PL312426A1 - Bicyclic tetrahydropyrazolepyridines - Google Patents
Bicyclic tetrahydropyrazolepyridinesInfo
- Publication number
- PL312426A1 PL312426A1 PL94312426A PL31242694A PL312426A1 PL 312426 A1 PL312426 A1 PL 312426A1 PL 94312426 A PL94312426 A PL 94312426A PL 31242694 A PL31242694 A PL 31242694A PL 312426 A1 PL312426 A1 PL 312426A1
- Authority
- PL
- Poland
- Prior art keywords
- tetrahydropyrazolepyridines
- bicyclic
- bicyclic tetrahydropyrazolepyridines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8829293A | 1993-07-06 | 1993-07-06 | |
| PCT/IB1994/000156 WO1995001980A1 (en) | 1993-07-06 | 1994-06-16 | Bicyclic tetrahydro pyrazolopyridines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL312426A1 true PL312426A1 (en) | 1996-04-29 |
Family
ID=22210524
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL94312426A PL312426A1 (en) | 1993-07-06 | 1994-06-16 | Bicyclic tetrahydropyrazolepyridines |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0707585A1 (en) |
| JP (1) | JP2944048B2 (en) |
| KR (1) | KR100228949B1 (en) |
| CN (1) | CN1048015C (en) |
| AU (1) | AU695301B2 (en) |
| BR (1) | BR9406946A (en) |
| CA (1) | CA2166721C (en) |
| CZ (1) | CZ3696A3 (en) |
| EG (1) | EG20513A (en) |
| FI (1) | FI943208A (en) |
| HU (1) | HUT74170A (en) |
| IL (1) | IL110175A (en) |
| MX (1) | MX9405132A (en) |
| NO (1) | NO305029B1 (en) |
| NZ (1) | NZ266525A (en) |
| PL (1) | PL312426A1 (en) |
| RU (1) | RU2131876C1 (en) |
| TW (1) | TW316904B (en) |
| WO (1) | WO1995001980A1 (en) |
| ZA (1) | ZA944844B (en) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUT77517A (en) * | 1994-10-20 | 1998-05-28 | Pfizer Inc. | Bicyclic tetrahydro pyrazolopyridines and their use as medicaments |
| JP3107827B2 (en) * | 1995-06-06 | 2000-11-13 | ファイザー・インコーポレーテッド | Tricyclic 5,6-dihydro-9H-pyrazolo [3,4-c] -1,2,4-triazolo [4,3-a] pyridines |
| AP932A (en) * | 1996-08-26 | 2001-02-02 | Pfizer | Tricyclic 5,6-dihydro-9H-pyrazolo (3,4c)-1,2,4,-triazolo (4,3-a) pyridines. |
| KR100338610B1 (en) * | 1996-09-04 | 2002-05-27 | 디. 제이. 우드, 스피겔 알렌 제이 | Indazole Derivatives and Their Use as Inhibitors of Phosphodiesterase (PDE) type IV and the Production of Tumor Necrosis Factor (TNF) |
| US6858616B2 (en) | 1998-12-23 | 2005-02-22 | Bristol-Myers Squibb Pharma Company | Nitrogen containing heterobicycles as factor Xa inhibitors |
| CN100340559C (en) | 1998-12-23 | 2007-10-03 | 布里斯托尔-迈尔斯斯奎布药品公司 | Nitrogen containing heterobicycles as factor XA inhibitors |
| US6326495B2 (en) | 1999-04-30 | 2001-12-04 | Pfizer Inc. | Process for preparing 8-cyclopentyl-6-ethyl-3-[substituted]-5,8-dihydro-4H-1,2,3a,7,8-pentaaza-as-indacenes and intermediates useful therein |
| SI1212089T1 (en) | 1999-08-21 | 2006-08-31 | Altana Pharma Ag | Synergistic combination of roflumilast and salmeterol |
| TWI243055B (en) * | 2000-04-13 | 2005-11-11 | Nippon Zoki Pharmaceutical Co | Pharmaceutical composition for use in treatment of dermatitis |
| EE05405B1 (en) * | 2000-08-10 | 2011-04-15 | Pharmacia Italia S.P.A. | Bit clopazoles acting as kinase inhibitors, process for their preparation, use and pharmaceutical compositions containing them |
| US6960595B2 (en) * | 2001-03-23 | 2005-11-01 | Bristol-Myers Squibb Pharma Company | 5-6 to 5-7 Heterobicycles as factor Xa inhibitors |
| WO2002085353A1 (en) | 2001-04-18 | 2002-10-31 | Bristol-Myers Squibb Company | 1,4,5,6-tetrahydropyrazolo-[3,4-c]-pyridin-7-ones as factor xa inhibitors |
| CA2444571A1 (en) | 2001-04-18 | 2002-10-31 | Bristol-Myers Squibb Company | 1, 4, 5, 6-tetrahydropyrazolo-¬3, 4-c|-pyridin-7-ones as factor xa inhi bitors |
| JP4196678B2 (en) | 2001-04-26 | 2008-12-17 | 味の素株式会社 | Heterocyclic compounds |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| KR101312736B1 (en) | 2003-02-27 | 2013-09-27 | 팔라우 파르마 에스에이 | Pyrazolopyridine derivates |
| US7135469B2 (en) * | 2003-03-18 | 2006-11-14 | Bristol Myers Squibb, Co. | Linear chain substituted monocyclic and bicyclic derivatives as factor Xa inhibitors |
| EP1624893A2 (en) | 2003-04-01 | 2006-02-15 | Applied Research Systems ARS Holding N.V. | Inhibitors of phosphodiesterases in infertility |
| US7145012B2 (en) | 2003-04-23 | 2006-12-05 | Pfizer Inc. | Cannabinoid receptor ligands and uses thereof |
| DE102005031580A1 (en) * | 2005-07-06 | 2007-01-11 | Aicuris Gmbh & Co. Kg | Substituted sulfolanylpyrazoles and their use |
| AR065804A1 (en) * | 2007-03-23 | 2009-07-01 | Smithkline Beecham Corp | COMPOSITE OF INDOL CARBOXAMIDE, PHARMACEUTICAL COMPOSITION THAT UNDERSTANDS IT AND USE OF THIS COMPOUND TO PREPARE A MEDICINAL PRODUCT |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| CN101772513B (en) | 2007-06-04 | 2013-11-13 | 协同医药品公司 | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| ES2522968T3 (en) | 2008-06-04 | 2014-11-19 | Synergy Pharmaceuticals Inc. | Guanylate cyclase agonists useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| JP2011528375A (en) | 2008-07-16 | 2011-11-17 | シナジー ファーマシューティカルズ インコーポレイテッド | Guanylate cyclase agonists useful for the treatment of gastrointestinal disorders, inflammation, cancer, and other disorders |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| CA2828346C (en) | 2011-03-01 | 2021-01-26 | Synergy Pharmaceuticals Inc. | Process of preparing guanylate cyclase c agonists |
| AU2014218599C1 (en) | 2013-02-25 | 2018-09-06 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonists for use in colonic cleansing |
| AU2014235209B2 (en) | 2013-03-15 | 2018-06-14 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonists combined with other drugs |
| JP2016514671A (en) | 2013-03-15 | 2016-05-23 | シナジー ファーマシューティカルズ インコーポレイテッド | Guanylate cyclase agonists and uses thereof |
| WO2014197720A2 (en) | 2013-06-05 | 2014-12-11 | Synergy Pharmaceuticals, Inc. | Ultra-pure agonists of guanylate cyclase c, method of making and using same |
| NZ717739A (en) | 2013-08-09 | 2023-12-22 | Ardelyx Inc | Compounds and methods for inhibiting phosphate transport |
| CN110357888A (en) * | 2018-04-09 | 2019-10-22 | 南京药捷安康生物科技有限公司 | Heterocycle phosphodiesterase inhibitors and application thereof |
| US20200368223A1 (en) | 2019-05-21 | 2020-11-26 | Ardelyx, Inc. | Methods for inhibiting phosphate transport |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3365459A (en) * | 1964-09-08 | 1968-01-23 | Ciba Geigy Corp | Certain tetrahydro pyrazolo-pyridine and pyrazolo-piperidine derivatives |
| FR1463883A (en) * | 1964-09-08 | 1966-07-22 | Ciba Geigy | Process for the preparation of bicyclic triaza-compounds |
| US3340269A (en) * | 1964-09-08 | 1967-09-05 | Ciba Geigy Corp | 1-substituted 4-acyl-2, 3-dioxo-piperidine |
| US5356897A (en) * | 1991-09-09 | 1994-10-18 | Fujisawa Pharmaceutical Co., Ltd. | 3-(heteroaryl)-pyrazololi[1,5-a]pyrimidines |
-
1994
- 1994-06-16 BR BR9406946A patent/BR9406946A/en not_active Application Discontinuation
- 1994-06-16 EP EP94916370A patent/EP0707585A1/en not_active Withdrawn
- 1994-06-16 CA CA002166721A patent/CA2166721C/en not_active Expired - Fee Related
- 1994-06-16 PL PL94312426A patent/PL312426A1/en unknown
- 1994-06-16 AU AU68057/94A patent/AU695301B2/en not_active Ceased
- 1994-06-16 KR KR1019960700019A patent/KR100228949B1/en not_active IP Right Cessation
- 1994-06-16 WO PCT/IB1994/000156 patent/WO1995001980A1/en not_active Application Discontinuation
- 1994-06-16 JP JP7503938A patent/JP2944048B2/en not_active Expired - Lifetime
- 1994-06-16 HU HU9503934A patent/HUT74170A/en unknown
- 1994-06-16 RU RU96103653A patent/RU2131876C1/en active
- 1994-06-16 CN CN94193233A patent/CN1048015C/en not_active Expired - Fee Related
- 1994-06-16 CZ CZ9636A patent/CZ3696A3/en unknown
- 1994-06-16 NZ NZ266525A patent/NZ266525A/en unknown
- 1994-06-17 TW TW083105518A patent/TW316904B/zh active
- 1994-06-30 IL IL11017594A patent/IL110175A/en active IP Right Grant
- 1994-07-05 ZA ZA944844A patent/ZA944844B/en unknown
- 1994-07-05 EG EG40294A patent/EG20513A/en active
- 1994-07-05 FI FI943208A patent/FI943208A/en unknown
- 1994-07-05 MX MX9405132A patent/MX9405132A/en unknown
-
1996
- 1996-01-05 NO NO960056A patent/NO305029B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TW316904B (en) | 1997-10-01 |
| JPH08507084A (en) | 1996-07-30 |
| NZ266525A (en) | 1997-10-24 |
| CN1129940A (en) | 1996-08-28 |
| EG20513A (en) | 1999-06-30 |
| CN1048015C (en) | 2000-01-05 |
| AU695301B2 (en) | 1998-08-13 |
| WO1995001980A1 (en) | 1995-01-19 |
| KR960703852A (en) | 1996-08-31 |
| HU9503934D0 (en) | 1996-03-28 |
| CA2166721C (en) | 1999-07-27 |
| JP2944048B2 (en) | 1999-08-30 |
| ZA944844B (en) | 1996-01-05 |
| NO960056L (en) | 1996-01-05 |
| IL110175A (en) | 2000-01-31 |
| FI943208A (en) | 1995-01-07 |
| IL110175A0 (en) | 1994-10-07 |
| CZ3696A3 (en) | 1997-06-11 |
| AU6805794A (en) | 1995-02-06 |
| BR9406946A (en) | 1996-08-06 |
| KR100228949B1 (en) | 1999-11-01 |
| EP0707585A1 (en) | 1996-04-24 |
| NO960056D0 (en) | 1996-01-05 |
| NO305029B1 (en) | 1999-03-22 |
| HUT74170A (en) | 1996-11-28 |
| RU2131876C1 (en) | 1999-06-20 |
| MX9405132A (en) | 1995-01-31 |
| CA2166721A1 (en) | 1995-01-19 |
| FI943208A0 (en) | 1994-07-05 |
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