PH18087A - Novel anthracycline derivative and pharmaceutical composition comprising said compound - Google Patents
Novel anthracycline derivative and pharmaceutical composition comprising said compoundInfo
- Publication number
- PH18087A PH18087A PH26235A PH26235A PH18087A PH 18087 A PH18087 A PH 18087A PH 26235 A PH26235 A PH 26235A PH 26235 A PH26235 A PH 26235A PH 18087 A PH18087 A PH 18087A
- Authority
- PH
- Philippines
- Prior art keywords
- compound
- pharmaceutical composition
- anthracycline derivative
- novel anthracycline
- novel
- Prior art date
Links
- 229940045799 anthracyclines and related substance Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/215—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring having unsaturation outside the six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/26—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydration of carbon-to-carbon triple bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP55130645A JPS5756494A (en) | 1980-09-22 | 1980-09-22 | New anthracyclin derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH18087A true PH18087A (en) | 1985-03-20 |
Family
ID=15039201
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH26235A PH18087A (en) | 1980-09-22 | 1981-09-21 | Novel anthracycline derivative and pharmaceutical composition comprising said compound |
| PH28790A PH18162A (en) | 1980-09-22 | 1983-04-18 | Process for production of 4-demethoxy-7,11-di-deoxy-daunomycinone |
| PH29674A PH18633A (en) | 1980-09-22 | 1983-10-07 | Novel antrancyclinone derivative |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH28790A PH18162A (en) | 1980-09-22 | 1983-04-18 | Process for production of 4-demethoxy-7,11-di-deoxy-daunomycinone |
| PH29674A PH18633A (en) | 1980-09-22 | 1983-10-07 | Novel antrancyclinone derivative |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4355026A (en, 2012) |
| EP (2) | EP0049403B1 (en, 2012) |
| JP (1) | JPS5756494A (en, 2012) |
| AU (1) | AU542707B2 (en, 2012) |
| CA (1) | CA1177070A (en, 2012) |
| DE (1) | DE3163896D1 (en, 2012) |
| DK (1) | DK154419C (en, 2012) |
| ES (2) | ES505656A0 (en, 2012) |
| PH (3) | PH18087A (en, 2012) |
| ZA (1) | ZA816564B (en, 2012) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4411834A (en) * | 1978-02-09 | 1983-10-25 | Farmitalia Carlo Erba, S.P.A. | Preparation of II-deoxy anthracycline antibiotics |
| IT1210476B (it) * | 1981-05-28 | 1989-09-14 | Erba Farmitalia | Antracicline. |
| CA1187434A (en) * | 1981-08-11 | 1985-05-21 | Akihiro Yoshimoto | Anthracycline antibiotics and their preparation method |
| US4563444A (en) * | 1982-05-26 | 1986-01-07 | Farmitalia Carlo Erba S.P.A. | Anthracycline glycosides, use and compositions containing same |
| FR2551057B1 (fr) * | 1983-08-30 | 1986-07-18 | Hoechst Lab | Nouveaux aglycones utiles pour la preparation des antibiotiques et des antitumoraux de la serie des anthracyclines et leurs procedes de preparation |
| GB8426672D0 (en) * | 1984-10-22 | 1984-11-28 | Erba Farmitalia | Pharmaceutical compositions |
| IT1190399B (it) * | 1985-10-04 | 1988-02-16 | Zambon Spa | Processo per la preparazione di composti carbonilici otticamente attivi |
| JPH0372492A (ja) * | 1990-08-04 | 1991-03-27 | Mercian Corp | アントラサイクリン誘導体及びその製造方法 |
| WO1999058543A1 (en) * | 1998-05-13 | 1999-11-18 | Instytut Farmaceutyczny | New n-alkyloxycarbonyl derivatives of monosaccharides l-acosamine and l-daunosamine |
| EP1165578B1 (en) * | 1999-03-19 | 2012-02-22 | Waldemar Priebe | Methods and compositions for the manufacture of c-3' and c-4' anthracycline antibiotics |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1527892A (fr) * | 1967-03-15 | 1968-06-07 | Rhone Poulenc Sa | Nouveau procédé de préparation de l'antibiotique 13057 r.p. |
| YU33730B (en) * | 1967-04-18 | 1978-02-28 | Farmaceutici Italia | Process for preparing a novel antibiotic substance and salts thereof |
| US4020270A (en) * | 1974-05-02 | 1977-04-26 | Societa' Farmaceutici Italia S.P.A. | L-lyxohex-1-enopyranose derivative |
| GB1470860A (en) * | 1974-10-29 | 1977-04-21 | Farmaceutici Italia | Anthracycline glycosides |
| GB1500421A (en) * | 1975-01-22 | 1978-02-08 | Farmaceutici Italia | Optically active anthracyclinones |
| GB1527050A (en) * | 1976-06-19 | 1978-10-04 | Farmaceutici Italia | Optically active anthracyclinones |
| NL7900869A (nl) * | 1978-02-09 | 1979-08-13 | Erba Farmitalia | Anthracyclinenantibiotica. |
| GB2036021B (en) * | 1978-11-21 | 1983-04-13 | Erba Farmitalia | Antitumour antibiotics |
| GB2067552B (en) * | 1980-01-16 | 1984-02-29 | Erba Farmitalia | Anthracyline derivatives |
-
1980
- 1980-09-22 JP JP55130645A patent/JPS5756494A/ja active Granted
-
1981
- 1981-09-11 US US06/300,874 patent/US4355026A/en not_active Expired - Fee Related
- 1981-09-17 EP EP81107374A patent/EP0049403B1/en not_active Expired
- 1981-09-17 EP EP83101145A patent/EP0086430B1/en not_active Expired
- 1981-09-17 DE DE8181107374T patent/DE3163896D1/de not_active Expired
- 1981-09-21 CA CA000386277A patent/CA1177070A/en not_active Expired
- 1981-09-21 DK DK418581A patent/DK154419C/da not_active IP Right Cessation
- 1981-09-21 PH PH26235A patent/PH18087A/en unknown
- 1981-09-21 AU AU75532/81A patent/AU542707B2/en not_active Ceased
- 1981-09-21 ES ES505656A patent/ES505656A0/es active Granted
- 1981-09-22 ZA ZA816564A patent/ZA816564B/xx unknown
-
1982
- 1982-08-11 ES ES514919A patent/ES514919A0/es active Granted
-
1983
- 1983-04-18 PH PH28790A patent/PH18162A/en unknown
- 1983-10-07 PH PH29674A patent/PH18633A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU7553281A (en) | 1982-04-01 |
| JPS5756494A (en) | 1982-04-05 |
| ES8302733A1 (es) | 1982-12-01 |
| DE3163896D1 (en) | 1984-07-05 |
| US4355026A (en) | 1982-10-19 |
| PH18162A (en) | 1985-04-03 |
| AU542707B2 (en) | 1985-03-07 |
| PH18633A (en) | 1985-08-23 |
| DK418581A (da) | 1982-03-23 |
| DK154419B (da) | 1988-11-14 |
| ES8306765A1 (es) | 1983-06-01 |
| CA1177070A (en) | 1984-10-30 |
| EP0049403A2 (en) | 1982-04-14 |
| ES514919A0 (es) | 1983-06-01 |
| EP0086430A1 (en) | 1983-08-24 |
| JPS6121559B2 (en, 2012) | 1986-05-27 |
| EP0086430B1 (en) | 1985-11-06 |
| ES505656A0 (es) | 1982-12-01 |
| DK154419C (da) | 1989-04-10 |
| EP0049403B1 (en) | 1984-05-30 |
| EP0049403A3 (en) | 1982-06-02 |
| ZA816564B (en) | 1982-09-29 |
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