PL1603918T3 - Metaloftalocyjaniny zawierające bor, sposób ich wytwarzania, zawierające je środki farmaceutyczne ich zastosowanie - Google Patents

Metaloftalocyjaniny zawierające bor, sposób ich wytwarzania, zawierające je środki farmaceutyczne ich zastosowanie

Info

Publication number
PL1603918T3
PL1603918T3 PL04719429T PL04719429T PL1603918T3 PL 1603918 T3 PL1603918 T3 PL 1603918T3 PL 04719429 T PL04719429 T PL 04719429T PL 04719429 T PL04719429 T PL 04719429T PL 1603918 T3 PL1603918 T3 PL 1603918T3
Authority
PL
Poland
Prior art keywords
preparation
pharmaceutical compositions
phthalocyanines
meta
boronated
Prior art date
Application number
PL04719429T
Other languages
English (en)
Inventor
Gabrio Roncucci
Giulio Jori
Francesca Giuntini
Clara Fabris
Giacomo Chiti
Moira Municchi
Donata Dei
Original Assignee
Molteni Therapeutics S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Molteni Therapeutics S R L filed Critical Molteni Therapeutics S R L
Publication of PL1603918T3 publication Critical patent/PL1603918T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/009—Neutron capture therapy, e.g. using uranium or non-boron material
    • A61K41/0095—Boron neutron capture therapy, i.e. BNCT, e.g. using boronated porphyrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/16—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C317/18—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/022—Boron compounds without C-boron linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/06—Aluminium compounds
    • C07F5/069—Aluminium compounds without C-aluminium linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/025—Silicon compounds without C-silicon linkages
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B47/00—Porphines; Azaporphines
    • C09B47/04—Phthalocyanines abbreviation: Pc
    • C09B47/045—Special non-pigmentary uses, e.g. catalyst, photosensitisers of phthalocyanine dyes or pigments
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B47/00—Porphines; Azaporphines
    • C09B47/04—Phthalocyanines abbreviation: Pc
    • C09B47/06—Preparation from carboxylic acids or derivatives thereof, e.g. anhydrides, amides, mononitriles, phthalimide, o-cyanobenzamide
    • C09B47/067—Preparation from carboxylic acids or derivatives thereof, e.g. anhydrides, amides, mononitriles, phthalimide, o-cyanobenzamide from phthalodinitriles naphthalenedinitriles, aromatic dinitriles prepared in situ, hydrogenated phthalodinitrile
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B47/00—Porphines; Azaporphines
    • C09B47/04—Phthalocyanines abbreviation: Pc
    • C09B47/08—Preparation from other phthalocyanine compounds, e.g. cobaltphthalocyanineamine complex
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL04719429T 2003-03-11 2004-03-11 Metaloftalocyjaniny zawierające bor, sposób ich wytwarzania, zawierające je środki farmaceutyczne ich zastosowanie PL1603918T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT000063A ITFI20030063A1 (it) 2003-03-11 2003-03-11 Metallo ftalocianine boronate, loro preparazione, composizioni
EP04719429A EP1603918B1 (en) 2003-03-11 2004-03-11 Boronated metal-phthalocyanines, process for their preparation, pharmaceutical compositions comprising them and use thereof
PCT/EP2004/002505 WO2004081014A1 (en) 2003-03-11 2004-03-11 Boronated metal-phthalocyanines, process for their preparation, pharmaceutical compositions comprising them and use thereof

Publications (1)

Publication Number Publication Date
PL1603918T3 true PL1603918T3 (pl) 2009-01-30

Family

ID=32983184

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04719429T PL1603918T3 (pl) 2003-03-11 2004-03-11 Metaloftalocyjaniny zawierające bor, sposób ich wytwarzania, zawierające je środki farmaceutyczne ich zastosowanie

Country Status (15)

Country Link
US (1) US7842682B2 (pl)
EP (1) EP1603918B1 (pl)
JP (1) JP4968673B2 (pl)
CN (1) CN100374442C (pl)
AT (1) ATE402936T1 (pl)
AU (1) AU2004220406B2 (pl)
CA (1) CA2518934C (pl)
DE (1) DE602004015428D1 (pl)
DK (1) DK1603918T3 (pl)
ES (1) ES2311147T3 (pl)
IL (1) IL170761A (pl)
IT (1) ITFI20030063A1 (pl)
PL (1) PL1603918T3 (pl)
WO (1) WO2004081014A1 (pl)
ZA (1) ZA200507975B (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7910755B2 (en) * 2004-09-29 2011-03-22 Harbor Biosciences, Inc. Stem cell expansion and uses
WO2007098968A1 (en) * 2006-03-03 2007-09-07 Universität Bremen Triggered release of liposome contents
US8287839B2 (en) * 2006-12-04 2012-10-16 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
CN102284059A (zh) * 2011-08-23 2011-12-21 福州大学 一种光敏剂及其制备方法和应用
US10723694B2 (en) 2018-10-02 2020-07-28 Kuwait University Propargyl-functionalized macrocyclic compounds
CN116731315B (zh) * 2022-03-04 2024-06-21 中国科学院化学研究所 一种含硼邻苯二甲腈树脂及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3730950A (en) * 1972-02-01 1973-05-01 Singer Co Polyurethane copolymers derived from the carborane-silicon phthalocyanine monomer
JPH08225751A (ja) * 1994-10-26 1996-09-03 Nippon Shokubai Co Ltd 新規フタロシアニン化合物、その製造方法およびそれらを用いた光記録媒体
IT1294325B1 (it) * 1997-08-14 1999-03-24 Molteni L E C Dei Fratelli Ali Zinco-ftalocianine e relativi coniugati, preparazione e uso nella terapia fotodinamica e come diagnostici

Also Published As

Publication number Publication date
ES2311147T3 (es) 2009-02-01
CN100374442C (zh) 2008-03-12
US7842682B2 (en) 2010-11-30
ITFI20030063A1 (it) 2004-09-12
EP1603918B1 (en) 2008-07-30
CA2518934A1 (en) 2004-09-23
AU2004220406A1 (en) 2004-09-23
EP1603918A1 (en) 2005-12-14
WO2004081014A1 (en) 2004-09-23
ZA200507975B (en) 2006-12-27
AU2004220406B2 (en) 2010-03-04
US20060135478A1 (en) 2006-06-22
JP2006519810A (ja) 2006-08-31
US20080009464A9 (en) 2008-01-10
CA2518934C (en) 2012-07-03
DE602004015428D1 (de) 2008-09-11
CN1788009A (zh) 2006-06-14
ATE402936T1 (de) 2008-08-15
DK1603918T3 (da) 2008-11-17
JP4968673B2 (ja) 2012-07-04
IL170761A (en) 2012-03-29

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