ATE535506T1 - Verfahren zur vorbereitung von adapelen und ähnlichen verbindungen - Google Patents

Verfahren zur vorbereitung von adapelen und ähnlichen verbindungen

Info

Publication number
ATE535506T1
ATE535506T1 AT06848698T AT06848698T ATE535506T1 AT E535506 T1 ATE535506 T1 AT E535506T1 AT 06848698 T AT06848698 T AT 06848698T AT 06848698 T AT06848698 T AT 06848698T AT E535506 T1 ATE535506 T1 AT E535506T1
Authority
AT
Austria
Prior art keywords
adapelen
preparing
similar compounds
compounds
similar
Prior art date
Application number
AT06848698T
Other languages
English (en)
Inventor
Serrano Jordi Puig
Original Assignee
Medichem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medichem Sa filed Critical Medichem Sa
Application granted granted Critical
Publication of ATE535506T1 publication Critical patent/ATE535506T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • C07C65/24Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
    • C07C65/26Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic containing rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/02Preparation of carboxylic acids or their salts, halides or anhydrides from salts of carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41Preparation of salts of carboxylic acids
    • C07C51/412Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42Separation; Purification; Stabilisation; Use of additives
    • C07C51/43Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42Separation; Purification; Stabilisation; Use of additives
    • C07C51/47Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42Separation; Purification; Stabilisation; Use of additives
    • C07C51/50Use of additives, e.g. for stabilisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/30Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/56Ring systems containing bridged rings
    • C07C2603/58Ring systems containing bridged rings containing three rings
    • C07C2603/70Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C07C2603/74Adamantanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
AT06848698T 2005-06-17 2006-06-16 Verfahren zur vorbereitung von adapelen und ähnlichen verbindungen ATE535506T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69125905P 2005-06-17 2005-06-17
PCT/IB2006/003987 WO2007072217A2 (en) 2005-06-17 2006-06-16 Process for the preparation of adapalene and related compounds

Publications (1)

Publication Number Publication Date
ATE535506T1 true ATE535506T1 (de) 2011-12-15

Family

ID=38189034

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06848698T ATE535506T1 (de) 2005-06-17 2006-06-16 Verfahren zur vorbereitung von adapelen und ähnlichen verbindungen

Country Status (9)

Country Link
US (3) US8119834B2 (de)
EP (1) EP1902010B1 (de)
AR (1) AR058009A1 (de)
AT (1) ATE535506T1 (de)
CA (1) CA2612497C (de)
ES (1) ES2378085T3 (de)
PL (1) PL1902010T3 (de)
SI (1) SI1902010T1 (de)
WO (1) WO2007072217A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2378085T3 (es) * 2005-06-17 2012-04-04 Medichem, S.A. Procedimiento para la preparación de adapaleno y compuestos relacionados
WO2007125542A2 (en) * 2006-05-03 2007-11-08 Usv Limited A process for preparation of adapalene
CN112479867B (zh) * 2020-12-30 2024-03-29 武汉诺安药业有限公司 一种阿达帕林微粉化的化学制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU85849A1 (fr) * 1985-04-11 1986-11-05 Cird Derives benzonaphtaleniques,leur procede de preparation et leur application dans les domaines pharmaceutiques et cosmetiques
FR2636061B1 (fr) * 1988-09-07 1990-11-09 Cird Procede de preparation de derives de l'adamantane-1
ATE432072T1 (de) * 2002-03-12 2009-06-15 Galderma Res & Dev Verwendung von adapalen zur behandlung dermatologischer erkrankungen
JP5155148B2 (ja) * 2005-04-08 2013-02-27 ガルデルマ・リサーチ・アンド・デヴェロップメント 6−[3−(1−アダマンチル)−4−メトキシフェニル]−2−ナフトエ酸の合成方法
ES2378085T3 (es) * 2005-06-17 2012-04-04 Medichem, S.A. Procedimiento para la preparación de adapaleno y compuestos relacionados

Also Published As

Publication number Publication date
WO2007072217A2 (en) 2007-06-28
US8119834B2 (en) 2012-02-21
EP1902010A2 (de) 2008-03-26
WO2007072217A3 (en) 2007-11-01
ES2378085T3 (es) 2012-04-04
CA2612497C (en) 2015-10-06
EP1902010B1 (de) 2011-11-30
PL1902010T3 (pl) 2012-04-30
SI1902010T1 (sl) 2012-07-31
CA2612497A1 (en) 2007-06-28
US20090131713A1 (en) 2009-05-21
US20150141696A1 (en) 2015-05-21
US20130030214A1 (en) 2013-01-31
AR058009A1 (es) 2008-01-23
US8871972B2 (en) 2014-10-28

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