PL2122364T3 - Sposób identyfikacji agonistycznej aktywności związku docelowego w kanale jonów potasowych - Google Patents
Sposób identyfikacji agonistycznej aktywności związku docelowego w kanale jonów potasowychInfo
- Publication number
- PL2122364T3 PL2122364T3 PL08707734T PL08707734T PL2122364T3 PL 2122364 T3 PL2122364 T3 PL 2122364T3 PL 08707734 T PL08707734 T PL 08707734T PL 08707734 T PL08707734 T PL 08707734T PL 2122364 T3 PL2122364 T3 PL 2122364T3
- Authority
- PL
- Poland
- Prior art keywords
- identifying
- target compound
- potassium channel
- agonistic activity
- agonistic
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102007012029A DE102007012029A1 (de) | 2007-03-13 | 2007-03-13 | Verfahren zur Identifizierung der agonistischen Aktivität einer Zielverbindung auf einen Kaliumkanal |
| PCT/EP2008/001161 WO2008110247A1 (de) | 2007-03-13 | 2008-02-15 | Verfahren zur identifizierung der agonistischen aktivität einer zielverbindung auf einen kaliumkanal |
| EP08707734A EP2122364B1 (de) | 2007-03-13 | 2008-02-15 | Verfahren zur identifizierung der agonistischen aktivität einer zielverbindung auf einen kaliumkanal |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2122364T3 true PL2122364T3 (pl) | 2013-04-30 |
Family
ID=39256928
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL08707734T PL2122364T3 (pl) | 2007-03-13 | 2008-02-15 | Sposób identyfikacji agonistycznej aktywności związku docelowego w kanale jonów potasowych |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20080227819A1 (pl) |
| EP (1) | EP2122364B1 (pl) |
| DE (1) | DE102007012029A1 (pl) |
| ES (1) | ES2399939T3 (pl) |
| HK (1) | HK1136633A1 (pl) |
| PL (1) | PL2122364T3 (pl) |
| TW (1) | TW200900699A (pl) |
| WO (1) | WO2008110247A1 (pl) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9134307B2 (en) * | 2007-07-11 | 2015-09-15 | X-Body, Inc. | Method for determining ion channel modulating properties of a test reagent |
| US8323911B2 (en) * | 2010-05-13 | 2012-12-04 | University Of South Carolina | High throughput assay for discovering new inhibitors of the GIRK1/4 channel |
| WO2021113802A1 (en) * | 2019-12-06 | 2021-06-10 | Icahn School Of Medicine At Mount Sinai | Method of treatment with kcnq channel openers |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040175691A1 (en) * | 1998-12-03 | 2004-09-09 | Brown Barry S. | Use of the KCNQ2 and KCNQ3 genes for the discovery of agents useful in the treatment of neurological disorders |
| US6329367B1 (en) | 1998-12-18 | 2001-12-11 | Novo Nordisk A/S | Fused 1,2,4-thiadiazine derivatives, their preparation and use |
| EP1327150A1 (en) * | 2000-10-13 | 2003-07-16 | Bristol-Myers Squibb Company | Methods for detecting modulators of ion channels using thallium (i) sensitive assays |
| US6348486B1 (en) | 2000-10-17 | 2002-02-19 | American Home Products Corporation | Methods for modulating bladder function |
| US6852504B2 (en) * | 2001-08-08 | 2005-02-08 | Molecular Devices Corporation | Method for measuring cellular transmembrane potential changes |
| WO2005111228A1 (ja) | 2004-05-18 | 2005-11-24 | Mitsubishi Pharma Corporation | ミトコンドリアの膜電位を変化させる物質の評価方法 |
-
2007
- 2007-03-13 DE DE102007012029A patent/DE102007012029A1/de not_active Withdrawn
-
2008
- 2008-02-15 PL PL08707734T patent/PL2122364T3/pl unknown
- 2008-02-15 EP EP08707734A patent/EP2122364B1/de not_active Not-in-force
- 2008-02-15 ES ES08707734T patent/ES2399939T3/es active Active
- 2008-02-15 WO PCT/EP2008/001161 patent/WO2008110247A1/de active Application Filing
- 2008-02-26 TW TW097106626A patent/TW200900699A/zh unknown
- 2008-03-13 US US12/047,989 patent/US20080227819A1/en not_active Abandoned
-
2010
- 2010-05-04 HK HK10104384.4A patent/HK1136633A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008110247A1 (de) | 2008-09-18 |
| EP2122364A1 (de) | 2009-11-25 |
| TW200900699A (en) | 2009-01-01 |
| HK1136633A1 (en) | 2010-07-02 |
| ES2399939T3 (es) | 2013-04-04 |
| EP2122364B1 (de) | 2012-11-21 |
| WO2008110247A8 (de) | 2008-11-13 |
| DE102007012029A1 (de) | 2008-09-18 |
| US20080227819A1 (en) | 2008-09-18 |
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