PL2768859T3 - Antagoniści IL17C do leczenia zaburzeń zapalnych - Google Patents

Antagoniści IL17C do leczenia zaburzeń zapalnych

Info

Publication number
PL2768859T3
PL2768859T3 PL12775247T PL12775247T PL2768859T3 PL 2768859 T3 PL2768859 T3 PL 2768859T3 PL 12775247 T PL12775247 T PL 12775247T PL 12775247 T PL12775247 T PL 12775247T PL 2768859 T3 PL2768859 T3 PL 2768859T3
Authority
PL
Poland
Prior art keywords
treatment
inflammatory disorders
il17c
antagonists
il17c antagonists
Prior art date
Application number
PL12775247T
Other languages
English (en)
Inventor
Andreas Bültmann
Robert MÜHLBACHER
Teresa Garcia
Reginald Christophe Xavier Brys
Luc Nelles
Katja CONRATH
Original Assignee
Morphosys Ag
Galapagos N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Morphosys Ag, Galapagos N.V. filed Critical Morphosys Ag
Publication of PL2768859T3 publication Critical patent/PL2768859T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL12775247T 2011-10-19 2012-10-19 Antagoniści IL17C do leczenia zaburzeń zapalnych PL2768859T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161548744P 2011-10-19 2011-10-19
EP11185763 2011-10-19
EP12775247.5A EP2768859B1 (en) 2011-10-19 2012-10-19 Antagonists of il17c for the treatment of inflammatory disorders
PCT/EP2012/070736 WO2013057241A1 (en) 2011-10-19 2012-10-19 Antagonists of il17c for the treatment of inflammatory disorders

Publications (1)

Publication Number Publication Date
PL2768859T3 true PL2768859T3 (pl) 2018-07-31

Family

ID=48140378

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12775247T PL2768859T3 (pl) 2011-10-19 2012-10-19 Antagoniści IL17C do leczenia zaburzeń zapalnych

Country Status (22)

Country Link
US (2) US20140243506A1 (pl)
EP (2) EP3360897A1 (pl)
JP (1) JP2014530836A (pl)
CN (1) CN103974976A (pl)
AU (1) AU2012324895B2 (pl)
CA (1) CA2852145C (pl)
CY (1) CY1120219T1 (pl)
DK (1) DK2768859T3 (pl)
ES (1) ES2669984T3 (pl)
HR (1) HRP20180776T1 (pl)
HU (1) HUE037087T2 (pl)
LT (1) LT2768859T (pl)
ME (1) ME03073B (pl)
MX (1) MX360710B (pl)
PL (1) PL2768859T3 (pl)
PT (1) PT2768859T (pl)
RS (1) RS57209B1 (pl)
SG (1) SG11201401202YA (pl)
SI (1) SI2768859T1 (pl)
SM (1) SMT201800273T1 (pl)
TR (1) TR201807056T4 (pl)
WO (1) WO2013057241A1 (pl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0913578A2 (pt) 2008-05-14 2017-06-06 Dermtech Int diagnose de melanoma e lentigo solar por análise de ácido nucléico
EP3214442A1 (en) * 2010-10-25 2017-09-06 F. Hoffmann-La Roche AG Treatment of gastrointestinal inflammation and psoriasis and asthmainflammation and psoriasis a
US11578373B2 (en) 2019-03-26 2023-02-14 Dermtech, Inc. Gene classifiers and uses thereof in skin cancers
AU2015367684A1 (en) * 2014-12-15 2017-07-06 Galapagos Nv Antibodies for IL-17C
AR103173A1 (es) 2014-12-22 2017-04-19 Novarits Ag Productos farmacéuticos y composiciones líquidas estables de anticuerpos il-17
HK1257289A1 (zh) 2015-10-05 2019-10-18 Morphosys Ag 治疗和/或预防特应性皮炎的il-17c拮抗剂
IL260733B2 (en) 2016-02-19 2024-03-01 Morphosys Ag Antibodies for il-17c
JP2019517787A (ja) * 2016-05-03 2019-06-27 ザ スクリプス リサーチ インスティテュート 神経変性障害の処置のためのTrkBアゴニスト抗体
WO2019057982A1 (en) 2017-09-25 2019-03-28 Morphosys Ag TREATMENT OF ATOPIC DERMATITIS
US11976332B2 (en) 2018-02-14 2024-05-07 Dermtech, Inc. Gene classifiers and uses thereof in non-melanoma skin cancers
GB201803563D0 (en) 2018-03-06 2018-04-18 Galapagos Nv Antibodies and pharmaceutical compositions thereof for the treatment of autoimmune skin diseases
KR20210031640A (ko) 2018-05-09 2021-03-22 덤테크, 인크. 신규한 유전자 분류자 및 자가면역 질환에서의 이의 용도
KR20210087891A (ko) * 2019-12-30 2021-07-13 경상국립대학교병원 박테리아 감염증 예방 또는 치료용 약학 조성물
CN112795637A (zh) * 2021-01-08 2021-05-14 孙洪臣 靶向il-17c的抑制剂在治疗炎症相关慢性肾脏疾病中的用途
WO2022204375A1 (en) * 2021-03-25 2022-09-29 The Regents Of The University Of Michigan Compositions and methods for detecting, preventing, and treating disturbed microbiota-immune homeostasis

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997008320A1 (en) 1995-08-18 1997-03-06 Morphosys Gesellschaft Für Proteinoptimierung Mbh Protein/(poly)peptide libraries
JP3577586B2 (ja) 1998-05-15 2004-10-13 ジェネンテック・インコーポレーテッド Il−17相同的ポリペプチドとその治療用途
AU781396B2 (en) 1999-07-20 2005-05-19 Morphosys Ag Novel methods for displaying (poly)peptides/proteins on bacteriophage particles via disulfide bonds
ES2506665T3 (es) * 1999-12-23 2014-10-13 Genentech, Inc. Polipéptidos homólogos IL-17 e IL-17R y usos terapéuticos de los mismos
US20040197306A1 (en) * 2000-05-24 2004-10-07 Gorman Daniel M. Mammalian receptor proteins; related reagents and methods
US7771951B2 (en) 2001-12-03 2010-08-10 Amgen Fremont Inc. Antibody categorization based on binding characteristics
KR20070084330A (ko) * 2004-10-18 2007-08-24 지모제넥틱스, 인코포레이티드 가용성 zcytor21, 항-zcytor21 항체 및 결합파트너 및 염증에서의 사용방법
CA2624763A1 (en) * 2005-10-18 2007-04-26 Zymogenetics, Inc. Il-17c antagonists and methods of using the same
CA2666842A1 (en) * 2006-10-18 2008-04-24 Zymogenetics, Inc. Il-17c antagonists and methods of using the same
EP2217268B1 (en) * 2007-12-07 2016-05-04 ZymoGenetics, Inc. Anti-human il-21 monoclonal antibodies
WO2009132821A1 (en) * 2008-04-28 2009-11-05 Giuliani International Limited Interleukin (il-21) binding proteins and methods of making and using same
US20130064788A1 (en) * 2009-10-10 2013-03-14 Eleven Biotherapeutics, Inc. Il-17 family cytokine compositions and uses
EP3214442A1 (en) * 2010-10-25 2017-09-06 F. Hoffmann-La Roche AG Treatment of gastrointestinal inflammation and psoriasis and asthmainflammation and psoriasis a
WO2013016220A1 (en) * 2011-07-22 2013-01-31 Amgen Inc. Il-17 receptor a is required for il-17c biology

Also Published As

Publication number Publication date
CN103974976A (zh) 2014-08-06
PT2768859T (pt) 2018-05-23
DK2768859T3 (en) 2018-06-06
JP2014530836A (ja) 2014-11-20
MX360710B (es) 2018-11-14
AU2012324895B2 (en) 2017-03-16
ES2669984T3 (es) 2018-05-29
LT2768859T (lt) 2018-06-11
NZ623289A (en) 2015-12-24
AU2012324895A1 (en) 2014-04-17
HRP20180776T1 (hr) 2018-08-10
CY1120219T1 (el) 2018-12-12
SG11201401202YA (en) 2014-06-27
EP3360897A1 (en) 2018-08-15
HUE037087T2 (hu) 2018-08-28
TR201807056T4 (tr) 2018-06-21
EP2768859B1 (en) 2018-02-21
US20190062422A1 (en) 2019-02-28
CA2852145A1 (en) 2013-04-25
ME03073B (me) 2019-01-20
CA2852145C (en) 2021-01-12
RS57209B1 (sr) 2018-07-31
US10815297B2 (en) 2020-10-27
MX2014004662A (es) 2015-06-02
EP2768859A1 (en) 2014-08-27
US20140243506A1 (en) 2014-08-28
SMT201800273T1 (it) 2018-07-17
WO2013057241A1 (en) 2013-04-25
SI2768859T1 (en) 2018-06-29

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