PH22010A - Antiprotozoal combinations of naphthoquinones and pyridinols - Google Patents
Antiprotozoal combinations of naphthoquinones and pyridinolsInfo
- Publication number
- PH22010A PH22010A PH30544A PH30544A PH22010A PH 22010 A PH22010 A PH 22010A PH 30544 A PH30544 A PH 30544A PH 30544 A PH30544 A PH 30544A PH 22010 A PH22010 A PH 22010A
- Authority
- PH
- Philippines
- Prior art keywords
- antiprotozoal
- combinations
- pyridinols
- naphthoquinones
- combination
- Prior art date
Links
- 230000000842 anti-protozoal effect Effects 0.000 title abstract 3
- 229930192627 Naphthoquinone Natural products 0.000 title abstract 2
- 239000003904 antiprotozoal agent Substances 0.000 title abstract 2
- 150000002791 naphthoquinones Chemical class 0.000 title abstract 2
- UBQKCCHYAOITMY-UHFFFAOYSA-N pyridin-2-ol Chemical class OC1=CC=CC=N1 UBQKCCHYAOITMY-UHFFFAOYSA-N 0.000 title 1
- GCNTZFIIOFTKIY-UHFFFAOYSA-N 4-hydroxypyridine Chemical compound OC1=CC=NC=C1 GCNTZFIIOFTKIY-UHFFFAOYSA-N 0.000 abstract 1
- 230000000875 corresponding effect Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 201000004792 malaria Diseases 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Steroid Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Medicinal Preparation (AREA)
- Laminated Bodies (AREA)
- Cosmetics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB838310140A GB8310140D0 (en) | 1983-04-14 | 1983-04-14 | Antiprotozoal agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH22010A true PH22010A (en) | 1988-05-02 |
Family
ID=10541104
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH30544A PH22010A (en) | 1983-04-14 | 1984-04-13 | Antiprotozoal combinations of naphthoquinones and pyridinols |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5053418A (enEXAMPLES) |
| EP (2) | EP0123239B1 (enEXAMPLES) |
| JP (1) | JPS59205316A (enEXAMPLES) |
| AT (2) | ATE91892T1 (enEXAMPLES) |
| AU (1) | AU574354B2 (enEXAMPLES) |
| CY (1) | CY1862A (enEXAMPLES) |
| DE (2) | DE3486189T2 (enEXAMPLES) |
| GB (1) | GB8310140D0 (enEXAMPLES) |
| HK (1) | HK129695A (enEXAMPLES) |
| IL (1) | IL71546A (enEXAMPLES) |
| PH (1) | PH22010A (enEXAMPLES) |
| UY (1) | UY24036A1 (enEXAMPLES) |
| ZA (1) | ZA842796B (enEXAMPLES) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8500292D0 (en) * | 1985-01-07 | 1985-02-13 | Wellcome Found | Treatment of babesiosis |
| US5206268A (en) * | 1988-08-16 | 1993-04-27 | Burroughs Wellcome Co. | Medicaments |
| GB8819477D0 (en) * | 1988-08-16 | 1988-09-21 | Wellcome Found | Medicaments |
| US5225184A (en) * | 1988-08-16 | 1993-07-06 | Burroughs Wellcome Co. | Medicaments |
| JP2804302B2 (ja) * | 1988-08-16 | 1998-09-24 | ザ ウエルカム フアウンデーション リミテッド | 治療剤 |
| EP0567162A1 (en) * | 1989-09-22 | 1993-10-27 | The Wellcome Foundation Limited | Medicaments for the treatment of toxoplasmosis |
| GB8921516D0 (en) * | 1989-09-22 | 1989-11-08 | Wellcome Found | Medicaments |
| GB8923254D0 (en) * | 1989-10-16 | 1989-12-06 | Wellcome Found | Medicaments |
| US5403934A (en) * | 1990-03-12 | 1995-04-04 | Burroughs Wellcome Co. | Heterocyclic compounds |
| GB9005518D0 (en) * | 1990-03-12 | 1990-05-09 | Wellcome Found | Heterocyclic compounds |
| GB9126874D0 (en) * | 1991-12-18 | 1992-02-19 | Wellcome Found | Medicaments |
| GB9216859D0 (en) * | 1992-08-07 | 1992-09-23 | Wellcome Found | Medicaments |
| GB9224739D0 (en) | 1992-11-26 | 1993-01-13 | Wellcome Found | Medicaments |
| GB9226905D0 (en) | 1992-12-24 | 1993-02-17 | Wellcome Found | Pharmaceutical preparation |
| FR2707495B1 (fr) * | 1993-07-02 | 1995-09-01 | Roussel Uclaf | Nouvelle utilisation de dérivés de la béta-naphtoquinone ainsi que de leurs sels. |
| GB9410299D0 (en) * | 1994-05-20 | 1994-07-13 | British Tech Group | Naphthoquinone derivatives |
| US5684035A (en) * | 1996-07-17 | 1997-11-04 | Kapadia; Govind J. | Antimalarial agents |
| US20080254136A1 (en) * | 2004-07-30 | 2008-10-16 | Japan Health Sciences Foundation | Antiprotozoal Agent |
| EP2246329A1 (en) | 2009-01-19 | 2010-11-03 | Glaxo Group Limited | 4(1H)-pyridinone derivatives and their use as antimalaria agents |
| WO2010081904A1 (en) | 2009-01-19 | 2010-07-22 | Glaxo Group Limited | 4 ( 1h) -pyridinone derivatives and their use as antimalaria agents |
| EP2408467A2 (en) * | 2009-03-20 | 2012-01-25 | University Of South Florida | A method and composition using a dual specificity protein tyrosine phosphatase as an antimalarial drug target |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2553647A (en) * | 1946-03-20 | 1951-05-22 | Research Corp | Naphthoquinone antimalarials |
| US2553648A (en) | 1948-01-08 | 1951-05-22 | Research Corp | Naphthoquinone compounds |
| NL124395C (enEXAMPLES) | 1963-09-25 | |||
| US3347742A (en) | 1965-05-28 | 1967-10-17 | Merck & Co Inc | 2-(4-cyclohexylcyclohexyl)-3-hydroxy-1, 4-naphthoquinone in controlling coccidiosis in poultry |
| US3367830A (en) | 1965-06-23 | 1968-02-06 | Merck & Co Inc | Controlling coccidiosis in poultry with 1,4-naphthoquinones |
| AU458235B2 (en) * | 1971-02-09 | 1975-02-20 | Shionogi & Co., Ltd | Quinone derivatives and compositions containing thesame |
| FI762480A7 (enEXAMPLES) | 1975-09-15 | 1977-03-16 | Du Pont | |
| GB1553424A (en) | 1976-02-10 | 1979-09-26 | Wellcome Found | Method of treating protozal diseases |
| ZA786551B (en) | 1977-11-22 | 1980-07-30 | Wellcome Found | Antitheilerial naphthoquinone derivatives |
| US4485116A (en) | 1981-10-16 | 1984-11-27 | Hudson Alan T | Antiprotozoal compounds |
| US4485117A (en) * | 1981-10-16 | 1984-11-27 | Hudson Alan T | Antiprotozoal compounds |
| GB8310141D0 (en) * | 1983-04-14 | 1983-05-18 | Wellcome Found | Naphthoquinone derivatives |
-
1983
- 1983-04-14 GB GB838310140A patent/GB8310140D0/en active Pending
-
1984
- 1984-04-13 ZA ZA842796A patent/ZA842796B/xx unknown
- 1984-04-13 IL IL71546A patent/IL71546A/xx not_active IP Right Cessation
- 1984-04-13 PH PH30544A patent/PH22010A/en unknown
- 1984-04-13 AU AU26797/84A patent/AU574354B2/en not_active Ceased
- 1984-04-14 EP EP84104249A patent/EP0123239B1/en not_active Expired - Lifetime
- 1984-04-14 AT AT90114375T patent/ATE91892T1/de active
- 1984-04-14 EP EP90114375A patent/EP0401875B1/en not_active Expired - Lifetime
- 1984-04-14 DE DE90114375T patent/DE3486189T2/de not_active Expired - Lifetime
- 1984-04-14 DE DE8484104249T patent/DE3485033D1/de not_active Expired - Lifetime
- 1984-04-14 JP JP59075673A patent/JPS59205316A/ja active Granted
- 1984-04-14 AT AT84104249T patent/ATE67089T1/de active
-
1989
- 1989-12-11 US US07/449,485 patent/US5053418A/en not_active Expired - Lifetime
-
1995
- 1995-08-17 HK HK129695A patent/HK129695A/en not_active IP Right Cessation
- 1995-09-13 UY UY24036A patent/UY24036A1/es not_active IP Right Cessation
-
1996
- 1996-04-05 CY CY186296A patent/CY1862A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2679784A (en) | 1984-10-18 |
| EP0401875B1 (en) | 1993-07-28 |
| EP0123239A3 (en) | 1987-11-25 |
| ZA842796B (en) | 1985-11-27 |
| EP0401875A3 (en) | 1990-12-27 |
| AU574354B2 (en) | 1988-07-07 |
| DE3485033D1 (de) | 1991-10-17 |
| JPH0481568B2 (enEXAMPLES) | 1992-12-24 |
| US5053418A (en) | 1991-10-01 |
| GB8310140D0 (en) | 1983-05-18 |
| EP0123239A2 (en) | 1984-10-31 |
| DE3486189D1 (de) | 1993-09-02 |
| EP0401875A2 (en) | 1990-12-12 |
| IL71546A (en) | 1987-08-31 |
| DE3486189T2 (de) | 1994-03-03 |
| ATE91892T1 (de) | 1993-08-15 |
| EP0123239B1 (en) | 1991-09-11 |
| ATE67089T1 (de) | 1991-09-15 |
| UY24036A1 (es) | 1995-09-18 |
| IL71546A0 (en) | 1984-07-31 |
| HK129695A (en) | 1995-08-24 |
| CY1862A (en) | 1996-04-05 |
| JPS59205316A (ja) | 1984-11-20 |
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