art keywords
bioreactor
improved production
von willebrand
willebrand factor
recombinant von
Prior art date
Application number
PL15806732T
Other languages
English (en)
Inventor
Stefan DEBUS
Holger Lind
Original Assignee
Csl Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Csl Limited filed Critical Csl Limited
Publication of PL3158055T3 publication Critical patent/PL3158055T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/755Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL15806732T 2014-06-13 2015-04-14 Ulepszone wytwarzanie rekombinowanego czynnika von Willebranda w bioreaktorze PL3158055T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14172338 2014-06-13
EP15806732.2A EP3158055B1 (en) 2014-06-13 2015-04-14 Improved production of recombinant von willebrand factor in a bioreactor
PCT/AU2015/050170 WO2015188224A1 (en) 2014-06-13 2015-04-14 Improved production of recombinant von willebrand factor in a bioreactor

Publications (1)

Publication Number Publication Date
PL3158055T3 true PL3158055T3 (pl) 2020-03-31

Family

ID=50942583

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15806732T PL3158055T3 (pl) 2014-06-13 2015-04-14 Ulepszone wytwarzanie rekombinowanego czynnika von Willebranda w bioreaktorze

Country Status (8)

Country Link
US (1) US10829539B2 (pl)
EP (1) EP3158055B1 (pl)
CN (1) CN106414719B (pl)
AU (1) AU2015274238B2 (pl)
DK (1) DK3158055T3 (pl)
ES (1) ES2751607T3 (pl)
PL (1) PL3158055T3 (pl)
WO (1) WO2015188224A1 (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017146646A1 (en) * 2016-02-22 2017-08-31 Agency For Science, Technology And Research Cell culture medium
AU2018321131B2 (en) 2017-08-23 2024-06-13 Csl Behring Gmbh Method for virus filtration of von Willebrand Factor

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751180A (en) 1985-03-28 1988-06-14 Chiron Corporation Expression using fused genes providing for protein product
US4935233A (en) 1985-12-02 1990-06-19 G. D. Searle And Company Covalently linked polypeptide cell modulators
DE4435392B4 (de) 1994-10-04 2008-02-07 Immuno Ag Verfahren zur Trennung von vWF in hochmolekularen vWF und niedermolekularen vWF
AT405403B (de) 1997-02-27 1999-08-25 Immuno Ag Reinigung von von willebrand-faktor durch kationenaustauscherchromatographie
WO2005024044A2 (en) 2003-09-05 2005-03-17 Gtc Biotherapeutics, Inc. Method for the production of fusion proteins in transgenic mammal milk
WO2005035748A1 (en) 2003-10-10 2005-04-21 Novo Nordisk Health Care Ag Method for large-scale production of a polypeptide in eukaryote cells and a culture vessel suitable therefor
DK1835938T3 (da) 2004-12-27 2013-11-04 Baxter Int Polymer-von Willebrand-faktor-konjugater
DK2634242T3 (en) 2006-07-14 2017-05-22 Patheon Holdings I B V IMPROVED PROCEDURE FOR CULTURING CELLS
EP2014760A1 (en) * 2007-06-13 2009-01-14 CMC Biopharmaceuticals A/S A method for producing a biopolymer (e.g. polypeptide) in a continuous fermentation process
TW201731488A (zh) * 2007-12-28 2017-09-16 巴克斯歐塔公司 重組vwf調配物
DK2865760T3 (en) 2008-06-24 2018-01-15 Csl Behring Gmbh Factor VIII, Von Willebrand Factor or complexes thereof with extended in vivo half-life
TWI469992B (zh) * 2008-08-28 2015-01-21 Baxter Int 濃縮剪切靈敏生物聚合物的方法
HRP20130414T1 (en) 2008-10-21 2013-06-30 Baxter International Inc. Lyophilized recombinant vwf formulations
US8580554B2 (en) * 2009-07-31 2013-11-12 Baxter International Inc. Method of producing a polypeptide or virus of interest in a continuous cell culture
WO2011022657A1 (en) 2009-08-20 2011-02-24 Baxter International Inc. Purification of vwf for increased removal of non-lipid enveloped viruses
PL3626736T3 (pl) * 2010-07-08 2025-10-13 Takeda Pharmaceutical Company Limited Sposób wytwarzania rekombinowanego vwf o dużej masie cząsteczkowej w hodowli komórkowej

Also Published As

Publication number Publication date
CN106414719A (zh) 2017-02-15
AU2015274238A1 (en) 2017-02-02
WO2015188224A1 (en) 2015-12-17
US10829539B2 (en) 2020-11-10
AU2015274238B2 (en) 2020-11-05
EP3158055A4 (en) 2017-12-20
EP3158055B1 (en) 2019-09-11
EP3158055A1 (en) 2017-04-26
ES2751607T3 (es) 2020-04-01
US20170129938A1 (en) 2017-05-11
WO2015188224A9 (en) 2016-08-25
DK3158055T3 (da) 2019-10-14
CN106414719B (zh) 2020-02-14

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