ES505656A0 - Un procedimiento para preparar nuevos derivados de antraci- clina - Google Patents

Un procedimiento para preparar nuevos derivados de antraci- clina

Info

Publication number
ES505656A0
ES505656A0 ES505656A ES505656A ES505656A0 ES 505656 A0 ES505656 A0 ES 505656A0 ES 505656 A ES505656 A ES 505656A ES 505656 A ES505656 A ES 505656A ES 505656 A0 ES505656 A0 ES 505656A0
Authority
ES
Spain
Prior art keywords
anthracicine
derivatives
procedure
preparing new
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES505656A
Other languages
English (en)
Spanish (es)
Other versions
ES8302733A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Publication of ES8302733A1 publication Critical patent/ES8302733A1/es
Publication of ES505656A0 publication Critical patent/ES505656A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/215—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring having unsaturation outside the six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/26—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydration of carbon-to-carbon triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES505656A 1980-09-22 1981-09-21 Un procedimiento para preparar nuevos derivados de antraci- clina Granted ES505656A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55130645A JPS5756494A (en) 1980-09-22 1980-09-22 New anthracyclin derivative

Publications (2)

Publication Number Publication Date
ES8302733A1 ES8302733A1 (es) 1982-12-01
ES505656A0 true ES505656A0 (es) 1982-12-01

Family

ID=15039201

Family Applications (2)

Application Number Title Priority Date Filing Date
ES505656A Granted ES505656A0 (es) 1980-09-22 1981-09-21 Un procedimiento para preparar nuevos derivados de antraci- clina
ES514919A Granted ES514919A0 (es) 1980-09-22 1982-08-11 "un procedimiento para preparar un derivado de antraciclina".

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES514919A Granted ES514919A0 (es) 1980-09-22 1982-08-11 "un procedimiento para preparar un derivado de antraciclina".

Country Status (10)

Country Link
US (1) US4355026A (en, 2012)
EP (2) EP0049403B1 (en, 2012)
JP (1) JPS5756494A (en, 2012)
AU (1) AU542707B2 (en, 2012)
CA (1) CA1177070A (en, 2012)
DE (1) DE3163896D1 (en, 2012)
DK (1) DK154419C (en, 2012)
ES (2) ES505656A0 (en, 2012)
PH (3) PH18087A (en, 2012)
ZA (1) ZA816564B (en, 2012)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4411834A (en) * 1978-02-09 1983-10-25 Farmitalia Carlo Erba, S.P.A. Preparation of II-deoxy anthracycline antibiotics
IT1210476B (it) * 1981-05-28 1989-09-14 Erba Farmitalia Antracicline.
CA1187434A (en) * 1981-08-11 1985-05-21 Akihiro Yoshimoto Anthracycline antibiotics and their preparation method
US4563444A (en) * 1982-05-26 1986-01-07 Farmitalia Carlo Erba S.P.A. Anthracycline glycosides, use and compositions containing same
FR2551057B1 (fr) * 1983-08-30 1986-07-18 Hoechst Lab Nouveaux aglycones utiles pour la preparation des antibiotiques et des antitumoraux de la serie des anthracyclines et leurs procedes de preparation
GB8426672D0 (en) * 1984-10-22 1984-11-28 Erba Farmitalia Pharmaceutical compositions
IT1190399B (it) * 1985-10-04 1988-02-16 Zambon Spa Processo per la preparazione di composti carbonilici otticamente attivi
JPH0372492A (ja) * 1990-08-04 1991-03-27 Mercian Corp アントラサイクリン誘導体及びその製造方法
WO1999058543A1 (en) * 1998-05-13 1999-11-18 Instytut Farmaceutyczny New n-alkyloxycarbonyl derivatives of monosaccharides l-acosamine and l-daunosamine
WO2000056267A2 (en) * 1999-03-19 2000-09-28 Waldemar Priebe Methods and compositions for the manufacture of c-3' and c-4' anthracycline antibiotics

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1527892A (fr) * 1967-03-15 1968-06-07 Rhone Poulenc Sa Nouveau procédé de préparation de l'antibiotique 13057 r.p.
YU33730B (en) * 1967-04-18 1978-02-28 Farmaceutici Italia Process for preparing a novel antibiotic substance and salts thereof
US4020270A (en) * 1974-05-02 1977-04-26 Societa' Farmaceutici Italia S.P.A. L-lyxohex-1-enopyranose derivative
GB1470860A (en) * 1974-10-29 1977-04-21 Farmaceutici Italia Anthracycline glycosides
GB1500421A (en) * 1975-01-22 1978-02-08 Farmaceutici Italia Optically active anthracyclinones
GB1527050A (en) * 1976-06-19 1978-10-04 Farmaceutici Italia Optically active anthracyclinones
NL7900869A (nl) * 1978-02-09 1979-08-13 Erba Farmitalia Anthracyclinenantibiotica.
GB2036021B (en) * 1978-11-21 1983-04-13 Erba Farmitalia Antitumour antibiotics
GB2067552B (en) * 1980-01-16 1984-02-29 Erba Farmitalia Anthracyline derivatives

Also Published As

Publication number Publication date
US4355026A (en) 1982-10-19
AU542707B2 (en) 1985-03-07
ES8306765A1 (es) 1983-06-01
DK154419B (da) 1988-11-14
CA1177070A (en) 1984-10-30
EP0086430A1 (en) 1983-08-24
EP0049403A2 (en) 1982-04-14
PH18633A (en) 1985-08-23
PH18087A (en) 1985-03-20
DK418581A (da) 1982-03-23
JPS5756494A (en) 1982-04-05
ES514919A0 (es) 1983-06-01
EP0049403B1 (en) 1984-05-30
JPS6121559B2 (en, 2012) 1986-05-27
DK154419C (da) 1989-04-10
EP0049403A3 (en) 1982-06-02
ZA816564B (en) 1982-09-29
EP0086430B1 (en) 1985-11-06
AU7553281A (en) 1982-04-01
ES8302733A1 (es) 1982-12-01
PH18162A (en) 1985-04-03
DE3163896D1 (en) 1984-07-05

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970303