PH21394A - New conjugates of vinblastine, a process for their preparation and their use in therapy - Google Patents

New conjugates of vinblastine, a process for their preparation and their use in therapy

Info

Publication number
PH21394A
PH21394A PH30778A PH30778A PH21394A PH 21394 A PH21394 A PH 21394A PH 30778 A PH30778 A PH 30778A PH 30778 A PH30778 A PH 30778A PH 21394 A PH21394 A PH 21394A
Authority
PH
Philippines
Prior art keywords
vinblastine
therapy
preparation
new conjugates
conjugates
Prior art date
Application number
PH30778A
Inventor
Trouet Andre Benoit Leon
Rao Kandukuri Sivapras Bushana
Hannart Jean Alfred Alphonse
Dejonghe Jean-Paul
Original Assignee
Omnichem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omnichem Sa filed Critical Omnichem Sa
Publication of PH21394A publication Critical patent/PH21394A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6805—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a vinca alkaloid
PH30778A 1983-12-29 1984-06-06 New conjugates of vinblastine, a process for their preparation and their use in therapy PH21394A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU85161A LU85161A1 (en) 1983-12-29 1983-12-29 NOVEL VINBLASTIN CONJUGATES, THEIR PREPARATION PROCESS AND THEIR THERAPEUTIC USE

Publications (1)

Publication Number Publication Date
PH21394A true PH21394A (en) 1987-10-15

Family

ID=19730204

Family Applications (1)

Application Number Title Priority Date Filing Date
PH30778A PH21394A (en) 1983-12-29 1984-06-06 New conjugates of vinblastine, a process for their preparation and their use in therapy

Country Status (4)

Country Link
DD (1) DD219771A5 (en)
IL (1) IL71642A (en)
LU (1) LU85161A1 (en)
PH (1) PH21394A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2609934A1 (en) 2007-02-16 2013-07-03 KTB Tumorforschungsgesellschaft mbH Receptor And Antigen Targeted Prodrug

Also Published As

Publication number Publication date
LU85161A1 (en) 1985-09-12
DD219771A5 (en) 1985-03-13
IL71642A (en) 1990-11-05

Similar Documents

Publication Publication Date Title
ZA842402B (en) New substituted 3 hydroxyflavones,a method for their preparation and their use in therapy
DE3760201D1 (en) (-)-benzhydrylsulfinylacetamide, process for its preparation and its use in therapy
DE3372769D1 (en) 3-aminoquinuclidin derivatives, process for their preparation and their use as therapeutical agents
PT79917B (en) Process for preparing new renin- inhibotory peptides and their use
DE3160480D1 (en) Pyridoxine derivatives, process for their preparation and their therapeutical use
PT77204A (en) Process for preparing perfluorocarbon emulsions and their preparation and use in therapy
DE3165788D1 (en) Thienopyridinone derivatives, process for their preparation and their therapeutical use
PH21087A (en) Dibenzodiazepin derivatives and process for their preparation
DE3479158D1 (en) Diagnostic agent, a process for its preparation and its use in diagnostic methods
DE3463041D1 (en) Tributylphenolether-glycidyl-sulphonates, process for their preparation and their use
DE3479494D1 (en) Prostacyclines and process for their preparation
DE3362189D1 (en) 14-amino-steroid derivatives, process for their preparation and their use in therapy
ZA861307B (en) New cephalosporins,a process for their preparation,and their use in medicaments
EP0121081A3 (en) Azolylmethylcycloalkanes, process for their preparation and their therapeutical use
ZA821823B (en) 4-fluoro-3-phenoxy-benzyl 3-alken-1-yl-2,2-dimethyl-cyclopro-panecarboxylates, a process for their preparation and their use in pest-combating agents
ZA846580B (en) 16-fluoro-16,17-didehydro-prostanoids and process for their preparation
DE3367598D1 (en) 14-amino-steroid derivatives, their therapeutical use and process for their preparation
PT81534A (en) Process for preparing benzamides and their salts
ZA843093B (en) New conjugates of vinblastine,a process for their preparation and their use in therapy
PH21394A (en) New conjugates of vinblastine, a process for their preparation and their use in therapy
EP0136945A3 (en) Cinnamoyl compounds, process for their preparation and their therapeutical use
IL70361A0 (en) 3'5'-diarabinosides,their preparation and their application in therapy
ZA905464B (en) Anti-infective agents,process for their preparation and their use in therapy
AR241906A1 (en) Benzamides, process for their preparation and their therapeutical use
ZA858249B (en) 1,4-dihydropyridine-hydroxyamines,a process for their preparation and their use in medicaments