PL1615879T3 - Sposób wytwarzania kwasu 9-cis-retinowego - Google Patents
Sposób wytwarzania kwasu 9-cis-retinowegoInfo
- Publication number
- PL1615879T3 PL1615879T3 PL04725312T PL04725312T PL1615879T3 PL 1615879 T3 PL1615879 T3 PL 1615879T3 PL 04725312 T PL04725312 T PL 04725312T PL 04725312 T PL04725312 T PL 04725312T PL 1615879 T3 PL1615879 T3 PL 1615879T3
- Authority
- PL
- Poland
- Prior art keywords
- production
- retinoic acid
- cis retinoic
- cis
- acid
- Prior art date
Links
- SHGAZHPCJJPHSC-ZVCIMWCZSA-N 9-cis-retinoic acid Chemical compound OC(=O)/C=C(\C)/C=C/C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-ZVCIMWCZSA-N 0.000 title 1
- 229960001445 alitretinoin Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/203—Retinoic acids ; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/09—Geometrical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03008020 | 2003-04-11 | ||
| PCT/EP2004/003493 WO2004089887A1 (en) | 2003-04-11 | 2004-04-02 | Process for the production of 9-cis retinoic acid |
| EP04725312.5A EP1615879B1 (en) | 2003-04-11 | 2004-04-02 | Process for the production of 9-cis retinoic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1615879T3 true PL1615879T3 (pl) | 2015-02-27 |
Family
ID=33155124
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL04725312T PL1615879T3 (pl) | 2003-04-11 | 2004-04-02 | Sposób wytwarzania kwasu 9-cis-retinowego |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7015353B2 (pl) |
| EP (1) | EP1615879B1 (pl) |
| JP (1) | JP4563997B2 (pl) |
| KR (1) | KR100743278B1 (pl) |
| CN (1) | CN1323071C (pl) |
| CA (1) | CA2520018C (pl) |
| ES (1) | ES2449494T3 (pl) |
| IL (1) | IL170829A (pl) |
| MX (1) | MXPA05010771A (pl) |
| PL (1) | PL1615879T3 (pl) |
| TW (1) | TWI293951B (pl) |
| WO (1) | WO2004089887A1 (pl) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2665909C (en) * | 2006-09-27 | 2015-06-09 | Dsm Fine Chemicals Austria Nfg Gmbh & Co Kg. | Improved method of production of 9-cis-retinoic acid |
| CN103153936B (zh) * | 2010-10-01 | 2016-08-03 | 帝斯曼知识产权资产管理有限公司 | 改进的培瑞维a酸的合成 |
| CN102775338B (zh) * | 2011-05-13 | 2016-09-21 | 重庆华邦胜凯制药有限公司 | 全反式维甲酸合成方法 |
| US9221854B2 (en) | 2012-08-17 | 2015-12-29 | Basf Se | Isomerization of olefinic compounds |
| EP2885309B1 (de) | 2012-08-17 | 2017-03-15 | Basf Se | Isomerisierung olefinischer verbindungen |
| KR102420818B1 (ko) | 2021-11-29 | 2022-07-14 | (주)아크에이르 | All-trans에서 9-cis Retinoic acid로의 광 이성질화 전환 반응 장치 및 이를 이용한 이성질체 전환방법 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1068710B (de) * | 1958-08-06 | 1959-11-12 | Badische Anilin- &. Soda-Fabrik Aktiengesellschaft, Ludwigshafen/Rhein | Verfahren zur Herstellung von Verbindungen der beta-Ionylidenäthyliden-Reihe |
| DE4344148A1 (de) * | 1993-12-23 | 1995-08-24 | Basf Ag | Verfahren zur Herstellung von 9-(Z)-Retinsäure |
| EP0908179A1 (en) | 1997-08-23 | 1999-04-14 | Werner Bollag | Treatment of cell-mediated immune diseases |
-
2004
- 2004-04-02 JP JP2006504958A patent/JP4563997B2/ja not_active Expired - Lifetime
- 2004-04-02 KR KR1020057019224A patent/KR100743278B1/ko not_active Expired - Lifetime
- 2004-04-02 EP EP04725312.5A patent/EP1615879B1/en not_active Expired - Lifetime
- 2004-04-02 MX MXPA05010771A patent/MXPA05010771A/es active IP Right Grant
- 2004-04-02 WO PCT/EP2004/003493 patent/WO2004089887A1/en not_active Ceased
- 2004-04-02 CN CNB2004800095877A patent/CN1323071C/zh not_active Expired - Lifetime
- 2004-04-02 ES ES04725312.5T patent/ES2449494T3/es not_active Expired - Lifetime
- 2004-04-02 CA CA2520018A patent/CA2520018C/en not_active Expired - Lifetime
- 2004-04-02 PL PL04725312T patent/PL1615879T3/pl unknown
- 2004-04-06 TW TW093109532A patent/TWI293951B/zh not_active IP Right Cessation
- 2004-04-07 US US10/819,693 patent/US7015353B2/en not_active Expired - Lifetime
-
2005
- 2005-09-13 IL IL170829A patent/IL170829A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| CN1771227A (zh) | 2006-05-10 |
| EP1615879A1 (en) | 2006-01-18 |
| KR100743278B1 (ko) | 2007-07-26 |
| US7015353B2 (en) | 2006-03-21 |
| US20040235951A1 (en) | 2004-11-25 |
| MXPA05010771A (es) | 2005-12-12 |
| JP4563997B2 (ja) | 2010-10-20 |
| EP1615879B1 (en) | 2014-01-29 |
| CA2520018A1 (en) | 2004-10-21 |
| CA2520018C (en) | 2011-01-04 |
| CN1323071C (zh) | 2007-06-27 |
| ES2449494T3 (es) | 2014-03-20 |
| TWI293951B (en) | 2008-03-01 |
| TW200510295A (en) | 2005-03-16 |
| JP2006522757A (ja) | 2006-10-05 |
| IL170829A (en) | 2011-12-29 |
| KR20050121258A (ko) | 2005-12-26 |
| WO2004089887A1 (en) | 2004-10-21 |
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