PL2563932T3 - Wykrywanie komórek odpornościowych, w szczególności komórek T poprzez analizę metylacji DNA genów CCR6 - Google Patents

Wykrywanie komórek odpornościowych, w szczególności komórek T poprzez analizę metylacji DNA genów CCR6

Info

Publication number
PL2563932T3
PL2563932T3 PL11716573T PL11716573T PL2563932T3 PL 2563932 T3 PL2563932 T3 PL 2563932T3 PL 11716573 T PL11716573 T PL 11716573T PL 11716573 T PL11716573 T PL 11716573T PL 2563932 T3 PL2563932 T3 PL 2563932T3
Authority
PL
Poland
Prior art keywords
cells
ccr6
genes
dna
detection
Prior art date
Application number
PL11716573T
Other languages
English (en)
Inventor
Sven Olek
Original Assignee
Epiontis Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epiontis Gmbh filed Critical Epiontis Gmbh
Publication of PL2563932T3 publication Critical patent/PL2563932T3/pl

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2523/00Reactions characterised by treatment of reaction samples
    • C12Q2523/10Characterised by chemical treatment
    • C12Q2523/125Bisulfite(s)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/154Methylation markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL11716573T 2010-04-29 2011-04-29 Wykrywanie komórek odpornościowych, w szczególności komórek T poprzez analizę metylacji DNA genów CCR6 PL2563932T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32922910P 2010-04-29 2010-04-29
PCT/EP2011/056871 WO2011135088A1 (en) 2010-04-29 2011-04-29 Detection of immune cells, in particular t cells through dna-methylation analysis of the genes ccr6 and blr1
EP11716573.8A EP2563932B1 (en) 2010-04-29 2011-04-29 Detection of immune cells, in particular t cells through dna-methylation analysis of the genes ccr6

Publications (1)

Publication Number Publication Date
PL2563932T3 true PL2563932T3 (pl) 2018-07-31

Family

ID=44022865

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11716573T PL2563932T3 (pl) 2010-04-29 2011-04-29 Wykrywanie komórek odpornościowych, w szczególności komórek T poprzez analizę metylacji DNA genów CCR6

Country Status (7)

Country Link
US (2) US9783846B2 (pl)
EP (1) EP2563932B1 (pl)
JP (2) JP6062850B2 (pl)
DK (1) DK2563932T3 (pl)
ES (1) ES2657846T3 (pl)
PL (1) PL2563932T3 (pl)
WO (1) WO2011135088A1 (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2563932T3 (pl) * 2010-04-29 2018-07-31 Epiontis Gmbh Wykrywanie komórek odpornościowych, w szczególności komórek T poprzez analizę metylacji DNA genów CCR6
AU2011317211B2 (en) * 2010-10-22 2015-04-16 Dana-Farber Cancer Institute, Inc. Discovery of regulatory T cells programmed to suppress an immune response
US10548957B2 (en) 2012-09-28 2020-02-04 Dana-Farber Cancer Institute, Inc. Targeted expansion of Qa-1-peptide-specific regulatory CD8 T cells to ameliorate arthritis
EP3561074B1 (en) 2013-04-19 2024-03-20 Precision for Medicine GmbH Method for identifying the quantitative cellular composition in a biological sample
WO2016033329A1 (en) 2014-08-27 2016-03-03 Dana-Farber Cancer Institute, Inc. Intracellular osteopontin regulates the lineage commitment of lymphoid subsets
CN109477073B (zh) * 2016-03-31 2024-04-12 来恩生物医药私人有限公司 表达外源病毒特异性t细胞受体(tcr)的非活化t细胞
WO2018027228A1 (en) * 2016-08-05 2018-02-08 The Regents Of The University Of California Dna methylation based predictor of mortality
DE102018112644B4 (de) * 2018-05-25 2020-06-10 Epiontis Gmbh CXCR3 als epigenetischer Marker zur Identifizierung von inflammatorischen Immunzellen, insbesondere CD8+ Gedächnis-T-Zellen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6110695A (en) 1997-12-02 2000-08-29 The Regents Of The University Of California Modulating the interaction of the chemokine, B Lymphocyte Hemoattractant, and its Receptor, BLR1
WO2003014153A2 (en) 2001-08-10 2003-02-20 Topigen Pharmaceutique Inc. Cellular virus receptors and methods of use.
EP1718766A4 (en) * 2004-02-10 2009-05-27 Cornell Res Foundation Inc METHOD FOR DETECTING PROMOTER METHYLATION STATE
PL2563932T3 (pl) * 2010-04-29 2018-07-31 Epiontis Gmbh Wykrywanie komórek odpornościowych, w szczególności komórek T poprzez analizę metylacji DNA genów CCR6

Also Published As

Publication number Publication date
DK2563932T3 (en) 2018-03-05
US10590475B2 (en) 2020-03-17
US20170327871A1 (en) 2017-11-16
US9783846B2 (en) 2017-10-10
JP2013524828A (ja) 2013-06-20
EP2563932B1 (en) 2017-11-29
JP6062850B2 (ja) 2017-01-25
EP2563932A1 (en) 2013-03-06
JP2016208977A (ja) 2016-12-15
WO2011135088A1 (en) 2011-11-03
ES2657846T3 (es) 2018-03-07
US20130089861A1 (en) 2013-04-11

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