PH21295A - Octahydroindolizine compounds useful as analgesics - Google Patents

Octahydroindolizine compounds useful as analgesics

Info

Publication number
PH21295A
PH21295A PH33265A PH33265A PH21295A PH 21295 A PH21295 A PH 21295A PH 33265 A PH33265 A PH 33265A PH 33265 A PH33265 A PH 33265A PH 21295 A PH21295 A PH 21295A
Authority
PH
Philippines
Prior art keywords
analgesics
compounds useful
octahydroindolizine
octahydroindolizine compounds
synthesis
Prior art date
Application number
PH33265A
Other languages
English (en)
Inventor
Carmosin Richard Joel
Carson John Robert
Original Assignee
Mcneilab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneilab Inc filed Critical Mcneilab Inc
Publication of PH21295A publication Critical patent/PH21295A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Seasonings (AREA)
  • Plural Heterocyclic Compounds (AREA)
PH33265A 1985-01-09 1986-01-08 Octahydroindolizine compounds useful as analgesics PH21295A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/689,883 US4582836A (en) 1985-01-09 1985-01-09 Octahydroindolizine compounds useful as analgesics

Publications (1)

Publication Number Publication Date
PH21295A true PH21295A (en) 1987-09-28

Family

ID=24770255

Family Applications (1)

Application Number Title Priority Date Filing Date
PH33265A PH21295A (en) 1985-01-09 1986-01-08 Octahydroindolizine compounds useful as analgesics

Country Status (16)

Country Link
US (1) US4582836A (es)
EP (1) EP0187711B1 (es)
JP (1) JPS61204182A (es)
CN (1) CN86100131A (es)
AT (1) ATE55907T1 (es)
CA (1) CA1255306A (es)
DE (1) DE3673657D1 (es)
DK (1) DK7286A (es)
ES (2) ES8703470A1 (es)
FI (1) FI860074A (es)
GR (1) GR860021B (es)
HU (1) HU195964B (es)
NO (1) NO860048L (es)
NZ (1) NZ214573A (es)
PH (1) PH21295A (es)
ZA (1) ZA86173B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4689329A (en) * 1986-02-04 1987-08-25 Mcneilab, Inc. 5-substituted octahydroindolizine analgesics compounds and 7-keto intermediates
US4716172A (en) * 1986-04-10 1987-12-29 Mcneilab, Inc. 4-substituted octahydroquinolizine analgesic compounds and octahydroquinolizinium intermediates
US4683239A (en) * 1986-04-10 1987-07-28 Mcneilab, Inc. 3-diphenyl substituted octahydroindolizine analgesic compounds
US4800207A (en) * 1987-11-02 1989-01-24 Mcneilab, Inc. Hexahydropyrrolizine compounds useful as analgesics
ZA917371B (en) * 1990-09-20 1992-06-24 Merrell Dow Pharma Calcium uptake inhibitors
US5733912A (en) * 1997-02-19 1998-03-31 Abbott Laboratories 7A-heterocycle substituted hexahydro-1H-pyrrolizine compounds useful in controlling chemical synaptic transmission
US10533000B2 (en) 2011-05-26 2020-01-14 Sunovion Pharmaceuticals, Inc. Metabotrophic glutamate receptor 5 modulators and methods of use thereof

Also Published As

Publication number Publication date
DE3673657D1 (de) 1990-10-04
ES553207A0 (es) 1987-08-01
EP0187711A3 (en) 1987-08-12
DK7286D0 (da) 1986-01-08
GR860021B (en) 1986-05-08
ES8703470A1 (es) 1987-02-16
FI860074A0 (fi) 1986-01-08
HUT41025A (en) 1987-03-30
ATE55907T1 (de) 1990-09-15
DK7286A (da) 1986-07-10
EP0187711A2 (en) 1986-07-16
ES550742A0 (es) 1987-02-16
EP0187711B1 (en) 1990-08-29
NO860048L (no) 1986-07-10
JPS61204182A (ja) 1986-09-10
NZ214573A (en) 1988-04-29
CA1255306A (en) 1989-06-06
US4582836A (en) 1986-04-15
CN86100131A (zh) 1986-10-15
HU195964B (en) 1988-08-29
FI860074A (fi) 1986-07-10
ZA86173B (en) 1987-08-26
ES8707530A1 (es) 1987-08-01

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