PL2895176T3 - Związek pośredni Rywaroksabanu i jego wytwarzanie - Google Patents
Związek pośredni Rywaroksabanu i jego wytwarzanieInfo
- Publication number
- PL2895176T3 PL2895176T3 PL13866539T PL13866539T PL2895176T3 PL 2895176 T3 PL2895176 T3 PL 2895176T3 PL 13866539 T PL13866539 T PL 13866539T PL 13866539 T PL13866539 T PL 13866539T PL 2895176 T3 PL2895176 T3 PL 2895176T3
- Authority
- PL
- Poland
- Prior art keywords
- preparation
- rivaroxaban intermediate
- rivaroxaban
- Prior art date
Links
- DEXXSYVEWAYIGZ-LBPRGKRZSA-N 4-[4-[(5s)-5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl]morpholin-3-one Chemical compound O=C1O[C@@H](CN)CN1C1=CC=C(N2C(COCC2)=O)C=C1 DEXXSYVEWAYIGZ-LBPRGKRZSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
- C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN3358MU2012 | 2012-12-26 | ||
| EP13866539.3A EP2895176B1 (en) | 2012-12-26 | 2013-12-24 | Rivaroxaban intermediate and preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2895176T3 true PL2895176T3 (pl) | 2017-05-31 |
Family
ID=51022156
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL13866539T PL2895176T3 (pl) | 2012-12-26 | 2013-12-24 | Związek pośredni Rywaroksabanu i jego wytwarzanie |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9394292B2 (pl) |
| EP (1) | EP2895176B1 (pl) |
| DK (1) | DK2895176T3 (pl) |
| ES (1) | ES2610020T3 (pl) |
| HR (1) | HRP20161588T1 (pl) |
| HU (1) | HUE032850T2 (pl) |
| PL (1) | PL2895176T3 (pl) |
| PT (1) | PT2895176T (pl) |
| WO (1) | WO2014102820A2 (pl) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016504348A (ja) * | 2012-12-26 | 2016-02-12 | ワンブリー リミテッド | 置換オキサゾリジノンのアルデヒド誘導体 |
| CN104098558B (zh) * | 2014-07-22 | 2016-07-06 | 常州市第四制药厂有限公司 | 酰胺类化合物及其制备方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19962924A1 (de) | 1999-12-24 | 2001-07-05 | Bayer Ag | Substituierte Oxazolidinone und ihre Verwendung |
| DE10300111A1 (de) | 2003-01-07 | 2004-07-15 | Bayer Healthcare Ag | Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid |
| DE102004002044A1 (de) | 2004-01-15 | 2005-08-04 | Bayer Healthcare Ag | Herstellverfahren |
| DE102005045518A1 (de) | 2005-09-23 | 2007-03-29 | Bayer Healthcare Ag | 2-Aminoethoxyessigsäure-Derivate und ihre Verwendung |
| WO2007039132A1 (de) | 2005-10-04 | 2007-04-12 | Bayer Healthcare Ag | Neue polymorphe form und die amorphe form von 5-chlor-n- ( { ( 5s ) -2-0x0-3-[4-( 3-oxo-4-morpholinyl) - phenyl] -1,3-oxazolidin-5-yl} -methyl) -2- thiophencarboxamid |
| DE102006007146A1 (de) | 2006-02-16 | 2007-08-23 | Bayer Healthcare Ag | Aminoacyl-Prodrugs |
| ES2425183T3 (es) | 2007-08-14 | 2013-10-11 | Concert Pharmaceuticals Inc. | Derivados de oxazolidinonas sustituidas |
| US7816355B1 (en) | 2009-04-28 | 2010-10-19 | Apotex Pharmachem Inc | Processes for the preparation of rivaroxaban and intermediates thereof |
| HUE057769T2 (hu) | 2009-07-31 | 2022-06-28 | Krka D D Novo Mesto | Eljárás rivaroxaban kristályosítására |
| CN102822167A (zh) | 2010-01-04 | 2012-12-12 | 埃南蒂亚有限公司 | 用于制备利伐沙班的方法及其中间体 |
| EP2354128A1 (en) | 2010-02-10 | 2011-08-10 | Sandoz Ag | Method for the preparation of rivaroxaban |
| WO2012140061A1 (en) | 2011-04-11 | 2012-10-18 | Sandoz Ag | Method for the preparation of substituted oxazolidinones |
| WO2012153155A1 (en) * | 2011-05-06 | 2012-11-15 | Egis Gyógyszergyár Nyilvãnosan Müködö Részvény-Társaság | Process for the preparation of a rivaroxaban and intermediates formed in said process |
| ES2395304B1 (es) | 2011-05-20 | 2014-01-16 | Interquim, S.A. | Procedimiento de obtención de una tiofen-2-carboxamida. |
| CN103288814B (zh) * | 2012-02-24 | 2016-07-06 | 国药集团国瑞药业有限公司 | 一种利伐沙班中间体的制备方法 |
| JP2016504348A (ja) | 2012-12-26 | 2016-02-12 | ワンブリー リミテッド | 置換オキサゾリジノンのアルデヒド誘導体 |
-
2013
- 2013-12-24 PT PT13866539T patent/PT2895176T/pt unknown
- 2013-12-24 ES ES13866539.3T patent/ES2610020T3/es active Active
- 2013-12-24 EP EP13866539.3A patent/EP2895176B1/en not_active Not-in-force
- 2013-12-24 HU HUE13866539A patent/HUE032850T2/en unknown
- 2013-12-24 PL PL13866539T patent/PL2895176T3/pl unknown
- 2013-12-24 US US14/436,035 patent/US9394292B2/en not_active Expired - Fee Related
- 2013-12-24 WO PCT/IN2013/000799 patent/WO2014102820A2/en not_active Ceased
- 2013-12-24 DK DK13866539.3T patent/DK2895176T3/en active
- 2013-12-24 HR HRP20161588TT patent/HRP20161588T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014102820A2 (en) | 2014-07-03 |
| EP2895176A4 (en) | 2015-09-02 |
| US20150299175A1 (en) | 2015-10-22 |
| ES2610020T3 (es) | 2017-04-25 |
| DK2895176T3 (en) | 2017-01-30 |
| EP2895176A2 (en) | 2015-07-22 |
| EP2895176B1 (en) | 2016-10-19 |
| US9394292B2 (en) | 2016-07-19 |
| HRP20161588T1 (hr) | 2017-01-13 |
| PT2895176T (pt) | 2017-01-27 |
| HUE032850T2 (en) | 2017-11-28 |
| WO2014102820A3 (en) | 2015-02-19 |
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