PL2683717T3 - Wytwarzanie 3-[2-[4-((6-fluoro-1,2-benzoizoksazol-3-ilo)-1-piperydynylo)-6,7,8,9-tetrahydro-9- hydroksy-2-metylo-4H-pirydo[1,2-a]pirymidyn-4-onu (paliperydonu) i palmitynianu paliperydonu - Google Patents

Wytwarzanie 3-[2-[4-((6-fluoro-1,2-benzoizoksazol-3-ilo)-1-piperydynylo)-6,7,8,9-tetrahydro-9- hydroksy-2-metylo-4H-pirydo[1,2-a]pirymidyn-4-onu (paliperydonu) i palmitynianu paliperydonu

Info

Publication number
PL2683717T3
PL2683717T3 PL12792315.9T PL12792315T PL2683717T3 PL 2683717 T3 PL2683717 T3 PL 2683717T3 PL 12792315 T PL12792315 T PL 12792315T PL 2683717 T3 PL2683717 T3 PL 2683717T3
Authority
PL
Poland
Prior art keywords
paliperidone
benzisoxazol
pyrido
pyrimidin
piperidinyl
Prior art date
Application number
PL12792315.9T
Other languages
English (en)
Inventor
Ravi Ponnaiah
Praveen Kumar Neela
Kosireddy Ravanababu
Kallepally Sudheer
Narasimharao Telagareddy Venkata
Guruswamy Batthini
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of PL2683717T3 publication Critical patent/PL2683717T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL12792315.9T 2011-05-31 2012-05-30 Wytwarzanie 3-[2-[4-((6-fluoro-1,2-benzoizoksazol-3-ilo)-1-piperydynylo)-6,7,8,9-tetrahydro-9- hydroksy-2-metylo-4H-pirydo[1,2-a]pirymidyn-4-onu (paliperydonu) i palmitynianu paliperydonu PL2683717T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN1854CH2011 2011-05-31

Publications (1)

Publication Number Publication Date
PL2683717T3 true PL2683717T3 (pl) 2016-11-30

Family

ID=47258492

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12792315.9T PL2683717T3 (pl) 2011-05-31 2012-05-30 Wytwarzanie 3-[2-[4-((6-fluoro-1,2-benzoizoksazol-3-ilo)-1-piperydynylo)-6,7,8,9-tetrahydro-9- hydroksy-2-metylo-4H-pirydo[1,2-a]pirymidyn-4-onu (paliperydonu) i palmitynianu paliperydonu

Country Status (5)

Country Link
US (1) US8940749B2 (pl)
EP (1) EP2683717B1 (pl)
ES (1) ES2587527T3 (pl)
PL (1) PL2683717T3 (pl)
WO (1) WO2012164582A1 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013080220A2 (en) * 2011-11-28 2013-06-06 Davuluri Rammohan Rao An improved process for the preparation of 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydio-9-hydroxy-2-methyl-4h-pyrido[1,2-a]pyrimidin-4-one.
KR101867988B1 (ko) * 2016-11-02 2018-06-15 주식회사 엔지켐생명과학 팔리페리돈 중간체 및 이를 이용한 팔리페리돈의 제조방법
CN112110914A (zh) * 2019-06-19 2020-12-22 上海天慈中商药业有限公司 一种帕潘立酮棕榈酸酯的制备方法
CN111533737A (zh) * 2020-05-22 2020-08-14 烟台大学 4-氟帕利哌酮棕榈酸酯及其制备方法和应用
CN111440168A (zh) * 2020-05-22 2020-07-24 烟台大学 6-甲氧基帕利哌酮棕榈酸酯制备方法及应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5158952A (en) 1988-11-07 1992-10-27 Janssen Pharmaceutica N.V. 3-[2-[4-(6-fluoro-1,2-benzisoxozol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9 tetrahydro-9-hydroxy-2-methyl-4H-pyrido [1,2-a]pyrimidin-4-one, compositions and method of use
US5254556A (en) * 1988-11-07 1993-10-19 Janssen Pharmaceutica N.V. 3-piperidinyl-1,2-benzisoxazoles
TW487572B (en) * 1996-05-20 2002-05-21 Janssen Pharmaceutica Nv Aqueous suspensions of 9-hydroxyrisperidone fatty acid esters
WO2006114384A1 (en) 2005-04-25 2006-11-02 Janssen Pharmaceutica N.V. Preparation of aseptic 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4h-pyridio[1,2-a]pyrimidin-4-one palmitate ester
US20090048272A1 (en) * 2007-08-16 2009-02-19 Pratap Reddy Padi Preparation of paliperidone
US20090209757A1 (en) * 2008-01-10 2009-08-20 Santiago Ini Processes for the preparation and purification of paliperidone palmitate

Also Published As

Publication number Publication date
ES2587527T3 (es) 2016-10-25
EP2683717A4 (en) 2014-08-27
WO2012164582A1 (en) 2012-12-06
US8940749B2 (en) 2015-01-27
EP2683717A1 (en) 2014-01-15
US20140073787A1 (en) 2014-03-13
EP2683717B1 (en) 2016-05-25

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