PL1902010T3 - Sposób wytwarzania adapalenu i związków pokrewnych - Google Patents
Sposób wytwarzania adapalenu i związków pokrewnychInfo
- Publication number
- PL1902010T3 PL1902010T3 PL06848698T PL06848698T PL1902010T3 PL 1902010 T3 PL1902010 T3 PL 1902010T3 PL 06848698 T PL06848698 T PL 06848698T PL 06848698 T PL06848698 T PL 06848698T PL 1902010 T3 PL1902010 T3 PL 1902010T3
- Authority
- PL
- Poland
- Prior art keywords
- adapalene
- preparation
- related compounds
- compounds
- Prior art date
Links
- LZCDAPDGXCYOEH-UHFFFAOYSA-N adapalene Chemical compound C1=C(C(O)=O)C=CC2=CC(C3=CC=C(C(=C3)C34CC5CC(CC(C5)C3)C4)OC)=CC=C21 LZCDAPDGXCYOEH-UHFFFAOYSA-N 0.000 title 1
- 229960002916 adapalene Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
- C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
- C07C65/26—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic containing rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/02—Preparation of carboxylic acids or their salts, halides or anhydrides from salts of carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/41—Preparation of salts of carboxylic acids
- C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/43—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/47—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/50—Use of additives, e.g. for stabilisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
- C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/58—Ring systems containing bridged rings containing three rings
- C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
- C07C2603/74—Adamantanes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Crystallography & Structural Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69125905P | 2005-06-17 | 2005-06-17 | |
| PCT/IB2006/003987 WO2007072217A2 (en) | 2005-06-17 | 2006-06-16 | Process for the preparation of adapalene and related compounds |
| EP06848698A EP1902010B1 (en) | 2005-06-17 | 2006-06-16 | Process for the preparation of adapalene and related compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1902010T3 true PL1902010T3 (pl) | 2012-04-30 |
Family
ID=38189034
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL06848698T PL1902010T3 (pl) | 2005-06-17 | 2006-06-16 | Sposób wytwarzania adapalenu i związków pokrewnych |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US8119834B2 (pl) |
| EP (1) | EP1902010B1 (pl) |
| AR (1) | AR058009A1 (pl) |
| AT (1) | ATE535506T1 (pl) |
| CA (1) | CA2612497C (pl) |
| ES (1) | ES2378085T3 (pl) |
| PL (1) | PL1902010T3 (pl) |
| SI (1) | SI1902010T1 (pl) |
| WO (1) | WO2007072217A2 (pl) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI1902010T1 (sl) * | 2005-06-17 | 2012-07-31 | Medichem Sa | Postopek za pripravo adapalena in odvisnih spojin |
| WO2007125542A2 (en) * | 2006-05-03 | 2007-11-08 | Usv Limited | A process for preparation of adapalene |
| CN112479867B (zh) * | 2020-12-30 | 2024-03-29 | 武汉诺安药业有限公司 | 一种阿达帕林微粉化的化学制备方法 |
| CN119104641A (zh) * | 2024-08-29 | 2024-12-10 | 湖北广济医药科技有限公司 | 一种利用hplc方法检测阿达帕林起始物料杂质的方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LU85849A1 (fr) * | 1985-04-11 | 1986-11-05 | Cird | Derives benzonaphtaleniques,leur procede de preparation et leur application dans les domaines pharmaceutiques et cosmetiques |
| FR2636061B1 (fr) * | 1988-09-07 | 1990-11-09 | Cird | Procede de preparation de derives de l'adamantane-1 |
| PT1485080E (pt) * | 2002-03-12 | 2009-07-31 | Galderma Res & Dev | Utilização de adapaleno para o tratamento de desordens dermatológicas |
| RU2414449C2 (ru) | 2005-04-08 | 2011-03-20 | Галдерма Ресерч Энд Девелопмент | Новый способ получения 6-[3-(1-адамантил)-4-метоксифенил]-2-нафтойной кислоты |
| SI1902010T1 (sl) * | 2005-06-17 | 2012-07-31 | Medichem Sa | Postopek za pripravo adapalena in odvisnih spojin |
-
2006
- 2006-06-16 SI SI200631276T patent/SI1902010T1/sl unknown
- 2006-06-16 WO PCT/IB2006/003987 patent/WO2007072217A2/en not_active Ceased
- 2006-06-16 AT AT06848698T patent/ATE535506T1/de active
- 2006-06-16 ES ES06848698T patent/ES2378085T3/es active Active
- 2006-06-16 CA CA2612497A patent/CA2612497C/en not_active Expired - Fee Related
- 2006-06-16 PL PL06848698T patent/PL1902010T3/pl unknown
- 2006-06-16 US US11/922,353 patent/US8119834B2/en not_active Expired - Fee Related
- 2006-06-16 EP EP06848698A patent/EP1902010B1/en not_active Not-in-force
- 2006-06-20 AR ARP060102631A patent/AR058009A1/es unknown
-
2012
- 2012-01-27 US US13/359,793 patent/US8871972B2/en not_active Expired - Fee Related
-
2014
- 2014-10-06 US US14/507,114 patent/US20150141696A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20150141696A1 (en) | 2015-05-21 |
| ATE535506T1 (de) | 2011-12-15 |
| US20090131713A1 (en) | 2009-05-21 |
| US8119834B2 (en) | 2012-02-21 |
| SI1902010T1 (sl) | 2012-07-31 |
| EP1902010A2 (en) | 2008-03-26 |
| WO2007072217A2 (en) | 2007-06-28 |
| US8871972B2 (en) | 2014-10-28 |
| EP1902010B1 (en) | 2011-11-30 |
| CA2612497A1 (en) | 2007-06-28 |
| AR058009A1 (es) | 2008-01-23 |
| US20130030214A1 (en) | 2013-01-31 |
| WO2007072217A3 (en) | 2007-11-01 |
| ES2378085T3 (es) | 2012-04-04 |
| CA2612497C (en) | 2015-10-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL188330A0 (en) | Processes for the preparation of | |
| IL185974A0 (en) | Process for the preparation of opioid modulators | |
| ZA200804264B (en) | Process for the preparation of ferri-succinylcasein | |
| IL196481A0 (en) | Process for the preparation of levetiracetam | |
| IL218351A0 (en) | Process for the preparation of amines | |
| EP1922345A4 (en) | PROCESS FOR THE PREPARATION OF COPOLYMER-1 | |
| SI1844036T1 (sl) | Postopek za pripravo aripiprazola | |
| IL213474A0 (en) | Processes for the preparation of cyclopropyl-amide derivatives | |
| IL184193A0 (en) | Processes for the preparation of aminoethoxybenzyl alcohols | |
| IL190325A (en) | A process for making loopfin | |
| ZA200601910B (en) | Process for the preparation of organosilances | |
| IL191052A0 (en) | Process for the preparation of tamsulosin and related compounds | |
| PL1937626T3 (pl) | Sposób i związki do otrzymywania salmeterolu | |
| SI1902010T1 (sl) | Postopek za pripravo adapalena in odvisnih spojin | |
| TWI365869B (en) | Process for the preparation of phenol | |
| HUP0401379A3 (en) | Process for the preparation of risperidon | |
| HU0500940D0 (en) | Process for the preparation of carbidopa | |
| IL178960A0 (en) | Process for the preparation of pyridin-2-ylmethylsulphinyl-1h-benzimidazol compounds | |
| GB0523637D0 (en) | Process and compounds | |
| ZA200706203B (en) | Processes and compounds for the preparation of substituted naphthylindole derivatives | |
| HUP0500570A3 (en) | Process for the preparation of (s)-(-)-amlodipine | |
| HU0500126D0 (en) | New compounds and process for their preparation | |
| SI1732916T1 (sl) | Postopek za pripravo alkoksikarbonilmetoksi-ciklopentanov | |
| SI1879869T1 (sl) | Postopek za pripravo prekurzorjev 5-alkiltioalkilamino-1-fenil-pirazolov |