PL2603512T3 - Pochodne 6,7-dihydro-3h-oksazolo[3,4-a]pirazyno-5,8-dionu - Google Patents
Pochodne 6,7-dihydro-3h-oksazolo[3,4-a]pirazyno-5,8-dionuInfo
- Publication number
- PL2603512T3 PL2603512T3 PL11815927.6T PL11815927T PL2603512T3 PL 2603512 T3 PL2603512 T3 PL 2603512T3 PL 11815927 T PL11815927 T PL 11815927T PL 2603512 T3 PL2603512 T3 PL 2603512T3
- Authority
- PL
- Poland
- Prior art keywords
- oxazolo
- pyrazine
- dione
- dihydro
- derivatives
- Prior art date
Links
- SPNMSIYOCYTIIH-UHFFFAOYSA-N 6,7-dihydro-3h-[1,3]oxazolo[3,4-a]pyrazine-5,8-dione Chemical class O=C1CNC(=O)C2=COCN12 SPNMSIYOCYTIIH-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/04—Drugs for disorders of the urinary system for urolithiasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D503/02—Preparation
- C07D503/04—Preparation by forming the ring or condensed ring systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37348310P | 2010-08-13 | 2010-08-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2603512T3 true PL2603512T3 (pl) | 2016-09-30 |
Family
ID=45023415
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL11815927.6T PL2603512T3 (pl) | 2010-08-13 | 2011-08-02 | Pochodne 6,7-dihydro-3h-oksazolo[3,4-a]pirazyno-5,8-dionu |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US8338432B2 (pl) |
| EP (1) | EP2603512B1 (pl) |
| JP (1) | JP5940535B2 (pl) |
| KR (1) | KR101871856B1 (pl) |
| CN (1) | CN103108878B (pl) |
| AR (1) | AR082661A1 (pl) |
| BR (1) | BR112013003225B1 (pl) |
| CA (1) | CA2807872C (pl) |
| CL (1) | CL2013000434A1 (pl) |
| CO (1) | CO6680703A2 (pl) |
| DK (1) | DK2603512T3 (pl) |
| EC (1) | ECSP13012486A (pl) |
| ES (1) | ES2565493T3 (pl) |
| HK (1) | HK1184786A1 (pl) |
| HU (1) | HUE027903T2 (pl) |
| IL (1) | IL224683A (pl) |
| MX (1) | MX347632B (pl) |
| PL (1) | PL2603512T3 (pl) |
| RU (1) | RU2581831C2 (pl) |
| UY (1) | UY33535A (pl) |
| WO (1) | WO2012019254A1 (pl) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UY33535A (es) * | 2010-08-13 | 2011-12-01 | Biolab Sanus Farmaceutuca Limitada | Derivados de 6,7-dihidro-3h-oxazolo[3,4]pirazin-5,8-diona |
| AR099523A1 (es) * | 2014-02-24 | 2016-07-27 | Biolab Sanus Farmacêutica Ltda | Compuestos derivados de 6,7-dihidro-3h-oxazolo[3,4-a]pirazina-5,8-diona |
| ES2701273T3 (es) * | 2014-09-12 | 2019-02-21 | Biolab Sanus Farmaceutica Ltda | Derivados de piridopirimidinas |
| CA3144770A1 (en) * | 2019-07-15 | 2021-01-21 | Biolab Sanus Farmaceutica Ltda | Stereoisomers of the compound 3-(benzo[d][1,3]dioxol-5-yl)-7-(1-hydroxypropan-2-yl)-1-(1h-indol-3-yl)-6,7-dihydro-3h-oxazol[3,4-a]pyrazine-5,8-dione and use thereof as an antitumor agent and phosphodiesterase enzyme inhibitor |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5698560A (en) | 1995-03-01 | 1997-12-16 | Kyowa Hakko Kogyo Co., Ltd. | Imidazoquinazoline derivatives |
| GB9514464D0 (en) * | 1995-07-14 | 1995-09-13 | Glaxo Lab Sa | Medicaments |
| MXPA03011082A (es) * | 2001-06-05 | 2004-07-08 | Lilly Icos Llc | Derivados de pirazino-1',2': 1,6-prirido-3,4-b-indol-1,4-diona. |
| WO2003000691A1 (en) * | 2001-06-21 | 2003-01-03 | Lilly Icos Llc | Carboline derivatives as pdev inhibitors |
| AR045950A1 (es) | 2003-10-09 | 2005-11-16 | Speedel Experimenta Ag | Compuestos derivados de piperazina, composiciones farmaceuticas que los contienen y su uso en la fabricacion de medicamentos. |
| ATE417849T1 (de) | 2004-04-07 | 2009-01-15 | Pfizer | Pyrazoloä4,3-düpyrimidine |
| RU2418590C2 (ru) * | 2006-04-04 | 2011-05-20 | Донг-А Фарматех Ко. Лтд. | Средство для предупреждения и лечения гиперплазии предстательной железы, содержащее производное пиразолопиримидинона |
| BRPI0903803B1 (pt) * | 2009-09-30 | 2019-07-09 | Biolab Sanus Farmacêutica Ltda. | Composto, processo de preparação, composição farmacêutica e uso dos compostos |
| UY33535A (es) * | 2010-08-13 | 2011-12-01 | Biolab Sanus Farmaceutuca Limitada | Derivados de 6,7-dihidro-3h-oxazolo[3,4]pirazin-5,8-diona |
-
2011
- 2011-07-27 UY UY0001033535A patent/UY33535A/es active IP Right Grant
- 2011-08-02 BR BR112013003225-1A patent/BR112013003225B1/pt active IP Right Grant
- 2011-08-02 ES ES11815927.6T patent/ES2565493T3/es active Active
- 2011-08-02 EP EP11815927.6A patent/EP2603512B1/en active Active
- 2011-08-02 CA CA2807872A patent/CA2807872C/en active Active
- 2011-08-02 KR KR1020137006343A patent/KR101871856B1/ko active IP Right Grant
- 2011-08-02 PL PL11815927.6T patent/PL2603512T3/pl unknown
- 2011-08-02 DK DK11815927.6T patent/DK2603512T3/en active
- 2011-08-02 RU RU2013110795/04A patent/RU2581831C2/ru active
- 2011-08-02 HU HUE11815927A patent/HUE027903T2/hu unknown
- 2011-08-02 JP JP2013523443A patent/JP5940535B2/ja active Active
- 2011-08-02 WO PCT/BR2011/000255 patent/WO2012019254A1/en active Application Filing
- 2011-08-02 MX MX2013001692A patent/MX347632B/es active IP Right Grant
- 2011-08-02 CN CN201180039626.8A patent/CN103108878B/zh active Active
- 2011-08-02 US US13/196,363 patent/US8338432B2/en active Active
- 2011-08-09 AR ARP110102892A patent/AR082661A1/es active IP Right Grant
-
2013
- 2013-02-12 CL CL2013000434A patent/CL2013000434A1/es unknown
- 2013-02-12 IL IL224683A patent/IL224683A/en active IP Right Grant
- 2013-03-08 CO CO13046988A patent/CO6680703A2/es active IP Right Grant
- 2013-03-12 EC ECSP13012486 patent/ECSP13012486A/es unknown
- 2013-10-30 HK HK13112233.7A patent/HK1184786A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUE027903T2 (hu) | 2016-11-28 |
| ECSP13012486A (es) | 2013-04-30 |
| CO6680703A2 (es) | 2013-05-31 |
| KR20130109110A (ko) | 2013-10-07 |
| WO2012019254A1 (en) | 2012-02-16 |
| EP2603512A4 (en) | 2014-07-16 |
| EP2603512B1 (en) | 2015-12-30 |
| KR101871856B1 (ko) | 2018-06-28 |
| UY33535A (es) | 2011-12-01 |
| RU2581831C2 (ru) | 2016-04-20 |
| AR082661A1 (es) | 2012-12-26 |
| CN103108878B (zh) | 2016-01-27 |
| BR112013003225B1 (pt) | 2021-03-30 |
| CL2013000434A1 (es) | 2013-06-07 |
| MX347632B (es) | 2017-05-04 |
| US20120040988A1 (en) | 2012-02-16 |
| JP5940535B2 (ja) | 2016-06-29 |
| ES2565493T3 (es) | 2016-04-05 |
| CA2807872C (en) | 2018-07-24 |
| CA2807872A1 (en) | 2012-02-16 |
| DK2603512T3 (en) | 2016-04-04 |
| MX2013001692A (es) | 2013-03-18 |
| CN103108878A (zh) | 2013-05-15 |
| HK1184786A1 (zh) | 2014-01-30 |
| JP2013533290A (ja) | 2013-08-22 |
| RU2013110795A (ru) | 2014-09-20 |
| US8338432B2 (en) | 2012-12-25 |
| BR112013003225A2 (pt) | 2016-06-07 |
| IL224683A (en) | 2016-03-31 |
| EP2603512A1 (en) | 2013-06-19 |
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