PH12017501567A1 - Ophthalmic composition - Google Patents

Ophthalmic composition

Info

Publication number
PH12017501567A1
PH12017501567A1 PH12017501567A PH12017501567A PH12017501567A1 PH 12017501567 A1 PH12017501567 A1 PH 12017501567A1 PH 12017501567 A PH12017501567 A PH 12017501567A PH 12017501567 A PH12017501567 A PH 12017501567A PH 12017501567 A1 PH12017501567 A1 PH 12017501567A1
Authority
PH
Philippines
Prior art keywords
pcnt
ophthalmic composition
salt
hyaluronic acid
ophthalmic
Prior art date
Application number
PH12017501567A
Inventor
Takanori Ohno
Masahiro Kawahata
Original Assignee
Santen Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd
Publication of PH12017501567A1 publication Critical patent/PH12017501567A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The present invention addresses the problem of maintaining a high retention rate of the kinematic viscosity of an ophthalmic composition, such as an ophthalmic solution containing hyaluronic acid or a salt thereof. Provided is an ophthalmic composition containing 0.001-0.5 pcnt (w/v) of hyaluronic acid or a salt thereof, 0.0005-0.02 pcnt (w/v) of chlorhexidines, 0.03-1.5 pcnt (w/v) of propylene glycol, and 0.015 pcnt (w/v) or less of ethylenediaminetetraacetates.
PH12017501567A 2015-03-06 2017-08-31 Ophthalmic composition PH12017501567A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2015045065 2015-03-06
PCT/JP2016/056861 WO2016143708A1 (en) 2015-03-06 2016-03-04 Ophthalmic composition

Publications (1)

Publication Number Publication Date
PH12017501567A1 true PH12017501567A1 (en) 2018-02-05

Family

ID=56880167

Family Applications (1)

Application Number Title Priority Date Filing Date
PH12017501567A PH12017501567A1 (en) 2015-03-06 2017-08-31 Ophthalmic composition

Country Status (7)

Country Link
JP (2) JP6716293B2 (en)
KR (1) KR102607126B1 (en)
MY (1) MY190393A (en)
PH (1) PH12017501567A1 (en)
SG (2) SG11201707117SA (en)
TW (2) TW202114648A (en)
WO (1) WO2016143708A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20190068575A (en) * 2016-10-14 2019-06-18 이콤 메디칼 게엠베하 Establishment of ocular surface homeostasis, recovery and preservation method
JP6603785B2 (en) * 2017-12-08 2019-11-06 千寿製薬株式会社 Aqueous solution containing water-soluble polymer
CN114845734A (en) * 2019-12-27 2022-08-02 乐敦制药株式会社 Aqueous composition
CN112870216A (en) * 2021-01-29 2021-06-01 张宽才 Pharmaceutical composition, preparation and application
JP2023022569A (en) * 2021-08-03 2023-02-15 小林製薬株式会社 Eyewash composition
CN114391550B (en) * 2022-01-06 2022-11-22 江南大学 Water-soluble chlorhexidine antibacterial agent and preparation method and application thereof
WO2024135344A1 (en) * 2022-12-21 2024-06-27 ライオン株式会社 Ophthalmic product

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1072376A (en) * 1996-09-02 1998-03-17 Ofutekusu:Kk Eye drop aqueous solution comprising hyaluronic acid
JPH1160505A (en) * 1997-05-20 1999-03-02 Senju Pharmaceut Co Ltd Antiseptic composition
JPH115744A (en) * 1997-06-16 1999-01-12 Toa Yakuhin Kk Aqueous solution preparation for external use containing hyaluronic acid
JP2002193815A (en) * 2000-12-25 2002-07-10 Ophtecs Corp Eye drops for prevention of corneal drying for ophthalmic operation
JP2003002837A (en) * 2001-06-21 2003-01-08 Lion Corp Composition for aqueous skin care preparation and method for preventing clouding of liquid composition
JP4431817B2 (en) 2002-03-08 2010-03-17 第一三共株式会社 Eye drops containing tetrazole derivatives
JP4694773B2 (en) * 2003-06-06 2011-06-08 ロート製薬株式会社 Mucosal liquid composition
CA2577022A1 (en) * 2004-08-13 2006-02-23 Angiotech International Ag Compositions and methods using hyaluronic acid and hyluronidase inhibitors
WO2008050776A1 (en) 2006-10-26 2008-05-02 Senju Pharmaceutical Co., Ltd. Ophthalmic aqeous liquid preparation
JP5595206B2 (en) * 2009-09-30 2014-09-24 ロート製薬株式会社 Ophthalmic liquid composition
KR101906631B1 (en) * 2011-06-23 2018-10-10 산텐 세이야꾸 가부시키가이샤 Ophthalmic solution containing hyaluronic acid or salt thereof and propylene glycol

Also Published As

Publication number Publication date
SG11201707117SA (en) 2017-10-30
JP2020138979A (en) 2020-09-03
TW202114648A (en) 2021-04-16
JP2016166195A (en) 2016-09-15
MY190393A (en) 2022-04-20
KR20170122773A (en) 2017-11-06
TWI745287B (en) 2021-11-11
SG10201901426WA (en) 2019-03-28
TW201705948A (en) 2017-02-16
KR102607126B1 (en) 2023-11-27
JP6716293B2 (en) 2020-07-01
WO2016143708A1 (en) 2016-09-15

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