PL2781519T3 - Nowa przeciwwirusowa pochodna pirolopirydyny i sposób jej wytwarzania - Google Patents

Nowa przeciwwirusowa pochodna pirolopirydyny i sposób jej wytwarzania

Info

Publication number
PL2781519T3
PL2781519T3 PL12849140T PL12849140T PL2781519T3 PL 2781519 T3 PL2781519 T3 PL 2781519T3 PL 12849140 T PL12849140 T PL 12849140T PL 12849140 T PL12849140 T PL 12849140T PL 2781519 T3 PL2781519 T3 PL 2781519T3
Authority
PL
Poland
Prior art keywords
same
production method
novel antiviral
pyrrolopyridine derivative
pyrrolopyridine
Prior art date
Application number
PL12849140T
Other languages
English (en)
Inventor
Jong Chan Son
Bong Jin Kim
Jae Hak Kim
Ill Young Lee
Chang Soo Yun
Sang Ho Lee
Chong Kgo Lee
Original Assignee
St Pharm Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by St Pharm Co., Ltd. filed Critical St Pharm Co., Ltd.
Publication of PL2781519T3 publication Critical patent/PL2781519T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL12849140T 2011-11-15 2012-11-15 Nowa przeciwwirusowa pochodna pirolopirydyny i sposób jej wytwarzania PL2781519T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20110119102 2011-11-15
PCT/KR2012/009689 WO2013073875A1 (ko) 2011-11-15 2012-11-15 신규한 항바이러스성 피롤로피리딘 유도체 및 이의 제조방법
EP12849140.4A EP2781519B1 (en) 2011-11-15 2012-11-15 Novel antiviral pyrrolopyridine derivative and a production method for same

Publications (1)

Publication Number Publication Date
PL2781519T3 true PL2781519T3 (pl) 2020-06-29

Family

ID=48429876

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12849140T PL2781519T3 (pl) 2011-11-15 2012-11-15 Nowa przeciwwirusowa pochodna pirolopirydyny i sposób jej wytwarzania

Country Status (11)

Country Link
US (1) US9499537B2 (pl)
EP (1) EP2781519B1 (pl)
JP (1) JP5893156B2 (pl)
KR (1) KR101467477B1 (pl)
CN (1) CN104066732B (pl)
DK (1) DK2781519T3 (pl)
ES (1) ES2760981T3 (pl)
HU (1) HUE046795T2 (pl)
PL (1) PL2781519T3 (pl)
PT (1) PT2781519T (pl)
WO (1) WO2013073875A1 (pl)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2876370A1 (en) * 2012-07-12 2014-01-16 Viiv Healthcare Uk Limited Compounds and methods for treating hiv
TW201441197A (zh) 2013-01-31 2014-11-01 Shionogi & Co Hiv複製抑制劑
EP2821082A1 (en) 2013-07-05 2015-01-07 Laboratoire Biodim Method of producing an inactivated lentivirus, especially HIV, vaccine, kit and method of use
ES2654242T3 (es) 2014-02-12 2018-02-12 Viiv Healthcare (No.5) Limited Macrociclos de benzotiazol como inhibidores de la réplica del virus de la inmunodeficiencia humana
US9409922B2 (en) 2014-02-18 2016-08-09 Bristol-Myers Squibb Company Imidazopyridine macrocycles as inhibitors of human immunodeficiency virus replication
WO2015126758A1 (en) 2014-02-18 2015-08-27 Bristol-Myers Squibb Company Imidazopyrimidine macrocycles as inhibitors of human immunodeficiency virus replication
EP3152215A1 (en) 2014-02-18 2017-04-12 ViiV Healthcare UK (No.5) Limited Pyrazolopyrimidine macrocycles as inhibitors of human immunodeficiency virus replication
US9273067B2 (en) 2014-02-19 2016-03-01 Bristol-Myers Squibb Company Pyrazolopyrimidine macrocycles as inhibitors of human immunodeficiency virus replication
WO2015174511A1 (ja) 2014-05-16 2015-11-19 塩野義製薬株式会社 Hiv複製阻害作用を有する3環性複素環誘導体
KR101592370B1 (ko) * 2014-06-09 2016-02-11 한국화학연구원 신규한 피롤로피리딘 유도체 및 이의 hiv 저해제로서의 용도
CN104478911A (zh) * 2014-12-19 2015-04-01 成都安斯利生物医药有限公司 一种制备3-三氟甲基吡咯硼酸的方法
WO2016194806A1 (ja) 2015-05-29 2016-12-08 塩野義製薬株式会社 Hiv複製阻害作用を有する含窒素3環性誘導体
PL3604303T3 (pl) * 2017-03-24 2023-04-11 St Pharm Co., Ltd. Nowa pochodna pirolopirydyny, sposób jej wytwarzania oraz jej zastosowanie
WO2018183781A1 (en) 2017-03-29 2018-10-04 Siteone Therapeutics, Inc. 11,13-modified saxitoxins for the treatment of pain
JP7096686B2 (ja) * 2017-03-30 2022-07-06 住友化学株式会社 アミノ基を有する有機リチウム化合物およびその中間体の製造方法、並びに有機リチウム化合物を用いた共役ジエン系重合体の製造方法
MX2022008091A (es) 2020-01-10 2022-07-11 Jiangsu Hengrui Medicine Co Derivado de tetrahidroisoquinolina triciclica, metodo de preparacion del mismo y aplicacion del mismo en medicina.
KR20220023187A (ko) * 2020-08-20 2022-03-02 에스티팜 주식회사 피롤로피리딘 유도체 및 이들의 용도
CA3207714A1 (en) 2021-01-11 2022-07-14 St Pharm Co., Ltd. Pyrrolopyridine derivative preparation method

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0510319A (pt) * 2004-04-26 2007-10-16 Pfizer inibidores da enzima integrase de hiv
DE102004060659A1 (de) * 2004-12-15 2006-07-06 Lanxess Deutschland Gmbh Neue substituierte 1H-Pyrrolo[2,3-b]pyridine und deren Herstellung
US7939545B2 (en) * 2006-05-16 2011-05-10 Boehringer Ingelheim International Gmbh Inhibitors of human immunodeficiency virus replication
GB0710528D0 (en) * 2007-06-01 2007-07-11 Glaxo Group Ltd Novel compounds
US7956068B2 (en) * 2007-11-15 2011-06-07 Boehringer Ingelheim International Gmbh Inhibitors of human immunodeficiency virus replication
WO2009062308A1 (en) 2007-11-16 2009-05-22 Boehringer Ingelheim International Gmbh Inhibitors of human immunodeficiency virus replication
WO2009062285A1 (en) * 2007-11-16 2009-05-22 Boehringer Ingelheim International Gmbh Inhibitors of human immunodeficiency virus replication
GB0908394D0 (en) * 2009-05-15 2009-06-24 Univ Leuven Kath Novel viral replication inhibitors
US8338441B2 (en) * 2009-05-15 2012-12-25 Gilead Sciences, Inc. Inhibitors of human immunodeficiency virus replication
US9029391B2 (en) * 2011-01-24 2015-05-12 Viiv Healthcare Uk Limited Isoquinoline compounds and methods for treating HIV
ES2624984T3 (es) * 2011-07-15 2017-07-18 Viiv Healthcare Uk Limited Derivados de ácido 2-(pirrolo[2,3-b]piridin-5-il)-2-(t-butoxi)-acético como inhibidores de la replicación del VIH para el tratamiento del SIDA

Also Published As

Publication number Publication date
US20140249162A1 (en) 2014-09-04
EP2781519B1 (en) 2019-10-30
US9499537B2 (en) 2016-11-22
EP2781519A1 (en) 2014-09-24
JP2014533298A (ja) 2014-12-11
CN104066732A (zh) 2014-09-24
EP2781519A4 (en) 2015-06-24
CN104066732B (zh) 2016-04-13
ES2760981T3 (es) 2020-05-18
KR20130054211A (ko) 2013-05-24
DK2781519T3 (da) 2019-12-16
KR101467477B1 (ko) 2014-12-02
JP5893156B2 (ja) 2016-03-23
WO2013073875A1 (ko) 2013-05-23
PT2781519T (pt) 2019-12-17
HUE046795T2 (hu) 2020-03-30

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