PL2314580T3 - Sposób wytwarzania syntetycznych kannabinoidów - Google Patents

Sposób wytwarzania syntetycznych kannabinoidów

Info

Publication number
PL2314580T3
PL2314580T3 PL10004422T PL10004422T PL2314580T3 PL 2314580 T3 PL2314580 T3 PL 2314580T3 PL 10004422 T PL10004422 T PL 10004422T PL 10004422 T PL10004422 T PL 10004422T PL 2314580 T3 PL2314580 T3 PL 2314580T3
Authority
PL
Poland
Prior art keywords
producing synthetic
synthetic cannabinoids
cannabinoids
producing
synthetic
Prior art date
Application number
PL10004422T
Other languages
English (en)
Inventor
Christian Steup
Thomas Herkenroth
Original Assignee
The Health Concept Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Health Concept Gmbh filed Critical The Health Concept Gmbh
Publication of PL2314580T3 publication Critical patent/PL2314580T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/80Dibenzopyrans; Hydrogenated dibenzopyrans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/50Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions decreasing the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/36Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/42Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
PL10004422T 2009-04-30 2010-04-27 Sposób wytwarzania syntetycznych kannabinoidów PL2314580T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102009019322A DE102009019322A1 (de) 2009-04-30 2009-04-30 Verfahren zur Herstellung von Synthetischen Cannabinoiden
EP10004422.1A EP2314580B1 (de) 2009-04-30 2010-04-27 Verfahren zur Herstellung von synthetischen Cannabinoiden

Publications (1)

Publication Number Publication Date
PL2314580T3 true PL2314580T3 (pl) 2016-02-29

Family

ID=42932300

Family Applications (1)

Application Number Title Priority Date Filing Date
PL10004422T PL2314580T3 (pl) 2009-04-30 2010-04-27 Sposób wytwarzania syntetycznych kannabinoidów

Country Status (5)

Country Link
US (1) US20100298579A1 (pl)
EP (1) EP2314580B1 (pl)
DE (1) DE102009019322A1 (pl)
ES (1) ES2554653T3 (pl)
PL (1) PL2314580T3 (pl)

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DK2760444T3 (da) 2011-09-29 2020-07-27 Thc Pharm Gmbh The Health Concept Cannabinoidcarboxylsyrer, salte af cannabinoidcarboxylsyrer, fremstilling og anvendelse deraf
JP6581509B2 (ja) * 2013-02-28 2019-09-25 ティーウィノット テクノロジーズ リミテッド 化合物を合成する化学工学プロセス及び装置
ES2547354T3 (es) * 2013-09-03 2015-10-05 Symrise Ag Mezclas de compuestos cannabinoides, su preparación y uso
WO2016030828A1 (en) 2014-08-25 2016-03-03 Full Spectrum Laboratories Limited Apparatus and methods for the simultaneous production of cannabinoid compounds
EP3232808B1 (de) 2014-12-19 2020-04-01 THC Pharm GmbH The Health Concept Cbd-haltiges getränk
AU2016215094B2 (en) * 2015-02-05 2019-09-26 Colorado Can Llc Purified CBD and CBDA, and methods, compositions and products employing CBD or CBDA
EP3061450A1 (de) * 2015-02-26 2016-08-31 Symrise AG Mischungen cannabinoider Verbindungen, deren Herstellung und Verwendung
AU2016225026A1 (en) 2015-02-27 2017-09-07 Canopy Growth Corporation Compositions comprising combinations of purified cannabinoids, with at least one flavonoid, terpene, or mineral
US20170008869A1 (en) * 2015-07-10 2017-01-12 Noramco, Inc. Process for the production of cannabidiol and delta-9-tetrahydrocannabinol
EP3150264A1 (de) * 2015-09-30 2017-04-05 Bionorica Ethics GmbH Vakuumdestillation zur anreicherung von cbd
PL3455213T3 (pl) 2016-05-13 2022-04-04 Symrise Ag Sposób oczyszczania związków kannabinoidowych przez symulowaną chromatografię z ruchomym złożem
US10399920B2 (en) 2016-06-01 2019-09-03 S&B Pharma, Inc. Crystalline form of cannabidiol
US10568865B2 (en) 2016-08-29 2020-02-25 Canopy Growth Corporation Water soluble compositions comprising purified cannabinoids
US12485129B2 (en) 2016-08-29 2025-12-02 Canopy Growth Corporation Water soluble compositions comprising purified cannabinoids
US10239808B1 (en) 2016-12-07 2019-03-26 Canopy Holdings, LLC Cannabis extracts
CN106810426B (zh) * 2016-12-29 2020-05-08 暨明医药科技(苏州)有限公司 一种大麻二酚的合成方法
CA3054690A1 (en) * 2017-03-01 2018-09-07 Canopy Growth Corporation Compositions purposefully selected comprising purified cannabinoids and/or purified terpenes
CN111032088A (zh) * 2017-06-20 2020-04-17 耶路撒冷希伯来大学伊森姆研究发展有限公司 大麻二酚酸酯类组合物及其用途
BR112020003138A2 (pt) * 2017-08-16 2020-08-11 The University Of Sydney método para descarboxilar um composto fitocanabinoide carboxilado e método para preparar um composto fitocanabinóide
EP3461545A1 (de) 2017-09-30 2019-04-03 Bionorica Ethics GmbH Kurzwegdestillation im vakuum zur anreicherung von naturstoffen
EP3745884A1 (en) 2018-01-31 2020-12-09 Canopy Holdings, Llc Hemp powder
BR102018002843A2 (pt) * 2018-02-09 2019-08-27 Prati Donaduzzi & Cia Ltda composição farmacêutica e uso da mesma
US11851415B2 (en) * 2018-03-07 2023-12-26 Cleen Technology Inc. Continuous isolation of cannabidiol and cannabinoids and conversion of cannabidiol to delta 8-tetrahydrocannabinol and delta 9-tetrahydrocannabinol
US11192870B2 (en) * 2018-03-07 2021-12-07 Socati Technologies—Oregon, Llc Continuous isolation of cannabidiol and conversion of cannabidiol to delta 8-tetrahydrocannabinol and delta 9-tetrahydrocannabinol
DE102018001959A1 (de) 2018-03-10 2019-09-12 Florian Frey Thermisches Trennverfahren zur Anreicherung von Cannabinoiden
WO2019222459A1 (en) 2018-05-18 2019-11-21 Diverse Biotech, Inc. Cannabinoid preparations and therapeutic uses
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CA3119729A1 (en) 2018-10-10 2020-04-16 Treehouse Biotech, Inc. Synthesis of cannabigerol
WO2020117288A1 (en) * 2018-12-07 2020-06-11 Mckinney Jeffrey A Deuterated agonists and methods of use
CA3130763A1 (en) 2019-02-25 2020-09-03 Ginkgo Bioworks, Inc. Biosynthesis of cannabinoids and cannabinoid precursors
CN118831076A (zh) * 2019-03-12 2024-10-25 Epm (Ip)公司 大麻素酸酯组合物及其用途
WO2020214574A1 (en) * 2019-04-15 2020-10-22 Trustees Of Boston University One-step flow-mediated synthesis of cannabidiol (cbd) and derivatives
CN113950467A (zh) * 2019-05-10 2022-01-18 贝努维亚制造有限责任公司 生产大麻二酚或次大麻二酚的方法以及生产大麻二酚或次大麻二酚的中间体
CN111943813B (zh) * 2019-05-17 2023-04-14 上海特化医药科技有限公司 大麻二酚类化合物的制备方法
US10799546B1 (en) 2019-07-26 2020-10-13 Biomass Oil Separation Solutions, Llc Modular, integrated process and apparatus for extracting, refining and remediating active substances from plant material
JP2022545491A (ja) * 2019-08-22 2022-10-27 イーピーエム(アイピー), インコーポレイテッド カンナビノイド酸エステル組成物およびその使用
US11542243B1 (en) 2019-09-26 2023-01-03 FusionFarms, LLC Method of converting delta9-THC to delta10-THC and the purification of the delta10-THC by crystallization
CA3162971A1 (en) * 2019-12-27 2021-07-01 Charles K. Marlowe Preparation of cannabichromene and related cannabinoids
US12545694B2 (en) 2020-01-08 2026-02-10 Chengdu Baiyu Pharmaceutical Co., Ltd. Cannabidiol derivatives, preparation method thereof and use thereof
US12391711B2 (en) 2020-01-08 2025-08-19 Chengdu Baiyu Pharmaceutical Co., Ltd. Tetrahydrocannabinol derivatives, preparation method thereof and use thereof
CN113087599A (zh) * 2020-01-08 2021-07-09 成都百裕制药股份有限公司 大麻二酚衍生物及其制备方法和在医药上的应用
EP3868736B1 (en) 2020-02-21 2022-11-30 SCI Pharmtech Inc Solvent-free method for preparing cannabinoids
JP7714571B2 (ja) 2020-03-31 2025-07-29 フィトセラピューティクス・リミテッド テルペンフェノール化合物およびそれらの使用
US20210355097A1 (en) * 2020-05-12 2021-11-18 FinChemica, Inc. Catalytic conversation of cannabidiol and methods thereof
CA3132439A1 (en) 2020-05-12 2021-11-12 Canopy Growth Corporation Methods of synthesizing cannabigergol, cannabigerolic acid, and analogs thereof
CN111848365A (zh) * 2020-07-16 2020-10-30 云南自由贸易试验区睿之成医药科技有限公司 一种大麻二酚的合成方法
CN113173857B (zh) * 2021-03-09 2023-05-23 昆明理工大学 一种大麻二酚衍生物及其制备方法与应用
CN113603568A (zh) * 2021-07-19 2021-11-05 厦门朝阳生物工程有限公司 一种大麻二酚的制备方法
CA3263937A1 (en) 2022-08-05 2024-02-08 Salud & Semillas, S.L. SYNTHESIS OF CANNABINOIDS FROM OLIVETOL AND TERPENE IN DICHLOROMETHANE WITH FECL3 * 6H2O AS A CATALYST
JP2026501608A (ja) * 2022-12-29 2026-01-16 アドテック ファーマ インコーポレイテッド 眼の状態の治療のためのナビロンを含む医薬組成物
EP4431169A1 (en) 2023-03-17 2024-09-18 Siegfried AG Method of purifying cannabinoid components from plant extracts

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5342971A (en) 1992-12-29 1994-08-30 The Australian National University Process for the preparation of dibenzo[b,d]pyrans

Also Published As

Publication number Publication date
EP2314580A1 (de) 2011-04-27
ES2554653T3 (es) 2015-12-22
DE102009019322A1 (de) 2010-11-11
US20100298579A1 (en) 2010-11-25
EP2314580B1 (de) 2015-09-09

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