IL71642A - Galactosylated human albumin conjugates of vinblastine derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Galactosylated human albumin conjugates of vinblastine derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL71642A
IL71642A IL71642A IL7164284A IL71642A IL 71642 A IL71642 A IL 71642A IL 71642 A IL71642 A IL 71642A IL 7164284 A IL7164284 A IL 7164284A IL 71642 A IL71642 A IL 71642A
Authority
IL
Israel
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
human albumin
albumin conjugates
Prior art date
Application number
IL71642A
Original Assignee
Omnichem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omnichem Sa filed Critical Omnichem Sa
Priority to IL80279A priority Critical patent/IL80279A0/en
Publication of IL71642A publication Critical patent/IL71642A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6805—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a vinca alkaloid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL71642A 1983-12-29 1984-04-25 Galactosylated human albumin conjugates of vinblastine derivatives,their preparation and pharmaceutical compositions containing them IL71642A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL80279A IL80279A0 (en) 1984-04-25 1986-10-10 New conjugates of vinblastine and its derivatives,a process for their preparation and pharmaceutical compositions containing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU85161A LU85161A1 (en) 1983-12-29 1983-12-29 NOVEL VINBLASTIN CONJUGATES, THEIR PREPARATION PROCESS AND THEIR THERAPEUTIC USE

Publications (1)

Publication Number Publication Date
IL71642A true IL71642A (en) 1990-11-05

Family

ID=19730204

Family Applications (1)

Application Number Title Priority Date Filing Date
IL71642A IL71642A (en) 1983-12-29 1984-04-25 Galactosylated human albumin conjugates of vinblastine derivatives,their preparation and pharmaceutical compositions containing them

Country Status (4)

Country Link
DD (1) DD219771A5 (en)
IL (1) IL71642A (en)
LU (1) LU85161A1 (en)
PH (1) PH21394A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2606911A1 (en) * 2007-02-16 2013-06-26 KTB Tumorforschungsgesellschaft mbH Receptor And Antigen Targeted Prodrug

Also Published As

Publication number Publication date
LU85161A1 (en) 1985-09-12
PH21394A (en) 1987-10-15
DD219771A5 (en) 1985-03-13

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IL71642A (en) Galactosylated human albumin conjugates of vinblastine derivatives,their preparation and pharmaceutical compositions containing them